Take homes from Courage and Innovation Symposium session 2.

Nitasha Sarswat: amyloid fibril depleters & CRISPR are on the horizon.

Jeanne DeCara: use steroids early in checkpoint inhibitor myocarditis, rechallenging ICU risky.

Hena Patel MD: most ACEi & spiro ok w lactation in peripartum CM.

Great program put together by Ben Chung MD & Sara Kalantari MD!

Ben took a picture of the 1 HFrEF slide 😂. Appreciated the opportunity to talk about the growing evidence for #SQUAD -therapy for HFpEF

x.com/MarkBelkinMD/s…

Double-dipping on PH learning from the homecoming of Dr Mardi Gomberg as Cardiology Grand Rounds lecturer yesterday and the keynote speaker Courage and Innovation Symposium today!

Asked how he and Yale University would respond to a person at the university who called for the genocide of Jews, Yale President Peter Salovey said:

“What was asked of other university leaders at recent Congressional hearings has raised questions about our policies and practices. Let me…

Excellent discussion on PAH & comorbidities and disease modification CVCT - CardioVascular Clinical Trialists. Thanks to the organizers Faiez ZANNAD Jason Weatherald MD Olivier Sitbon Jean-Luc Vachiery 🫀 Vallerie McLaughlin Dr Mardi Gomberg Yogesh Reddy Mitchell Psotka Steven Kawut The Pulmonary Hypertension Association ATS PC Assembly

Its official. I am an endowed professor of clinical research at GW SMHS ❤️❤️GW Thx to all my collaborators, research teams,clinical staff,and mentors!

Its official I am now Walter G Ross endowed professor of clinical research at GW Thanks to all my mentors, collaborators and research teams! ❤️GW

Starting in 20 minutes! Don’t miss out! CardioNerds

CardioNerds Journal Club Additional comment on AEs- some had symptoms of an 'increase in prostacyclin' they didn't need as much- this is a hot topic Anjali Vaidya MD 🫀 Ryan J Tedford MD thoughts?

Finished at MACCS. Great job done by my colleagues!

A great meeting

Dr Mardi Gomberg-Maitland presents phenotypic and enrichment of PAH trials. She emphasizes that “These are not new issues” and highlights what’s new in 2021. #CVCT2021 CVCT - CardioVascular Clinical Trialists Dr Rani Khatib FESC Diego Araiza MD Dr.Rajiv Sankaranarayanan Aaysha Cader Alex Nowbar Alexander Hajduczok, MD 🇺🇦🙏 Anju Bhardwaj MD FACC

Might Bayesian analysis help? Prof Eric Vicaut compares and contrasts Bayesian and Frequentist approaches in improving PAH trial design. #CVCT2021 CVCT - CardioVascular Clinical Trialists Aaysha Cader Carlos G Santos-Gallego, MD Diego Araiza MD Dr Rani Khatib FESC Harriette Van Spall, MD MPH Faiez ZANNAD

Excellent presentation by Dr Steven Kawut on practical issues to consider with PAH trial designs:
1. Background therapy
2. Placebo vs active control
3. Add-on vs Replacement
4. Single drug va strategies comparison. #CVCT2021 Diego Araiza MD Dr Rani Khatib FESC CVCT - CardioVascular Clinical Trialists

Dr Gomberg-Maitland describes a few enrichment strategies: using risk scores, adaptive enrichment with continued enrollment and randomization discontinuation trials, all aimed at identifying reliable responder and high-risk bio markers to best stratify. #CVCT2021 Dr Rani Khatib FESC

Hoping for a win

Brent NOWICKI (FINA): Siphiwe Baleka DEVE participar nas Olimpiadas 2021 - Sign the Petition! chng.it/PGHfCLFm via Change.org please help an old friend

Mike’s new job😀

Excited to be part of this team and looking forward to Phase 3 and beyond. nejm.org/doi/full/10.10…

vote for swimming!