Successful open house for the VT CDD screening center VirginiaTechCDD. Here’s to more collaborations! Fralin Life Sciences Institute Virginia Tech Science VT Biochemistry

Copper-catalysed asymmetric hydroboration of alkenes with 1,2-benzazaborines to access chiral naphthalene isosteres (Nature Chemistry): nature.com/articles/s4155….

Congrats to the VTCDD poster award winners! #1 Mary Foutz Mary A. Foutz, #2 Abdullahi Jamiu, #3 Emily Krinos em. Congrats to Webster Santos Kylene Kehn-Hall labs! Special thanks to Fralin Life Sciences Institute Virginia Tech Science for support.

Our annual VT Center for Drug Discovery poster session is in full swing. Check out the amazing work of our students in Hahn Hall south atrium (12-2 pm). Virginia Tech Chemistry Virginia Tech Science VirginiaTechCDD

Check out our collaborative work with Todd Marder (Universität Würzburg #UniWürzburg) and colleagues. Organocatalytic diboration of enynes. Nice work Nicklas Buchbinder. Check it out at Chemistry. Virginia Tech Chemistry Virginia Tech Science

Preprint work with Kevin Lynch UVA Pharmacology. We developed #Spns2 inhibitors and showed efficacy in #MultipleSclerosis mouse model + no cardiac & auditory side effects. Biomarker=lymphopenia. Builds a case for drugging #Spns2 . Virginia Tech Chemistry Virginia Tech Science
biorxiv.org/content/10.110…

Your annual reminder to avoid azide reactions in DCM
#ChemTwitter #ChemSafety
pubs.acs.org/doi/full/10.10…

17 years in the making..

We are super excited to finally achieve alcohol-alcohol cross-coupling enabled by the powerful SH2 radical sorting! Great work Jerry, Nick, Jay, James, Colin and Robert. Big shout out to our collaborator Jesus from Janssen Spain.

science.org/doi/full/10.11…

Photoinduced Decarboxylative Borylation of N-Hydroxyphthalimide Esters with Hypoboric Acid (J Org Chem/Org Lett): pubs.acs.org/doi/10.1021/ac….

Terminal C(sp3)–H borylation through intermolecular radical sampling (Science Magazine): science.org/doi/10.1126/sc….

Enantio- and Regioselective Dihydroboration of Enals (ACS Catalysis): pubs.acs.org/doi/10.1021/ac….

Check out Nicklas Buchbinder & Rose Campbell's paper in ACS Med Chem Lett ACS Publications Bio & Med Chem Content. New class of 3-Substituted-2(5H)-Oxaboroles as antifungal agents. Collaboration work with Mevers Lab. Congrats to all 🙌 Virginia Tech Chemistry pubs.acs.org/doi/10.1021/ac…

Check out this ChemRev about boron in medchem from Webster Santos Marvin Soriano-Ursua and colleagues. spearheaded by Robert Justin Grams. 👏 Virginia Tech Chemistry

I am happy to share that our B-masking strategy for the synthesis of unsymmetrical Diboron(4) reagents is now on ChemRxiv . Congratulations 🎊 to Nadim Eghbarieh for this work💙
chemrxiv.org/engage/chemrxi…

Congrats to Webster Santos PhD #28: Dr. Christopher Shrader. He is an #S1P transporter #Spns2 drug hunter. Great work 🙌 Virginia Tech Chemistry Virginia Tech Science

Postdoctoral Fellowships in Pandemic Prediction and Prevention (PPP) at Virginia Tech

The PPP Destination Area (DA) project is a major initiative supported by the Office of the Provost. We seek highly qualified and motivated post-doctoral candidates in a wide number of areas:

Review: Evolutionary enigmas of the (glyco)sphingolipid biosynthetic pathway buff.ly/3Ov2zJk (BBA)

Organocatalytic Decarboxylative Borylation of Cyclopropane N-Hydroxyphthalimide Esters (J Org Chem/Org Lett): pubs.acs.org/doi/10.1021/ac… (@DrGregor2).

Boryls, Their Compounds and Reactivity: A Structure and Bonding Perspective (Xueying GUO): pubs.rsc.org/en/content/art… (@ChemicalScience).

Catalytic Regio- and Enantioselective Boracarboxylation of Arylalkenes with CO2 and Diboron (J. Am. Chem. Soc.): pubs.acs.org/doi/10.1021/ja….