This is Hari. He never has to ask what time a party is. Because they all start when he walks in. 13/10 (IG: hari_1121)

I’m sure that’s not their intent…

Out in nature concurrent with #AACR24
Two papers on biochemistry and preclinical characterization of Revolution Medicines’ RAS(ON) multiRAS inhibitor, with a focus on #PancreaticCancer
KenOliveLab Ben Stanger Der Lab at UNC
nature.com/articles/s4158…
nature.com/articles/s4158…

Autogene cevumeran, a therapeutic mRNA vaccine for pancreatic cancer, continued to show benefit in a three-year follow-up, according to Vinod Balachandran, MD. #AACR24 Vinod BalachandranMD Memorial Sloan Kettering Cancer Center bit.ly/3TRUZdV

Investigation by the amazing Vinod BalachandranMD! These results blow me away and tell me that there is hope at last for pancreatic cancer! Phase 2 trial will be key. Good luck!

This is really big news!

Follow-up Ph1 data for mRNA-based individualized cancer vaccine candidate autogene cevumeran (BNT122) show: 6 of 8 patients with an immune response to the investigational treatment remained tumor-free up to 3 years post treatment. #AACR24 #cancerresearch #oncology

Well good morning

Cardiac researcher takes her work from ‘bench to bedside to Wall Street’: check out this feature on our own Farah Sheikh

today.ucsd.edu/story/medical-…

We're hiring!

Research Associate - Hoffmann Lab: bit.ly/3J91oMR

Senior Research Technologist - Flow Cytometry Core: bit.ly/3wKUeeG

Senior Research Technologist - Histology and Light Microscopy Core: bit.ly/49I2ydS

and more: bit.ly/3TVekMD

nejm.org/doi/full/10.10…

Another null trial in patients post-MI!

We have 3 heart failure trials (EMPEROR-Preserved, EMPEROR-Reduced, EMPULSE), 1 CKD trial (EMPA-Kidney), & 1 post-MI trial (EMPACT-MI) which show no mortality benefit with empagliflozin.

OK so the moon is going to block out the sun and the most cicadas we've seen in over 200 years and earthquakes. OK we get it already nytimes.com/2024/04/04/sci…

3 body problem is a great show, but the pancreas cancer patient character hits a little close.

A Cellular Dictionary of Developing Human Heart👹
#SpatialTranscritomics #Visium
+150-gene #InSituSequencing
~70k spots, 16 hearts 6-12th p.c.w

There are Nerve #FibroAdipogenicProgenitor & #Pericyte 😊

'count matrix was filtered for MALAT1, ribosomal, mitochondrial, and…

Gladstone's Emily Bulger and Benoit Bruneau are interviewed about their study that appears on the March cover of the journal Development (@Co_Biologists)
bit.ly/3PR4N6y

I’m looking California but feeling Minnesota (oh yeah). Great visit at the Lillehei Heart Institute

TBXT dosage keeps gastrulation on time

Read this Research Highlight showcasing work from Emily Bulger Emily Bulger, Ivana Muncie-Vasic, Ashley Libby, Todd McDevitt Todd McDevitt and Benoit Bruneau Benoit Bruneau Gladstone Institutes UC San Francisco:
journals.biologists.com/dev/article/15…

To find out more about the people behind the paper, we caught up with first author Emily Bulger Emily Bulger and corresponding author Benoit Bruneau Benoit Bruneau.

Read the interview: journals.biologists.com/dev/article/15…