Read a Special Commentary from the April issue—
#Somatic Mutations in Normal Tissues: Calm Before the Storm, by Zahraa Rahal, Paul Scheet 🌮🧬, and Humam Kadara.
bit.ly/4dkcPiG
MD Anderson Cancer Center

There's big potential to change the way and the timing that pancreatic cancer is detected. Anirban Maitra and I teamed up for this new The Lancet essay
thelancet.com/journals/lance… #AI

Building a multimodal spatial-omics atlas could point to targets for early detection or interception of #LungCancer . 

Our fellow Dr. Ansam Sinjab shares findings at #AACR24 : bit.ly/3VMoJeP Ansam Sinjab 🇺🇸🇸🇾🇱🇧 Linghua Wang, MD, PhD Humam Kadara AACR #EndCancer

Thank you #AACR24 for the opportunity to present our work in a minisymposium this year! Supported by our dream collaborative team at MD Anderson Cancer Center, we are advancing the frontiers of how we look at lung #precancer , and bringing hope to the hype of early intervention 🫁

Excited for the #AACR24 profiling tumor ecosystems in native tissue context plenary session. Forget the solar eclipse and check out minisymposium talk abstract 3893 by our group Ansam Sinjab 🇺🇸🇸🇾🇱🇧 on profiling #lungcancer and #precancer using multimodal #spatial omics AACR #endcancer

Happening now at #AACR24 : Dr. Scott Kopetz, AACR Waun Ki Hong Award recipient, is giving a lecture on Adaptive Resistance in BRAF- and KRAS-mutated #ColorectalCancer . Scott Kopetz #EndCancer

✨Highlighting a Cancer Discovery Special Issue Commentary for #AACR24 : Somatic Mutations in Normal Tissues: Calm Before the Storm - by Zahraa Rahal Paul Scheet 🌮🧬 & Humam Kadara doi.org/10.1158/2159-8… MD Anderson Cancer Center

Great first talk at #AACR24 opening plenary session on single cell & spatial omics and their power to understand cancer. ICYMI check our recent @nature paper how an atlas we generated of lung epithelial cells led us to identify #lungcancer progenitors
nature.com/articles/s4158…

'Let us aim to create a future in which the seeds of cancer can be rendered infertile long before they take root. The path ahead is both daunting and hopeful, yet it is only through collective endeavor and innovation that we can aspire to maintain calm and avoid the storm.'

What are the hallmarks of Precancer?
See our commentary in Cancer Discovery from the NCI Division of Cancer Biology TBEL Consortium (tbelprogram.org/index.html) driven by an exceptional cache of trainees & early career investigators.
aacrjournals.org/cancerdiscover…
Ken Lau Lab Lyssiotis Lab Jimin Min

Somatic Mutations in Normal Tissues: Calm before the Storm
By Humam Kadara Paul Scheet 🌮🧬 Zahraa Rahal MD Anderson Cancer Center
aacrjournals.org/cancerdiscover…

Enjoyed putting this piece led by ⁦⁦Zahraa Rahal⁩ . We need to make sense of mechanisms that shape the fate of mutant cells in “normal” tissues, e.g., tissue injury, inflammation, etc. 🙏Elizabeth McKenna Cancer Discovery for letting us share our thoughts! aacrjournals.org/cancerdiscover…

Read Cancer Discovery's #ResearchWatch :
Alveolar Intermediary Cells Act As Progenitors for KRAS-Mutant #LungCancer , a summary of the study by Guangchun Han, Ansam Sinjab 🇺🇸🇸🇾🇱🇧, Zahraa Rahal, Anne Lynch, Jichao Chen, Linghua Wang, MD, PhD, Humam Kadara et al.
bit.ly/3TLuGas
@mdandersonnews

Thank you Cancer Discovery for highlighting our recent paper about alveolar intermediary cells acting as precursors for #lungcancer #endcancer

aacrjournals.org/cdnews/news/13…

📢Are you passionate about studying why and how cancer patients relapse after treatment? Are you enthusiastic about the tumor microenvironment? We are still growing and recruiting motivated people to work in an exciting environment
Fox Chase Cancer Center
Lewis Katz School of Medicine
Please RT

Nature research paper: An atlas of epithelial cell states and plasticity in lung adenocarcinoma go.nature.com/3wx7qE3

Leveraging multimodal and dynamic spatial imaging and molecular profiling in 2D and 3D, our team is pursuing a deeper exploration of the critical transition process during lung tumorigenesis, from normal epithelial cells to precancerous lesions and ultimately to invasive cancer.

Our researchers have built a new atlas of lung cells, uncovering new cellular pathways and precursors in the development of lung adenocarcinoma.

Learn about this work from our Drs. Humam Kadara and Linghua Wang: bit.ly/3SXUHS3 Humam Kadara Linghua Wang, MD, PhD #LungCancer …

Excited to finally share our @nature publication! A thrilling discovery, yes, but for me, a trainee privileged to contribute, it’s a tale of perseverance, teamwork, and personal growth at every conceivable level. Kudos to the @Humam_kadara lab family and collaborators ✨!

Congratulations Humam Kadara Linghua Wang, MD, PhD Ansam Sinjab 🇺🇸🇸🇾🇱🇧 and the MD Anderson Cancer Center #LungCancer team. Out in nature this morning:
An atlas of epithelial cell states and plasticity in lung adenocarcinoma
nature.com/articles/s4158…