Very exciting news that Florian Wilfling is the recipient of this year‘s Walther Flemming Award!

We are very happy that our newest postdoc colleague, Els, has recently started in the lab! She will be joining our team investigating degradation of nuclear pore complexes by autophagy, using expertise gained during her postdoc time with Christian Schlieker. Welcome Els 🎉🎉🎉

We had a great lab dinner this week and enjoyed some traditional Frankfurt cuisine. It was fantastic to have (almost) everyone together including rotation students and visitors!

We spent three days in Staufen discussing science, exchanging insightful ideas, and having lots of fun! A big thank you to the The Wilfling Lab and Florian Wilfling! We are looking forward to next year's retreat!

✳️ New Review discussing the mechanisms of degradation of nuclear components across eukaryotes: #Autophagy as a caretaker of #nuclear integrity

🖊️ E.Boyle Emily Boyle & F. Wilfling Florian Wilfling The Wilfling Lab Max Planck Institute of Biophysics

➡️ bit.ly/3KUz55Q

#Atg39 #NuclearPoreComplex

✳️´Puzzling out nuclear pore complex assembly´ in the new Review by 🖊️A. Penzo Arianna Penzo & B. Palancade Palancade lab.
Understanding NPCs to learn about the biogenesis of multiprotein complexes

➡️ bit.ly/3QTAehY

#NuclearEnvelope #NuclearPore

Very excited to share that our review on #nucleophagy is now out in FEBS Letters 🎉
doi.org/10.1002/1873-3…

Emily Boyle and Florian Wilfling discuss the diverse mechanisms for degradation of nuclear components by #autophagy across eukaryotes.

It‘s out on biorxiv!

Thanks to Oda H Schiøtz, Sven Klumpe, Dustin Reed Morado Matthias Pöge, Jonathan Schneider Florian Beck and Christopher Thompson for the productive work! Amazing colleagues, and Juergen M. Plitzko steadily supporting and enabling it all!

biorxiv.org/content/10.110…

Glad to finally share our manuscript on “Serial Lift-Out” by the amazing twitterless Oda Schiøtz, Jürgen Plitzko, Christoph Kaiser , and myself. Doing multiple sections from single lift outs showing beautiful C. elegans ultrastructure 🤯 I could watch it all day 🤩How did we get there?

An Ostern endet die christliche #Fastenzeit . Was sagt die Wissenschaft zum Fasten? Was hat das mit #Autophagie zu tun? Unsere Doktorandin Pia Erdbrügger beschäftigt sich mit diesem Prozess der zellulären Abfallentsorgung und erklärt, was dahinter steckt. 👉biophys.mpg.de/2746239/autoph…

The Wilfling group recently welcomed our second post-doc colleague, Shan Jiang. Having studied protein phase separation in yeast during her previous postdoctoral studies, she will now be investigating the degradation of phase-separated condensates via autophagy. Welcome Shan!

This was a fun challenge! empiar 11275, A full chlamydomonas cell. Looks so cool in 3D! I used a pre-trained UNet from @OrsDragonfly3D and trained it to classify 13 different classes. Quite a different challenge than my usual cryoET, but very worth it! SwuliusLab

Scientists Cristina Capitanio Anna Bieber from the Baumeister and Schulman labs at #MPIB , together with
Florian Wilfling from Max Planck Institute of Biophysics, released an amazing paper PNASNews about the membrane ultrastructure of #phagophores !
➡️ pnas.org/doi/10.1073/pn……

🥳 Congratulations to you all!

'We are all humans & all deserve the same #respect , love & attention.' The topic of disability is close to the hearts of our newly elected representatives for severely disabled persons Pia Erdbrügger (middle), Shau Chung Shin (left) & Mun Siong (right) #equalopportunities

We are proud to welcome our new post-doc colleague, Javier Lizarrondo (Javier). He will use the tremendous structural biology skills from his Ph.D. at SPC Facility & Garcia-Alai Lab @EMBL Hamburg @EMBL to study membrane remodelling proteins involved in the generation of the phagophore. Welcome, Javier! 😄

Congratulations to The Wilfling Lab PhD student Pia Erdbrügger for receiving an Evangelische Studienwerk PhD fellowship funded by BMBF and also for being elected as First Representative for Severely Disabled Persons at Max Planck Institute of Biophysics! Both fantastic achievements 🎉

Our work on yeast autophagy biogenesis is out in PNAS:

pnas.org/doi/10.1073/pn…

In this study we present the membrane ultrastructure of #phagophores , their biophysical properties and the contact sites involved in their biogenesis, spearheaded by Cristina Capitanio and @Anna_bieber_ab.

In 2 weeks from now we'll start a new season of mito911 series! Join us with Florian Wilfling The Wilfling Lab to know more about #autophagy ! Aligning Science Across Parkinson’s michaeljfox.org

#JobOffer : Looking for a #Postdoc position in the field of #MolecularBiology ? Passionate about #autophagy , #cryoEM and #MassSpec ? #Apply now to support the @Wilfling_Lab in investigating cargo recruitment during #autophagosome biogenesis. More info 👉biophys.mpg.de/2009720/open-p…

Warmest congratulations to our research group leader Florian Wilfling (@WilflingLab) on receiving a prestigious ERC Starting Grant for his research on #autophagosomes which help the cell remove its waste! What a great success🥳👏European Research Council (ERC) #ERCStG
👉biophys.mpg.de/2677330/erc-gr…