Mini - 🧵...

I came across a few difficult-to-find drawings of concepts related to bleeding vessels and technical pointers on vessel ligation.

First: a drawing showing that *partial* transection of a vessel often leads to much more bleeding than complete transection.

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1/ The long-awaited OS results from #KEYNOTE -564 are out NEJM! The 1st phase 3 trial to demonstrate a survival benefit for adjuvant treatment in #RCC .

nejm.org/doi/full/10.10…

‼️ATTENTION‼️

Save this video in your smartphone! 📱

For the next time you have to explain to your patient the valve mechanism of the median lobe and the bladder damage.🥑

And why they can’t use alfa-bloq and 5-ARI in this situation…🙄

#BPH #MedianLobe
#MiLEP #HoLEP #EEP

We are looking for Canadian med students to participate in a study about the impact of gender on residency program selection. We are trying to understand barriers for pursuing surgical training. It’ll take 5 mins max. Please check out the link. Thanks

redcap.lawsonresearch.ca/surveys/?s=TMA…

There were 12 #measles cases in Canada last year, all travel-related. There are 20 cases in the first two months of this year, several community-acquired. And #vaccination rates are falling globally. It’s the *context* that matters. google.com/gasearch?q=pic…

Testosterone therapy does not increase risk of prostate events (cancer or BPH)
Mayo Clinic Urology #MayoUroHawaii24

ncbi.nlm.nih.gov/pmc/articles/P…

Plant-based diet in prostate cancer:
- lower risk of elevated PSA
- lower risk of aggressive cancer
- less progression on AS
- less progression with BCR

Eye-opening even for a confessed carnivore like me
Stacy Loeb, MD #MayoUroHawaii24

Late to respond to this, but have a few comments. First, kudos to Jim Hu Tenny Zhang Elie Kaplan-Marans, MD for this study. Particularly valuable following TRAVERSE, as it helps focus on a new “battle zone” for TTh and PCa.
1/n

What takes 5 minutes after RALP and prevents pelvic lymphoceles?

Are you doing this yet?

Lahey Urology

auanews.net/issues/article…

One of the original papers by Jackson and Pratt describing their drain (which they of course called the 'Jackson-Pratt'). It was from 1972.

At the end, they even told people where to order it. 😬

Jackson and Pratt were neurosurgeons at the Naval Hospital in Pendleton, CA. 🧠

Continuous Bladder Irrigation

Enfortumab Vedotin + pembro shows broad spectrum of activity for RR PFS and OS in all subgroups. This includes subsets such as lymph node disease, liver mets, PD-L1 status, upper tract disease, platinum eligibility. This +ve data underlines EVP as a new standard of care #GU24

I'm thrilled to announce, together w/ UroToday.com Prostate Cancer Foundation, our first #prostatecancer Journal Club for Patients. First up is ProtecT, with Profs. Hamdy and Donovan and our Patient Advocates.

Here's the presentation: urotoday.com/video-lectures…
And the Q&A:
urotoday.com/video-lectures…

In a randomized trial to assess the impact of stent diameter on stent symptoms and quality of life, <7 Fr stents were associated with less urinary incontinence, faster return to work and fewer sexual side effects Sofi Butori Luis Rico Pablo Contreras
liebertpub.com/doi/abs/10.108…

Operations take whatever length of time they take, and none of people asking how much longer you’ll be are going to be there afterward to manage postoperative complications or explain to the patient what went wrong.

Full text available now:
ProBE-PC RCT, TR vs TP prostate biopsy=
No significant difference in 'confirmed or suspected' infections (763 patients)

Using a more 'strict' definition of infection:
TR 1.7% vs TP 1.4%

jurology.com/eprint/ID23ERJ… Urological Institute@AlbanyMed #ProstateCancer #UroSoMe

Learn more about the #1 cancer in Canadian men at prostatecanada.ca

VESPER Trial: survival endpoints at 5 years in an open-label, randomized, phase 3 study

Overall, ITT, in perioperative setting : no association of OS with dd-MVAC vs GC treatment (64% vs 56%, HR 0·79)

In the NAC subgroup: OS at 5 years improved in the dd-MVAC group (66% vs

Pre-op PSA low (~ 2ng/ml), RP path is node-negative Gleason 9 (other details don't matter for this)

Post-op PSA undetectable

Will continue PSA q 4 months

Presume people get imaging for low-PSA production, high risk cancers but which and how often?

Any papers/data?

Impt question below to start off the new year. How should TRAVERSE influence your clinical practice re T therapy (TTh)? My thoughts. A 🧵: