Come join us in Oxford as an Associate Professor in Molecular and Cellular Biochemistry.
We are considering a wide range of research areas, but I would note that we have a vibrant chromatin and gene regulation community.
Happy to answer questions if you are interested.
Please RT!

New Review: 'Chromatin dynamics and RNA metabolism are double-edged swords for the maintenance of plant genome integrity' rdcu.be/dFJxH

chromatin material of chromosome see in the video how it be made of
#سوسن_القاضي
#gntm
#แบนตึกส้ม

The splicing regulators RBM5 and RBM10 are subunits of the U2 snRNP engaged with intron branch sites on chromatin dlvr.it/T5kXZS

From multiomics of liver samples to CRISPR screens to extensive funcional validation (KO experiments, genome-wide chromatin profiles and spatial tx)

We demonstrate that the transcription factor ZNF469 regulates collagen production in liver fibrosis

biorxiv.org/content/10.110…

#GIPath classic
HSV esophagitis
Remember the 3 Ms of HSV:
Ⓜ️ultinucleation
Ⓜ️argination of chromatin (glassy nuclei)
Ⓜ️oulding of nc
When you 👀 esophageal ulcer check for infection
HSV affects keratinocytes (check ulcer edge, superficial layers)
CMV freq affects endothelium,…

Lovely work from Bethany Bartlett showing the role of the nuclear pore basket in formation of cytoplasmic chromatin fragments & activation of innate immune sensing in senescence. biorxiv.org/content/10.110…
MRC_HGU Institute of Genetics and Cancer Juan Carlos Acosta

Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape dlvr.it/T5lQZh

⁦Mathieu Lupien⁩ kicking off day 2 #embochromatinbio24 discussing chromatin variants in cancer

p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response

Nat Commun (April 1, 2024) doi.org/10.1038/s41467…

Congratulations to Mélanie Hamon melanie hamon! Her project ‘ChromaBac – Bacteria driven chromatin modifications in health and disease’ is among the first laureates of the 'Chaires d'Excellence' 👏👏

The @CEI-FCCC #NEXTepiGEN seminar series featuring #AssistantProfessors leading the future for #epigenetics and #chromatin field is today. Jean-Paul Armache from Center for Eukaryotic Gene Regulation at PSU showed amazing #CryoEM for chromatin enzymes! A great talk Fox Chase Cancer Center @CEI-FCCC

Thanks for visiting us!

Our May 2024 issue is now live: go.nature.com/3xBgpEw
Topics include: evolutionary of the meiotic recombination machinery; guidelines for omics benchmarking; chromatin remodellers in development and disease; genomics for biodiversity conservation

Deborah Bourc’his on chromatin regulation of retro transposons #ICTE2024

I owe Dan Dennett, who passed away, my career.
His majestic oeuvre, Consciosness Explained, has this hysterically funny passage (VERY worth reading).
I read it as a grad student, decided against moving to neurobiology, and stayed in chromatin.

Meet Cigall Kadoch of @HarvardMed who knows everything about Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Disease. And guess what? You can hear all about it at our 60th Anniversary Symposium! #MPIMG60years Register now👇
molgen.mpg.de/60th-anniversa…

OpenAnnotateApi: Python and R packages to efficiently annotate and analyze chromatin accessibility of genomic regions academic.oup.com/bioinformatics…

Join us for this year’s “Transcription and Chromatin UK” meeting in Newcastle! Biochemical Society

Exciting new research from our lab published in @ProteinScience ! We unraveled the mechanisms of proteasome-mediated degradation of histone H1, a key player in chromatin organization: doi.org/10.1002/pro.49…… #ChromatinBiology #ProteinDegradation #HistoneH1