Summary of IL-23 Revolution

▪️RZB > UST for Crohn’s
▪️Note difference of RZB induction dose
▪️MIR approved for UC - coming for CD
▪️MIR not superior to UST 🧐
▪️GUS for UC induction ✅
▪️GUS for CD data coming
▪️Combo IL-23 + TNF/JAK1 is promising!

🙏Dr. Marla Dubinsky

#EBMed

Diagnosis of C. difficile infection

▪️Understand what you are ordering
▪️2 assays are better than 1
▪️At least 1 should include the ElA
▪️The other can be GDH or PCR
▪️If the GDH used & results are discordant, then reflex to PCR to confirm the diagnosis!

#EBMed

Treatment Algorithm for Managing C. difficile infection in 2024

1️⃣ 1st Episode
2️⃣ 2nd Episode
3️⃣ 3rd Episode

▪️Fidaxomicin > vancomycin
▪️Look for risk factor - use BEZ
▪️Use Microbiota replacement therapy (MRT)

🙏Dr. Paul Feuerstadt

#EBMed

Evaluation of Symptoms Suspicious for GERD - Value of Endoscopy

⭐️Assess integrity of EGJ ⭐️

Several pitfalls of Hill classification!

Consider using 🆕 AFS Endoscopic Classification of the Esophagogastric Junction Integrity!

🔗 journals.sagepub.com/doi/full/10.11…

🙏Dr Gyawali

#EBMed

Diagnostic Approach Based on Symptoms Suspicious for GERD

▪️Heartburn, regurgitation, esophageal CP
▪️Belching
▪️Chronic cough, asthma
▪️Hoarseness, globus, n, abd pain, dyspepsia

Categorize symptoms:
1️⃣typical
2️⃣atypical

Symptoms ➡️ Likelihood!

🙏 Dr. Gyawali

#EBMed

Common Mistake for C. difficile injection

⭐️Not considering bezlotoxumab as a treatment option⭐️

Prevents recurrence! Use if >2 RF

Note: do not use in heart failure patients!

See Risk Factors
▪️Demographic
▪️Exposures
▪️Environment

🙏Dr. Paul Feuerstadt

#EBMed

Step-up vs Step-down Elimination Diet for Eosinophilic Esophagitis

▪️Step-up makes sense
▪️Especially, EoE ➡️ ❌🦀
▪️Start with SINGLE food or TWO food
▪️If ❌ response, FOUR food
▪️Then consider SIX food
▪️6 weeks for each

🔗 gastrojournal.org/action/showPdf…

🙏Joan Chen, MD MS

#EBMed

Thank you Evidence-Based GI Doc Linda Ánh Vân Nguyễn MD Aline Charabaty, MD, FACG, AGAF and everyone at #EBMed for an incredible 1st Great #GI Debates!

Reasons you must attend next year!

🤣Laugh so hard you’ll cry
🎤Mic drop worthy debates
🎶Epic music walk-ons
🏖️Bonding beach activities
🫶🏾Mentorship from world experts

Response to Proton Pump Inhibitors (PPI)

Syndrome correlates with NNT

▪️Uninvestigated heartburn: 2.2
▪️Heartburn w/o esophagitis: 3.7
▪️Heartburn + esophagitis: 2.1
▪️Erosive esophagitis: 1.8
▪️Regurgitation: 5.6
▪️Chronic cough: 11.4
▪️Laryngeal symptoms: 79.2 🤯

#EBMed

Truly and tremendously enjoyed today, grateful for the small group! So many direct opportunities to learn from the giants outside of my institution. Feeling pumped 💪and inspired.
Rukaiya Bashir Hamidu, MD || Rukkss!! Joseph Sleiman, MD Bincy Abraham, MD, MS Katie Dunleavy
#EBMed

Recap of the first #EBMED great GI debates!

📊 #EBGI debates with a lot of 🤣
🙌 inclusive of physicians at all career levels
🏝️ Mentorship and activities by the 🌊

Thank you to Evidence-Based GI Doc, Linda Ánh Vân Nguyễn MD and Aline Charabaty, MD, FACG, AGAF for this wonderful opportunity! Cant wait for next year!

Woke up with this view to kick off #EBMed conference ☀️🌴😍. Ready for some learning and fun debates!
And yes, swag included SPF🧴😎

Dynamic and engaging talk by Brennan Spiegel, MD, MSHS #EBMed #evidenceispower

Excited to see rising ⭐️ #IBD fellow at Mayo Clinic Gastroenterology & Hepatology Priscila Santiago, MD present a case of Acute Severe UC as early career faculty at #EBMed

Fantastic to hear the opinions of @Dr. Samir A Shah, Dr McCutchen & Dr Novak on first choice for advanced therapy based on pt personalization

Loved this format. What a great way to learn. Thanks #EBMed and Dr. Phil Schoenfeld for the opportunity. #EBMed sGreatGIDebates. NM Gastroenterology & GI Surgery

#EBMED guiding us through evidence-based management of esophageal disorders‼️

See 👀 anything familiar ⬇️

Follow Evidence-Based GI: An ACG Publication (EBGI) here 👉🏾 GI.org/ebgi to keep up to date on new studies 📚 and trends 📈in GI ‼️ #EBGI

Kicking off #EBMed Inaugural Great GI Debates!

Thank you, Esophagus group, for adopting me for this meeting!!

Thank you Evidence-Based GI Doc, Linda Ánh Vân Nguyễn MD, Aline Charabaty, MD, FACG, AGAF and everyone else who helped/contributed to this outstanding conference!! Engaging, educational, inspiring and fun experience and I can’t wait for the next one! #evidenceispower #ebmed #girocks

Treatment Algorithm for Managing C. difficile infection in 2024 - Carl Kay, MD
Uniformed Services University

#ClostridiumDifficile #Cancer #Fidaxomicin #Microbiota #BacterialInfection #OncoDaily #Oncology #TreatmentAlgorithm #Vancomycin #EBMed

oncodaily.com/55064.html

An absolute privilege to share the #EbMed stage with About IBD: Amber-Writer, Journalist, Podcast Host ! Partnering w advocates have changed how I approach #IBD care, contributed to my growth as a person & as an MD ! Plus, I have learned so many tips & tricks from advocates that I share w my own clinic patients !