This #ReviewedPreprint makes use of AlphaFold2 to predict the models of tens of cohesin subcomplexes from different species. elifesciences.org/reviewed-prepr…

Amazing talks this morning regarding #AI and #Alphafold2 in #Biotrans 🧬

Antonio Chaves-Sanjuan Imaging_Artifact Have you tried Omokage search by PDBj?
pdbj.org/emnavi/omo-sea…
It only searches against experimental structures and not AlphaFold2 predicted structures though.

Gemma C Atkinson AlphaFold2?

Get ready, adventurers! #Menyr closed beta is just around the corner. Don't miss your chance to join the thousands of #ttrpg enthusiasts in this thrilling adventure. Secure your access now at kickstarter.com/projects/nogst… and be among the first to jump in the beta. See you in Menyr!

AlphaFold2 can predict single-mutation effects on structure and phenotype biorxiv.org/content/10.110…

#カガク 。 #生体分子 。 #AI 。AlphaFold/AlphaFold2/RoseTTAFold。“ Foldseek ”。Nature Technology Feature“Foldseek gives AlphaFold protein database a rapid search tool” nature.com/articles/d4158…

Check our latest work about AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design by Guillem Casadevall Cristina Duran
Silvia Osuna in JACS Au

iqcc.udg.edu/wordpress/2023…  

#IQCCpaper #openaccess TCBioSys

AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design pubmed.ncbi.nlm.nih.gov/37388680/?utm_…

#Alphafold2 on Colaboratory repeatedly disconnecting for no obvious reason after 5 hours on an A100 instance is not only super annoying but also quiet pricey! Anyone got a good step by step instruction for a local installation?

Fascinating read! RNA-guided endonucleases are present in all three domains of life! And happy to see how AlphaFold2 sheds light on the structure of SpuFz1 in complex with ωRNA-target DNA!! 🧬🔍 #ResearchBreakthrough #AlphaFold #CRISPR

'Discovery of deaminase functions by structure-based protein clustering'
Huang J, Lin Q, Fei H, He Z [..] Zhao KT, Gao C.
Cell 2023-06-27.
doi.org/10.1016/j.cell…
#CRISPR ; AlphaFold2; single-AVV packaging CBE

John Jumper from ⁦Google DeepMind⁩ describes AlphaFold2.

today Alex TwentySeven(@univ_paris_cite,Inserm_EN,Université de La Réunion) is happy to present his work on 'An agnostic analysis of the human AlphaFold2 proteome using local protein conformations' at Jobim2023 (on the left results, on the right thinking Snoopy)

RaptorX-Single not only runs much faster than MSA-based AlphaFold2, but also outperforms it on antibody structure prediction, orphan protein structure prediction and single mutation effect prediction.

🎨 #Art and #Architecture 🕌

youtu.be/ZOm7hAaMaY4

This is where the recent advancements in 3D protein structure prediction tools, such as Alphafold2, have been transformative.

アミノ酸の配列調べようと持ったらAlphaFold2での推測した３次元構造見られる様になっていてびっくりした

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Improvement of protein tertiary and quaternary structure predictions using the ReFOLD refinement method and the AlphaFold2 recycling process Recep Adiyaman, PhD, Nicholas Edmunds, Ahmet G Genc, Shuaa M A Alharbi, Prof. Liam McGuffin in Bioinformatics Advances
doi.org/10.1093/bioadv…

Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…

バーチャルスクリーニングに適したAlphaFold2タンパク質立体構造モデルの選択
M1内河さんの発表です。

RaptorX-Single not only runs much faster than MSA-based AlphaFold2, but also outperforms it on antibody structure prediction, orphan protein structure prediction and single mutation effect prediction.

Interested in #AlphaFold ?
Don’t miss Ron Vale’s #LMBSeminar on Monday 17th July at 4PM (BST). Ron is Executive Director at HHMI | Janelia and will be discussing ‘AlphaFold2 as a Tool for Cell Biology.’
More details: www2.mrc-lmb.cam.ac.uk/news-and-event…