Amazing session on FLT3 m AML.
Heme Reports

Crenolanib and Intensive Chemotherapy in Adults With Newly Diagnosed FLT3-Mutated AML | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…

Gilteritinib as Post-Transplant Maintenance for Acute Myeloid Leukemia With Internal Tandem Duplication Mutation of FLT3 | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…

6/ We first demonstrated that only two FLT3LG transcripts encode a functional isoform (able to induce FLT3 phosphorylation): the canonical transmembrane (mFL) and a constitutively secreted (sFL) forms.

So important to understand the physiology of FLT3

1/ FLT3L, encoded by the FLT3LG gene, is a hematopoietic growth factor. Seminal mouse work demonstrated that it is crucial for dendritic cell, NK cell, and B cell development, but not other lineages, including monocytes doi.org/10.1182/blood.…

Azacitidine, Venetoclax, and Gilteritinib in Newly Diagnosed and Relapsed or Refractory FLT3-Mutated AML | Journal of Clinical Oncology ascopubs.org/doi/abs/10.120…

تبارك كلية الطب للطبيب المقيم طلال عبدالله المعجل فوز بحثه بعنوان:
CD99 IHC Expression in AMLs with FLT3 Mutations
بالمركز الثاني في جائزة مسابقة الملصقات العلمية لمؤتمر 'أحدث التطورات والابتكارات في المختبرات الطبية' الذي نظمه مختبر البحث المركزي مختبر البحث المركزي لجامعة الملك سعود مع مركز الخدمات…

自分は急性骨髄性白血病FLT3-ITD変異を高頻度に有しているタイプで
この遺伝子変異を有する場合は予後不良群に該当します
長期生存率低くまた再発リスクも高いです
主治医の先生もあまりみたことがないくらいとおっしゃっていました

でも負けるわけにはいかないんだ！
少しでも長く生きたい！

FLT3公演目、公演最後、王たちが上手来たときに、もっふんで手を降ったら、hrkwさんが殿の袖からこんにちはして、手振もふもふしたの嬉しかった。他の人のためで流れ弾だとしても嬉しかった。

この感動をもう一度……と思うけどもうないのよな。

We're thrilled to announce the publication of groundbreaking research on narazaciclib and its anti-AML activity in preclinical models with specific AML mutations of clinical significance.

➡️ bit.ly/4b7ADVy

#OncologyResearch #DrugDevelopment #AcuteMyeloidLeukemia

Measurable Residual FLT3 CD135 Internal Tandem Duplication Before Allogeneic Transplant for Acute Myeloid Leukemia | Hematology | JAMA Oncology | JAMA Network jamanetwork.com/journals/jamao…

明日のキングオージャーFLT3公演、干そうかな。名古屋今月いったばかりだし、静岡見てるし大阪あるし、身体ダルいし。

Study from NIH CIBMTR has shown that 1 in 3 adults in first clinical remission from FLT3-ITD acute myeloid leukemia had persistent FLT3-ITD detectable in blood prior to allogeneic transplant, associated with higher post-transplant relapse and death. ja.ma/3Ul4hzn

👉👉👉Please join us today ! The latest episode of Heme Reports features AML experts Naval Daver, M.D. Jessica Altman, MD Eunice Wang MD &Dr. Sasha Perl who join us: #FLT3 -m AML Vincent Rajkumar Sanam Loghavi, MD صنم لغوی 🔬🧬 Shematologist, MD Naveen Pemmaraju, MD

April 30, 2024, 6:30 PM CT

Register: bit.ly/3xRhUOX

Season 2, episode 4 of Heme Reports tonight… with leading AML experts Naval Daver, M.D. Jessica Altman, MD Eunice Wang MD Dr. Sasha Perl.
We will discuss FLT3 m AML & hope to cover revised risk stratification, implications for transplant, combination therapies, new FLT3i approvals, the…

ascopubs.org/doi/abs/10.120…

Amazing discussion tonight on AML with mutated FLT3! Already looking forward to the next discussion!

kenken 返信ありがとうございます。うちの娘も同じFLT3陽性で、抗がん剤治療で一時減少したが、すぐに白血球が上がってしまい、ゾフパタ治療でした。移植絶対だったので、移植したばかりです。