Our new paper that uses machine learning to generate a suite of novel protein cages has just been published: cell.com/structure/full…

Our creation of 'ligand-operable cages' -- designed protein cages that disassemble when they bind a specific cellular protein -- has been published: pubs.acs.org/doi/10.1021/ac…

Our latest work on solving the cryo-EM problem for small therapeutic proteins is finally out.
pnas.org/doi/10.1073/pn…
Congrats to Roger and the lab!

‘Rigidified Scaffolds for 3-Angstrom Resolution Cryo-EM of Small Therapeutic Protein Targets’
Congrats Roger Castells Kyle Meador and team!
With our imaging scaffolds, we report a 2.9A structure for a ~19 kDa KRAS protein oncogenic mutant.
biorxiv.org/content/10.110…

Designing Protease-Triggered Protein Cages

#proteincages #proteases #proteindesign

pubs.acs.org/doi/abs/10.102…