PKM2

#Leica #ライカ #imaimachi #今井町 #オールドレンズ
M10 + K&F KF-PKM2 + smc PENTAX-M 50mm f1.7
レンズのテスト。NOKTON 50mm F1.2の方が、立体感や後方のボケの綺麗さは上かも。

🚨Last weeks #immunometabolism discoveries Bims: Biomed News ⬇️⬇️⬇️

biomed.news/bims-imicid/20…

Highlights:

I) QUAS-R for single cell glutamine uptake profiling
II) PKM2 in neutrophils
III) Enhanced γδ T cell metabolic flexibility improves anti-tumour cytoxicity

beres juga pkm2 tai babi

Interesting work from Markus Hafner on pre-mRNA G4 interactions with PKM2

Acontece no dia 29 de abril, às 12h, o webinar “Potential Immune Modulators? Development of Novel Synthetic Compounds as Inhibitors of PKM2 and CRM1 for Cancer Treatment”, que será ministrado pelo pesquisador Bruno Kaufmann Robbs (UFF).

Participe em: zoom.us/j/97489200451?…

Pesquisa investiga o papel da enzima metabólica PKM2 na modulação da resposta imune de neutrófilos: mla.bs/ec5df52c

Center for Research in Inflammatory Diseases(CRID) Juliana Escher Toller Nature Communications

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Switch Akko Jellyblack lubed 250g0,105 +
everglide aquaking 62g factory lubed +geteron milk yellow lubed krytox pkm2

Keycap honey milke xda profile

PKM2 functions as a histidine kinase to phosphorylate PGAM1 and increase glycolysis shunts in cancer
embopress.org/doi/full/10.10…

Speaker 1 for Friday's Immunometabolism Forum (IMF@Global) is Juliana Escher Toller (@EscherToller), a Postdoc from Luke O'Neill lab in TCD TBSI TCD Biochem & Immuno Trinity College Dublin
She works on #Neutrophils #PKM2 #Immunometabolism -> #VeryExciting 😁

Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis frontiersin.org/articles/10.33…

Yavuz et al explore PKM2's role in #glioblastoma . High expression was an independent predictor of worse survival, suggesting it's role as potential target for anticancer treatments in radiotherapy-treated #gliobalstoma patients.
link.springer.com/article/10.100…

Congratulations to Dariia, PhD student at Ben-Gurion University of the Negev, who won the BioFactors Award for her poster on acetylation of PKM2 at #Enable2023 ; presented by IUBMB President Alexandra Newton.

Wiley Biomedical Science FEBS ENABLE Conference

AMPK and PKM2 define metabolic function of adipose tissue, hepatic and splenic tissue iNKT cells

MTG - SALVA-ME X DENTRO DA EVOQUE - RBD Feat.R10 O PINTA de DJ PKM² | O FAMOSO BIRULEIBY na #SoundCloud
on.soundcloud.com/zBEADe3FsEPLYT…

N6-isopentenyladenosine inhibits aerobic glycolysis in glioblastoma cells by targeting PKM2 expression and activity

➡️ buff.ly/3vx3u5V

#CancerMetabolism #PKM2 #BrainCancer

Recent study by Yavuz et al. found that high pyruvate kinase M2 (PKM2) expression in #glioblastoma patients undergoing radiotherapy is independently linked to poor prognosis, suggesting it as a potential therapeutic target.
Read more about it here: link.springer.com/article/10.100…

And another collaborative publication!
'PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2'
pubmed.ncbi.nlm.nih.gov/38822524/

With pleasure I share a recent paper from my lab spearheaded by former PhD student Mohaned Benzarti ! Unexpectedly, we observed a strong block of #PKM2 under low (instead of high) rates of glycolysis which we modeled with galactose.

cell.com/cell-reports/p…

Article✍️Targeting #PKM2 signaling cascade with #salvianic #acid A normalizes #tumor #blood #vessels to facilitate #chemotherapeutic drug delivery. From Dr. Zhao @NanjingUniversityofChineseMedicine; Elsevier Pharma.
sciencedirect.com/science/articl…