Participants in the anakinra arm had significantly higher mortality, presumably due to higher incidence of AKI. Trial was stopped after interim analysis by the safety board. Agree w/Ramon Bataller new strategies to treat ALD and AUD are needed.

.Richard Sterling MASLD and MetALD are the dominant causes of fatty liver disease in people with HIV, affecting almost half. Applying the new nomenclature resulted in minimal change in the proportion of patients with #MASLD who would have been diagnosed previously with #NAFLD .

If you are interested in MASLD and top science this is a must! Plus the Mohntains are spectacular!

Happy Republic Day! Jai Hind🙏

This was an amazing experience

The team at IU is awesome. All-stars all of them. Grateful that I get to collaborate with them

#livertwitter

Outstanding year at IU Tx! Based on OPTN data, we did 515 transplants (ranking 26th), including a programmatic record 189 livers (9th), 32 pancreas (4th), 9 intestines (4th), 56 lungs (24th), 205 kidneys (45th), 24 hearts (75th). So proud of this incredible team! IUSM Department of Surgery

Like many other transplants programs, a record highest number of liver transplants at IU Health in 2023 with 189 liver transplants. Strong work from our transplant hepatologists, surgeons, nursing teams, coordinators and many others. IU Health IUSM Department of Surgery Indiana University Gastroenterology and Hepatology

Prediction models for the relative reduction in skeletal muscle mass during periods of calorie restriction.
onlinelibrary.wiley.com/doi/abs/10.100…

Using large data to study outcomes in cirrhosis?Comorbid conditions in cirrhosis:
1⃣ are common - 44% with psych/SUD
2⃣ impact mortality
3⃣ are best measured with hospital frailty risk score
doi.org/10.1016/j.jhep…
@swethap9 Eric S Orman MD MSCR Lauren Nephew MD, MSCE Naga Chalasani Indiana University Gastroenterology and Hepatology

Incredible effort in reviewing over 2000 patient records. Interestingly, a sizable number of patients had their first diagnosis of cirrhosis during their ER visits. Swetha Parvataneni identified several important leads for next steps.

Thomas F. Imperiale, MD, of Indiana University Gastroenterology and Hepatology spoke to us about new research on the next-gen Cologuard test at #ACG2023 . Check back to watch the full video on our website GastroEndoNews.com #CRC #cancer #GITwitter IU School of Medicine

Congrats Douglas K. Rex, MD for this wonderful recognition. This celebration took place at Doug Rex Endoscopy Suite, a world class endoscopy unit of Indiana University Gastroenterology and Hepatology

New player in MASH treatment. HU6 a mitochondrial uncoupler. Great PDFF reduction in 61 days only! In coll w VCU Stravitz-Sanyal Institute for Liver Disease Rivus Pharmaceuticals Meena Bansal Juan Pablo (JP) Arab, MD  Naim Alkhouri Naga Chalasani Elliot Tapper #livertiwtter

High burden of steatosis (~ 50%) and advanced fibrosis (6%) in person living w/HIV - particularly important because this is a relatively young cohort. #HIV #nafld Rohit Loomba Mazen Noureddin, MD, MHSc

Hot off the press from Orman et al Indiana University Gastroenterology and Hepatology

Need biological approaches (MSCs, microbiome-based and novel agents) to improve outcomes in advanced cirrhosis Jasmohan Bajaj

Thirty-day readmissions are largely not preventable in patients with cirrhosis pubmed.ncbi.nlm.nih.gov/37543729/

Will be eager to read this excellent piece

The guard has changed. Thank you and farewell NAFLD, NASH and MAFLD. Welcome SLD, MASLD and MASH! Well done and thank you to the Delphi panel and the 60+ medical societies who have already endorsed. AASLD EASLnews Maru Rinella MD Phil Newsome Global Liver Institute Fatty Liver Foundation

NAFLD Article of the Week

Thanks Cheng Han Ng et al for studying this imp knowledge gap.

➡️Preventing infections, preserving kidney fx and muscle mass and glucose control may optimize.

➡️Need novel approaches - ? Umbilical cord derived MSCs, ? microbiome-based interventions

Rohit Loomba, MD, MHSc named Chief of the Division of Gastroenterology and Hepatology, University of California San Diego, a top ranked GI group in the country

Congrats Rohit Loomba. UC San Diego Health is lucky to have you as its GI chief.

Non-member registration is more than 2000USD (with VAT) to attend the Vienna ILC meeting by EASLnews. Even if you are a member and registered early, it is still expensive. Honestly, this is prohibitive for many academicians from the US to attend. Inflation is high in Europe.