PGC Consortium(@PGCgenetics) 's Twitter Profile Photo

New pre-print from the PGC Consortium Group: Multi-ancestry GWAS of depression with 685,000 cases identifies 697 independent associations, implicating known & novel drug targets.

🔗 medrxiv.org/content/10.110…

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New pre-print from the @PGCgenetics #Depression Group: Multi-ancestry GWAS of depression with 685,000 cases identifies 697 independent associations, implicating known & novel drug targets.

🔗 medrxiv.org/content/10.110…

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Dr. Sheridan Littleton(@sciencesheri) 's Twitter Profile Photo

My functional validation of a causal variant at the FAIM2 obesity GWAS locus is out today in Cell Genomics! (1/4) cell.com/cell-genomics/…

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SciencesNetwork(@SciencesNetwork) 's Twitter Profile Photo

:
pubmed.ncbi.nlm.nih.gov/38693319/
pubmed.ncbi.nlm.nih.gov/38634511/
pubmed.ncbi.nlm.nih.gov/38548025/
pubmed.ncbi.nlm.nih.gov/38538956/
pubmed.ncbi.nlm.nih.gov/38480934/
pubmed.ncbi.nlm.nih.gov/38460828/
pubmed.ncbi.nlm.nih.gov/38423513/
pubmed.ncbi.nlm.nih.gov/38422475/
pubmed.ncbi.nlm.nih.gov/38363735/
pubmed.ncbi.nlm.nih.gov/38310758/

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PGC Consortium(@PGCgenetics) 's Twitter Profile Photo

We also have sex-specific GWAS summary statistics 🚺🚹, thanks to the work lead by Dr Joanna Martin: biologicalpsychiatryjournal.com/article/S0006-… Data download is here: figshare.com/articles/datas…

We also have sex-specific GWAS #ADHD summary statistics 🚺🚹, thanks to the work lead by @joannamphd: biologicalpsychiatryjournal.com/article/S0006-… Data download is here: figshare.com/articles/datas…
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Nikee Shrestha(@NikeeShrestha2) 's Twitter Profile Photo

Schnable Lab student Harshita giving a lightning talk about her project on using GWAS and TWAS for finding flowering genes in sorghum!

Schnable Lab student @Harshita17_ giving a lightning talk about her project on using GWAS and TWAS for finding flowering genes in sorghum!
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Tau-Mu Yi(@socalsysbio) 's Twitter Profile Photo

Excellent critique of GWAS. As a molecular (systems) biologist, critique 1 has always resonated with me. As I have learned more human genetics to teach my class, I have become worried about critique 2.

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Plaid Cymru 🏴󠁧󠁢󠁷󠁬󠁳󠁿(@Plaid_Cymru) 's Twitter Profile Photo

Mae ethol Comisiynydd Heddlu Plaid Cymru yn golygu ethol gwas cyhoeddus gweithgar sydd wedi'i wreiddio yn y gymuned - un sy'n gweithio i Gymru, nid San Steffan

Pleidleisiwch Blaid Cymru ddydd Iau

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Sasha Gusev(@SashaGusevPosts) 's Twitter Profile Photo

But even one threshold has been highly effective. In the early days, GWAS and candidate gene studies were rife with false-positives [Hirschhorn 2002]. After genome-wide significance, GWAS associations for quantitative traits replicate at a remarkable 94.8% [O’Sullivan 2021].

But even one threshold has been highly effective. In the early days, GWAS and candidate gene studies were rife with false-positives [Hirschhorn 2002]. After genome-wide significance, GWAS associations for quantitative traits replicate at a remarkable 94.8% [O’Sullivan 2021].
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