Tim Cook I think the ad would work much better if it was reversed. All the objects should be expanding out of the iPad rather than being crushed into it

made this edited version in five minutes (thanks iMovie!)

The co-lead of our study, Prof Prof Thalia Eley 💙 will be answering questions about anxiety at the Ask The Expert webinar hosted by NIHR Research NIHR CRN Greater Manchester

It'll be a good one so sign up today!⤵️

After >10 years of collaboration our paper identifying non-coding variants in a STR-AluSx1 causing Mendelian congenital hypothyroidism is out. The variants ⬆️TF binding, leading to ⬆️ expression of nearby microRNA MIR7-2 and downstream expression changes rdcu.be/dHdTQ

This is a cool result. I think its another nail in the coffin for the claims that additive models are sufficient to model regulatory DNA. It is amply clear that cooperative interactions are extensive & in this case even important for understanding variant effects.

After 20 years and 42 days, Illumina's patent covering DNA microarray normalization, clustering, and genotyping, together known as Illumina GenCall, filed on March 24th 2004, has expired patentcenter.uspto.gov/applications/1… 1/8

An absolutely incredible resource paper from multiple institutions including Lyssiotis Lab Brian Kennedy & others:
A metabolic atlas of mouse aging
biorxiv.org/content/10.110…
Metabolomics profiling of 12 organs in male & female 🐁 at five ages, showing consistent reduction in…

Want to learn more about GALENOS and how we are creating living systematic reviews to accelerate #MentalHealth research into depression, anxiety and psychosis?

Join the free Global launch events:

For Europe, the USA & Africa:
eventbrite.co.uk/e/galenos-laun…

Would any of your former students/postdocs now working in industry be interested? Gerome Breen Prof Helen L. Fisher Prof Thalia Eley 💙

Congratulations everyone! Wonderful to contribute some analyses to the paper (the drug repositioning hypothesis generating analyses) with Joni Coleman Brett Adey

Some antecedents are specific the eventual diagnosis. ADHD in childhood predicts bipolar and psychosis but not depression in adults.
#ADHD #bipolar
authors.elsevier.com/a/1iqXVY3M3i1ki

Psychoeducation that neglects the influence of bodily states and biology is only a partial psychoeducation.

We must always remember that psychology *includes* biological psychology

Vote, vote.

The government argued, when making their visa changes, that not allowing care workers to bring dependents would only cause a drop in dependents, not care workers.

First month suggests that's very much not true and, on their own analysis, is a big problem.

Recent GWAS of school grades finds genetic overlap between language ability🗣,
psychopathology🧠 and creativity🎨. Also using #ADHD summ stats from PGC Consortium
Work lead by Veera Rajagopal , Ditte Demontis, Anders Børglum, and many more!! nature.com/articles/s4159…

We included over 5 million participants from 29 countries, making this the largest and most diverse genetic study of major #depression to-date 🌏

2/n

New pre-print from the PGC Consortium #Depression Group: Multi-ancestry GWAS of depression with 685,000 cases identifies 697 independent associations, implicating known & novel drug targets.

🔗 medrxiv.org/content/10.110…

1/n

Massive thank you to more than 5 million participants & 300 investigators worldwide who made this study possible

This is the largest genetic study of #depression so far to include inviduals of African ancestry

It also underlines the under-representation of poeple living in Africa & the need for more equitable participation & funding of research globally Wellcome PGC Africa

Are you prepared to keep on campaigning and to help us #dumpthescales ?

Kate Parminter John McDonnell MP Agnes Ayton 💙 John McDonnell MP 𝙙𝙧 𝙘𝙝𝙪𝙠𝙨

Delighted to share our new meta-analysis in JAMA Psychiatry on the associations between prospective and retrospective measures of child maltreatment with psychopathology: jamanetwork.com/journals/jamap…

A fantastic team effort with Oonagh Coleman, Andrea Danese and Dr Emma Francis!