(3/4) NSW COVID-19 Whole Genome Sequencing: Week ending 27 April 2024

🔹JN.1 dominates sub-lineages circulating in the community.

🔹BA.2.86: 160 sequences (unchanged)

GISAID: gisaid.org/hcov19-variant…

NSW Health #GenomeSequencing

Top 5 SARS-CoV-2 lineages for Apr 2024 in Canada:

JN.1 (31.67%)
JN.1.4 (16.17%)
JN.1.7 (9.28%)
KP.2 (7.85%)
KP.3 (7.75%)

The number of submitted sequences has gone *way* down to just 1045, down from 12,385 in Dec 2023
Source: GISAID

◾ JAPÓN 🇯🇵
▪️ PREFECTURA DE MIYAGI.

El Instituto de Salud Pública y Medio Ambiente de la Prefectura de Miyagi cargó❗21❗secuencias DERIVADAS DE ⚫JN.1 a GISAID desde Miyagi, Japón.
x.com/HNimanFC/statu…

NZDSOS - NZ Doctors Speaking Out with Science NZ and the MRNA We all know why the H5N1 'virus' data is not available on the WHO's own database, GISAID, and GenBank. They are still in the process of inventing it. SCV2 and C19 still, to this day, exist only in these databases. Be prepared to be 'told' you have H5N1.

◾ IRLANDA 🇮🇪
▪️ DUBLÍN.

St. Vincent's Microbiology cargó❗37❗secuencias DERIVADAS DE ⚫JN.1 a GISAID desde Dublín, Irlanda.
x.com/HNimanFC/statu…

Rick Bright GISAID Initiative pubmed.ncbi.nlm.nih.gov/37812908/

#東京都 #変異株
・JN.1: 66.8％
・「組み換え体」：31.3% ⬆️⚠️
組み換え体の中身はGISAIDデータも参考にするとXDQ(BA.2.86.1とXBB亜種の組み換え体)の仲間の可能性が高そうです。
XDQ及び亜種の感染性や免疫逃避性を含め、今後の動向に要注意です💡
#メタコビ covid-data.jp

GISAID Initiative Thanks to all the countries that are still supporting #SARSCoV2 testing & rapidly submitting seqs to
GISAID Initiative

Top submitters: #USA #Canada #UK #China #Australia #SouthKorea #Japan #Ireland #Taiwan #Russia #Spain #PuertoRico (USA) #France #Germany #Sweden #Ghana #Netherlands

Came down with the worst flu I've ever experienced this week. Found out from GISAID Initiative we've been registering H5N1 cases in humans and cattle here in the US? That is bad news.

◾BRASIL 🇧🇷

El Instituto Evandro Chagas subió❗38❗secuencias DERIVADAS ⚫JN.1 a GISAID desde Brasil.
x.com/HNimanFC/statu…

◾ ESTADOS UNIDOS 🇺🇸
▪️ CONDADO DE SONOMA, CALIFORNIA.

El Laboratorio de Salud Pública del Condado de Sonoma cargó❗20❗secuencias DERIVADAS DE ⚫JN.1 a GISAID desde el Condado de Sonoma, California, EE. UU.
x.com/HNimanFC/statu…

◾Seguimiento ⚫JN.1*
( JN.1 y sus derivados JN.1.1, JN.1.2, JN.1.16, KP.1, KP.1.1, KP.2, etc.)

◾Lunes 29 y Martes 30 de Abril de 2024.

◾ RESUMEN

◾ARGENTINA 🇦🇷

El Instituto N.E.I. CGMalbran subió❗68❗sec. DERIVADAS ⚫JN.1 a GISAID desde Argentina
x.com/HNimanFC/statu…

#H5N1 Updates

PB2 Mutation Profile of all the uploaded H5N1 Clade 2.3.4.4b sequences in GISAID Initiative in 2024 | #USA

Note: Includes all H5N1 Clade 2.3.4.4b sequences uploaded in GISAID with submission dates on or after 1/1/24

Filter by Species/State/Year

public.tableau.com/app/profile/ra…

David Joffe PhD, FRACP 🇦🇺 Their variant categorisation seems out-of-date. The data I got from GISAID does suggest JN.1 was still just holding on, but about to be swamped.

The leading challengers seem to be KP.3 (FLiQE) at 18% and JN.1.32 (FLiTI) at 16%, which is interesting.

KP.2 leads the FLirTS at 6%.

GISAID Initiative You can filter spike mutations R346T, L455S, F456L, T572I (Top convergent mutations) to display #SLip , #FLiRT , #TiRT , #FLiRT TI combo mutations; (Note: retired #FLip as of now)

4/n

It is relatively well know that Ralph Baic and Peter Daszak's C19 exists as a virtual creation in the GISAID and GenBank databases. The $1M for a single particle isolate of C19 has still not been claimed. WHO argues it is not measurable while advocating rt-PCR, RaT, and LFT tests

◾ JAPÓN 🇯🇵
▪️ PREFECTURA DE EHIME.

El Instituto de Salud Pública y Ciencias Ambientales de la Prefectura de Ehime cargó❗2❗secuencias DERIVADAS DE ⚫JN.1 a GISAID desde Ehime, Japón.
x.com/HNimanFC/statu…

GISAID Initiative Predicted Immune Escape vs ACE2 Binding Scores of circulating SARSCoV2 lineages (Relative to BA.2)

Closely looking at JN.1* with #FLiRT mutations (S:R346T & S:F456L), KP* & recently designated LB.1

public.tableau.com/app/profile/ra…

3/n

◾ MALASIA 🇲🇾

El laboratorio de salud pública Kota Bharu cargó❗21❗secuencias DERIVADAS DE ⚫JN.1 a GISAID desde Malasia.
x.com/HNimanFC/statu…