Does IV contrast load cause AKI in patients with acute MI?

New RCT from JACC Journals

▶️4-center RCT in 🇮🇹
▶️550 pts with acute MI
▶️Standard vs. Reduced contrast volume for cath
▶️AKI at 48 hours was lower in the reduced volume group (16% vs. 24%) 🫘

sciencedirect.com/science/articl…

Banning smartphones in schools is good for learning and well-being.

New study of 400+ middle schools in Norway: after smartphone bans, girls had fewer mental health issues & better grades. Boys and girls were less likely to be bullied.

Smartphones belong at home or in lockers.

Retrospective validation of 5 risk-stratification tools for syncope in older adults🔧

Tools:
-ROSE
-SFSR
-FAINT Score
-Canadian Syncope Score
-Boston Syncope Criteria

▶️Single AMC in 🇨🇳
▶️n=221
▶️Highest sensitivity and NPV➡️ FAINT score and BSC

pubmed.ncbi.nlm.nih.gov/38190847/

Does acetaminophen use during pregnancy increase the risk of neurodevelopmental disorders?💊

TL;DR:
▶️Acetaminophen use during pregnancy was NOT associated with children’s risk of autism, ADHD, or intellectual disability.

jamanetwork.com/journals/jama/…

Is Alcohol Use Disorder amenable to medical therapy?🍺

Large cohort study using Medicare data in JAMA Network Open

▶️n=9834 alcohol-related admissions
▶️Meds for AUD associated with an 18%⬇️in return to hospital/death☠️ at 30 days
e.g. Oral Naltrexone

jamanetwork.com/journals/jaman…

Could ketamine reduce mortality in critically ill patients undergoing intubation?💉

Bayesian meta-analysis in Crit Care.

▶️7 RCTs and 1 PSM analysis, n=2978
▶️Ketamine vs. Etomidate
▶️83% probability that ketamine reduced mortality🏆
reuben strayer

ccforum.biomedcentral.com/articles/10.11…

Gen Z has a great deal of hidden potential. Let's unlock it. The Anxious Generation shows how.

Thanks Adam Grant

On sale 3/26. Pre-order at:
penguinrandomhouse.com/books/729231/t…

#anxiousgeneration

Do you have research findings to share with the NY Emergency Medicine community?

Consider submitting an abstract to the NY ACEP Scientific Assembly.

🚨Deadline April 1st🚨
New York ACEP NYP Columbia/Cornell Emergency Medicine Residency Columbia Emergency Medicine
Bernard P. Chang MD PhD

nyacep.org/practice-resou…

Schools Lock Up Cellphones to Keep Students Focused wsj.com/us-news/educat…

Could a single high dose of creatine improve cognitive performance during sleep deprivation? 😴

Double-blind RCT in nature
▶️15 healthy volunteers
▶️0.35 g/kg creatine vs Placebo
▶️Creatine improved cognitive performance + processing speed🧠

nature.com/articles/s4159…

Was an absolute pleasure to meet you all and learn more about your program. Appreciate the warm hospitality. : )

The countdown to #SAEM24 has begun! And with education submissions at an all-time high, we're poised to deliver our best meeting ever!

Register by Tuesday to lock in your early bird registration pricing: ow.ly/C1O550QNMBs

Association of Cannabis Use With Cardiovascular Outcomes Among US Adults in JAHA

▶️Cannabis use is associated with adverse cardiovascular outcomes, with heavier use associated with higher odds of adverse outcomes.

⬆️Coronary Disease
⬆️MI
⬆️Stroke

ahajournals.org/doi/10.1161/JA…

Could AI models detect presence of occlusion MI on 12-lead EKG better than humans? ❤️‍🩹

New retrospective study in EHJ
▶️10,500 ACS patients
▶️AI Model had AUC of 0.938 for prediction of OMI
▶️Outperformed EKG experts

academic.oup.com/ehjdh/advance-…

Another study showing the lack of benefit from Tamiflu in out-patients with Flu.💊

SRMA in JAMA Internal Medicine: 15 RCTs.

▶️No decrease in risk of hospitalization
(including in older and higher-risk pts)
▶️Increase in nausea + vomiting 🤮

jamanetwork.com/journals/jamai…

Does under-dosing of Benzos or Keppra lead to worse clinical outcomes in status epilepticus?

Single-center, retrospective study:
▶️111 adults with SE
▶️Most were under-dosed, a/w worse GOS at discharge

💡Keppra: 40 to 60 mg/kg IV💡
70 kg pt ➡️2.8+ grams

pubmed.ncbi.nlm.nih.gov/35403498/

FDA Approves First Medication to Treat Severe Frostbite

Name: Aurlumyn (iloprost)

Based on open-label RCT in NEJM

▶️47 adults with severe frostbite
▶️Three groups
▶️Fewer amputations with iloprost

fda.gov/news-events/pr…

Great team effort! Grateful to @nih for their support.