Excited to share two preprints in my lab on computational lineage tracing (LT) of single cells.
Preprint #1 - Benchmarking of mtDNA lineage tracing: biorxiv.org/content/10.110…
Preprint #2 - A phylodynamics model framework (scPhylox) with single-cell LT data: biorxiv.org/content/10.110…

I presented my work on selective sweeps in range expansions on the conference “Mutations in time and space” in Edinburgh #MITS

Great talks and interactions!

Sad it’s already ending today 🥲

Parasites: the silent puppeteers of the food web? Eizaguirre Lab and Dr WeiniHuang shed light on how these tiny organisms influence predator-prey dynamics in their new study. royalsocietypublishing.org/doi/10.1098/rs…

Marc Williams on rates of aneuploidy in normal tissues #MITS24

Nathaniel Mon Pere on clonal competition in aging haematopoiesis #MITS24

Today Nathaniel will also talk about this work during the very first session of the mutationmeeting

and Francesco Terenzi will have a poster later today in the afternoon presenting more details on the SFS modelling.

I am very excited about our newest preprint on the emerging dynamic fitness landscape of haematopoietic stem cells trough clonal competition.

biorxiv.org/content/10.110…

This work has been pushed by the fantastic Nathaniel and Francesco Terenzi.

great to have Sara (Jabbari) School of Mathematics coming to qmul talking about using mathematical modelling to aid in the development of anti-resistance treatments, applying drugs in a more reasonable order under immune response and finding a better target in efflux pump network.

Thanks Arda Durmaz and Valeria Visconte for a nice summary highlighting our theory integrating bulk and single cell data. elifesciences.org/articles/95513 eLife - the journal work done together with Benjamin Werner , Nathaniel Mon Pere and Marius Moeller

I am delighted to share my recent work, the product of an excellent collaboration with Kaiyuan Zhu and Jens Luebeck in the Bafna lab, that describes CoRAL: our tool for reconstructing focal amplifications, like ecDNA, from long-read data: biorxiv.org/content/10.110…

Feeling honored. Thanks for the new year message and happy the year of dragon. Ginestra Bianconi Queen Mary Maths

Great to see Esther Baena talking about the beautiful stories of finding the castration resistance progenitor cells by a marker LY6D and how to target LY6D+ cells before progression to avoid resistance. Looking forward to work our story about prostate progenitor compartments.

We are having @robjohnnoble.bsky.social Rob today talking about his recent work on cancer evolution in space and universal tree balance indices. Join us on Queen Mary Maths MB503 qmul at 13:00 uk time or on zoom qmul-ac-uk.zoom.us/j/81250086190