📢Open Ph.D. Positions!!🙂
Interested in understanding GPCR Mediated Regulation of Metabolic Disorders!!
#Liver #MAFLD #MASH #HepaticFibrosis #GPCRSignaling BSBE@IITK
Applications invited for Ph.D. Walk-in Interview at BSBE IITK. Last Date for Application- 20th July 2023.

In our Neuroendocrinology course this week, we put the students’ artistic skills to the test. #GPCRsignaling #UAMS Gwen V. Childs 🎨 🔬

📢 We are hiring!
Interested in GPCR Signaling and Liver Metabolism? We have multiple open positions- JRF and PDF! 😃
Visit our lab webpage for more information
shanujain07.wixsite.com/liver-metaboli…

#GPCRsignaling #LiverMetabolism #NASH #Fibrosis

Online now - the Review 'Beneath the surface: endosomal #GPCRsignaling ' from Emmanuel Flores-Espinoza and Alex Thomsen.

#endosomalsignaling #desensitization #internalizedGPCRs #megaplexes

Read it free for 50 days 👉 authors.elsevier.com/a/1iyNV3S6GfQZ…

Andrej Sali lab and Bridget Carragher highlight a star-studded lineup of speakers for the conference on GPCRs. Time to register for this fall's meeting in Santa Fe, NM, USA at hubs.la/Q02q-FQl0 #biologyconferences #GPCRs #GPCRSignaling #GPCRfunction #drugdiscovery #drugdevelopment

New work highlights a role for GRKs in location-biased #GPCRSignaling and demonstrates the complex interactions between ligands, GRKs, and cellular location that contribute to #BiasedSignaling .

Learn more: scim.ag/5Vv Sudarshan Rajagopal Trinity College at Duke

Research from Babraham Institute sheds light on how a critical intracellular GPCR effector is activated in neutrophils and emphasizes the importance of studying signaling pathways in physiologically relevant contexts. #GPCRSignaling fcld.ly/sj93avd

📢Interested in GPCR Signaling and Liver Metabolism! We have an opening for a JRF position😃
Send your CV to [email protected]
🐁Prior experience with mouse models is a plus but not required. #GPCRsignaling #LiverMetabolism #NASH #Fibrosis

The Marin and Chaumont-Dubel groups at Inserm demonstrate how #GPCR interactome dynamics can control highly coordinated cellular processes such as dendritic tree morphogenesis. #GPCR Signaling fcld.ly/7sbufz8

Characterizing over 350 mutant forms of the GPCR AT1R, Laporte lab and The Vaidehi Lab interrogate structural features of this cardiac receptor and identify residues that contribute to #allosteric regulation communication pathways. McGill University #GPCRSignaling scim.ag/3Ha

Inhibition of vesicle exocytosis and neurotransmitter release by presynaptic G-beta-gamma is critical for behavior and neurological processes in mice Vanderbilt University #GPCRSignaling stke.sciencemag.org/lookup/doi/10.…

Researchers find that proteins governing the signaling functions of #CCR2 aren’t involved in the receptor’s scavenging function—hinting that signaling and scavenging CCR2 populations could be targeted independently. UCSD BioSciences #GPCRSignaling scim.ag/1oA

Inactive conformations of related GPCRs are structurally similar, but exhibit distinct ligand-binding properties Institute for Molecular Bioscience #GPCRSignaling stke.sciencemag.org/lookup/doi/10.…

Parkar and colleagues discover a G protein-biased compound that can sustainably activate S1P1 and preserve endothelial function without compromising immune responses in rodents. Sanofi #GPCRSignaling #BiasedAgonism fcld.ly/mhvngtn

Credit: Val Altounian/PDB

Biased allosteric modulators of the M1 muscarinic acetylcholine receptor demonstrate that phospholipase D controls neuronal functions, shows a new study from the Conn group at Vanderbilt School of Medicine Basic Sciences. #GPCRSignaling stke.sciencemag.org/lookup/doi/10.…

New sensors alert! #gpcr #drgpcr #gpcr signaling
Thanks to Bryan Roth et al.

The Maestro Z makes your #assays simple, so you can focus on the science.

Use the Maestro Z system for your next assay:
#Virology
#Immunooncology
#Cytotoxicity
#CellMigration
#CellProliferation
#GPCRsignaling

youtube.com/watch?v=Hz1HAZ…

#MaestroZApp #CancerResearch #CARTcell

Pay with a Tweet Wednesday PPT download: RhoA regulation scienceslides.com/5mBY #signaling #ecadherin #gpcrsignaling #calcium #rap1

Pay with a Tweet Wednesday PPT download: LPA signaling cascades scienceslides.com/5sIT #signaling #ras #pka #gpcrsignaling #calcium

Researchers have discovered that spatial bias in cells can influence biological outcomes from parathyroid hormone – a finding that could facilitate the design of new and more precisely targeted drugs. PittDeptofMed #GPCRSignaling #MechanismMatters fcld.ly/4tbtpyf