Join us as we #StepUpForLiverHealth this World Liver Day 🌍 Let's unite #communities , medical experts, and #policymakers across Europe and beyond to combat #liverdiseases and promote #awareness . With the #EUelections approaching, it's the perfect time to #Vote4Patients and…

#Neutrophils have diverse effector functions that are altered in #IBD and monogenic diseases with IBD-like phenotype

More in this REVIEW nature.com/articles/s4157…

This Figure shows the interactions of known microbially modified bile acids with common host ligand receptors and the phenotypic response

Find out more in this Perspective on the changing metabolic landscape of bile acids nature.com/articles/s4157…

#microbiome

new highlight online on recent research by Susan Bullman CJohnstonLab, #sharedit link rdcu.be/dEUMI

Also, how awesome is this artwork by mark belan | science illustrator + info designer 👌🏻

New content online: Artificial intelligence in liver cancer — new tools for research and patient management dlvr.it/T5b5cN

It’s about time to launch programes on LIVER FIBROSIS screening among high-risk population, similarly to colorectal and lung cancer.

This must-read review in Nature Reviews Gastroenterology & Hepatology describes the ideal program.

#livertwitter rdcu.be/dExwx #medX

Many countries have incorporated population screening programmes for cancer (such as colorectal and lung cancer) into their health-care systems.

What can we learn from these programmes for #liverfibrosis screening initiatives?

Read more rdcu.be/dExwx

Fermented foods have gained popularity owing to their health-promoting potential - this REVIEW discusses the benefits of #fermentedfoods in gut health and disease, and how specific microbes, food components and bioactive compounds exert their effects
rdcu.be/dExvj

From our April issue, this REVIEW discusses the pathophysiology of gastro-oesophageal reflux disease and the implications for diagnosis and management, different GERD phenotypes have different degrees of reflux & severity of symptoms
rdcu.be/dExtN

#GORD #GERD #reflux

Out in nature concurrent with #AACR24
Two papers on biochemistry and preclinical characterization of Revolution Medicines’ RAS(ON) multiRAS inhibitor, with a focus on #PancreaticCancer
KenOliveLab Ben Stanger Der Lab at UNC
nature.com/articles/s4158…
nature.com/articles/s4158…

A Review in Nature Reviews Gastroenterology & Hepatology provides an overview of barrier function across the gut–brain axis and examines the role of the gut microbiota in communication across and between these specialized gastrointestinal and brain barriers in health and disease. 🔒 go.nature.com/3J8Js4Z

New content online: Promoting allyship to support and uplift the LGBTQIA+ community dlvr.it/T577n6

There is currently not a single bile acid detection protocol that can fully capture the true diversity of bile acids, and, as a result, the ability to comprehensively detect and describe the extensive bile acid metabolic network represents a 21st century analytical challenge!!!

Great opportunity, details in the link below 👇

This is a must read.
I reviewed it (acknowledged) and thought this was a very important paper. We indeed need to rethink #biochemistry and #physiology behind #bileacids , given emerging data on their diversity (and most likely also other metabolites).
#lipidomics #metabolomics

NEW! PERSPECTIVE

The changing metabolic landscape of bile acids – keys to metabolism and immune regulation
By Pieter Dorrestein Knight Lab & colleagues
nature.com/articles/s4157…

Readcube link rdcu.be/dDNw0

Excited that the perspective on bile acid modifications with Knight Lab is out. It is aimed to be a bit provocative. IMO - we need to rewrite and update all biochemistry textbooks. These are some of the most important molecules in biology. See rdcu.be/dDHoC

🚨📢We're pleased to be launching a new series of articles—Climate Chronicles—that document the characteristics and changes of select climate variables and topics for each year📢🚨

Check out the Collection below to read up on what happened in 2023.

nature.com/collections/gh…

Thrilled to be sharing the wonderful news that work from our lab Yisu Gu Dr Emily Thornton and Teichlab Raquel Bartolomé-Casado has been published today in nature ! Go have a read to learn more about how tissue microniches shape Treg function in the intestines🎉nature.com/articles/s4158…

New treatment will transform people's lymph nodes into ‘mini livers’

The first person has received the therapy, made by @LyGenesis, as part of a trial for people with liver failure and can’t get a transplant.

For nature, w/ Valérie Gouon-Evans Michael Hufford
nature.com/articles/d4158…