The world probably does not need another AlphaFold related review from us but with Miguel Correa @[email protected] Jürgen Jänes and Delora Baptista we try to discuss here what is the impact of these methods specifically for research on human genetics and health annualreviews.org/content/journa…

LAST CALL FOR TICKETS! Just 6 more days until the 21st Harvard Microbial Sciences annual symposium!

Get your tickets at bit.ly/MSI_tix_2024

We've got amazing speakers, stunning SciArtists, and brilliant, fun-loving microbiologists like you!

This year, for the first…

Woohoo, our paper on the discovery of 65 new phages dependent on conjugative plasmids is published in it's final form today in Nature Communications ! Here follows a thread (1/ ) link.springer.com/article/10.103…

How to pick a problem. Today in Cell. 1/53
cell.com/cell/fulltext/…

Happy and super excited to share our discovery of a protein fractal! We unravel the surprisingly simple emergence of these marvellous structures and show it might have even been an accident of evolution. Read the full story here

nature.com/articles/s4158…

Or just stick around 🧵

Truly excited to see our latest article, in which we were surprised how phages that target conjugative plasmids are both so common and diverse, published!

A real tour de force from Natalia Quinones-Olvera and Siân Owen

nature.com/articles/s4146…

Well Dr. Hwang has done it again. Check out this wonderful paper on how large language models can better help us understand microbial genomes!

nature.com/articles/s4146…

Excited to share the final version of our genomic language model (gLM) paper out in Nature Communications! gLM learns hidden evolutionary patterns from metagenomes to expand functional inference beyond sequence and structure to include genomic context. nature.com/articles/s4146…

The phiKZ jumbo phages build a protein based nucleus to protect their DNA(!), but what do they do before the nucleus is built? Led by outstanding post-doc Deepto Mozumdar, here we identify host and phage proteins in an immediate early phage lipid vesicle.
biorxiv.org/content/10.110…

Four Einstein graduate students were honored for contributions to scientific research March 18 at the 28th annual Julius Marmur Award symposium. The awards are given by the Graduate Programs in the Biomedical Sciences to a select group. Learn more at bit.ly/3Tv2Y0e.

🚀Delighted to announce our recent publication in Science Magazine! We've unveiled novel Ruminococcal species🦠in the human gut, proficient in cellulose degradation🌾and finely tuned to our evolutionary journey.🔬Dive into the key findings with us. (1/9)
bit.ly/3wUX80G

Albert Einstein College of Medicine Announces Free Tuition in Perpetuity for All Medical School Students. Learn more at bit.ly/49xYywn. #MedicalSchool #MedEd #giving

Incredible news for Albert Einstein College of Medicine - Official ! Thank you Dr. Gottesman! nytimes.com/2024/02/26/nyr…

Preprint: Phages reconstitute NAD+ to counter bacterial immunity

tinyurl.com/NADPD

Many bacterial immune systems degrade NAD+ to deplete the cell of energy, halting phage replication

Ilya Osterman now discovered that phages can rebuild NAD and overcome defense

Open TT faculty position at the department of medicine at the University of Chicago! Come join us in Genetic Medicine, Biomedical data science, Oncology, or any of the other sections. Apply here: academicjobs.uchicago.edu/positions/1318…

My first paper from John Innes Centre with Tung Le is now out! 😃If you like bacteria and mobile genetic elements, consider reading our review on wonderfully weird #genetransferagents below👇sciencedirect.com/science/articl…

We are super excited that our review on the sulfated metabolome is online in Nature Chemical Biology today! Led by Gabriel and Snehal in the lab. Check it out!

nature.com/articles/s4158…

As a lab passionate about microbes 🦠 and metabolomes 🧪, we're thrilled by this article from Sam Light, A. Murat Eren (Meren) & AlexanderLittle 🥳. For insights into anaerobic respiration linking microbial energy to the gut metabolome, check it out!📚
doi.org/10.1038/s41564…

Scientific Large Language Models: A Survey on Biological & Chemical Domains arxiv.org/abs/2401.14656

75 pages covering large language models for scientific text, proteins, genomes, molecules, and multi-modal inputs. Figure 3 here gives an idea of how grand in scope it is.

Check out Alex Poret 's thread on our latest work --

A great collaborative work following up on the outbreak of Burkholderia dolosa studied in my first paper of graduate school and curious cases of reversions of stop codons.