Grateful for 3⃣ opportunities to present our work at the #ICCR2023 #Montreal meeting (& for 1 travel award🙏)

This year we are all over #RTdrugcombo screens at #ICRR2023 & #ASTRO23 . Fascinating landscape of radiosensitizing drug effects across 3D tumor models🎯 #radbio #genomics

Viewpoint is in press!

Maybe 2020 wasn't a terrible year in every way imaginable.

... because a couple drugs officially embarked on unprecedented regulatory territory. They are [successfully] being developed specifically for use with RT.🙌

#radonc #rtdrugcombo

📢Results are coming in for our 🦣 🤖screen of ☢️➕💊 combinations in a panel of 3D tumor models‼️

Stay tuned for💻data coming soon♨️

Great interdisciplinary effort in Mass General Cancer Center💪

Also collaboration with @oncoray_press & @dkfz👍

#RTdrugcombo #radbio #precisiononcology

Presenting at the #ASTRO19 Breast Cancer Poster Viewing QA on safety & efficacy of #radiotherapy w/ palbociclib

Preclinical evidence suggests synergy w/ this #RTdrugcombo , but concern over possible toxicity

We found this combo was safe!

Manuscript Link: bit.ly/2lVeGoE

Anthony Chalmers 💙 gives a very clear overview of opportunities and potential pitfalls with #RTdrugcombo UKIOCongress #UKIO2019 Precision RT crucial, DDRi & IO targetted drugs of interest

#RadBio Fact Did you know? #RadBio provides scientific insights that guide #Clinicaltrial and advance #cancer #patient care.
👉The discovery that #stemcells impact tumour control
👉The identification of druggable molecular signals #RTdrugcombo
#cancer research #RadOnc

What a cool #RedJournal issue! Delighted that phase I results of our PARADIGM study of RT-olaparib in #glioblastoma is in there.
Results of randomised phase II expected early 2025.
#radbio #RTdrugcombo #radonc

📢The long awaited, highly anticipated #RedJournal issue on Combinatorial Therapies is out🔥‼️

So many AMAZING reviews & original articles👏🙏Where to begin❓

#RTdrugcombo
Salma Jabbour et al. redjournal.org/article/S0360-…

RT/IO
Amy Wisdom, MD, PhD et al. sciencedirect.com/science/articl…

PARPi/RT

Looking forward to speaking about our 3D in vitro model of #glioblastoma at this launch of the NC3Rs Oncology Network.
Recently refined for medium throughput evaluation of #RTdrugcombo with clonogenic survival as readout
rb.gy/kr44y1

#3Dtrumps2D

I can't overstate how exciting and important this is! Previous trials raised suspicitons that combining #radiotherapy with PARP inhibitors would exacerbate acute toxicity.
Careful RT planning and dosing improves tolerability in non-small cell lung cancer patients!
#RTdrugcombo

Did u know? In the span of 2 yrs (2018-2019) the FDA approved 30 new molecular entities and 68 supplements for oncology indications?!

0 were in combination with RT.

Last indication w/ RT was in 2006!

Had a lot of fun putting slides together for this one.
#RTdrugcombo #radonc

#ESTRO24 in Gorgeous Glasgow will be unmissable! Last chance to register 3rd April.
#radonc #radbio #RTdrugcombo

⬇️This is a very timely and useful overview about the challenges and opportunities associated with combining biological agents with #radiotherapy . More robust and representative preclinical data are needed for sure to design 'winning' trials!
#RTdrugcombo #radbio

3 really interesting talks at #Ph1MCR on Radiotherapy combinations, RaDCom and the CONCORDE study. I'm excited to become more involved in this area of medical research! #RTdrugcombo

Matthew Deek, Rutgers University, on the future of biomarker-guided, metastasis-directed #RTdrugcombo therapies in oligometastatic #prostatecancer .

Concludes a diverse, educational (and quotable) #radonc session 🙏🙏🙏

#radonc #radbio #PCFAcademy

Pattern of response of soft tissue #sarcoma after neoadjuvant radiotherapy. Great team work Centre Leon Berard & #radonc resident superstar Benoît Allignet
Still so much work to do to individualize treatment. Next steps : transcriptomic 🧬biomarkers of response, #RTdrugcombo . Stay tuned

Happy to share with you our recent #review assessing the role of #Radiotherapy for unresectable soft tissue #sarcoma . Another team work with Benoît Allignet.
Future studies in Centre Leon Berard w/ biomarkers, Modern #RT technique, hypofractionation and #RT drugcombo coming shortly.

Thanks for having me Ester! Enjoyable and highly stimulating day - so rewarding to speak in person and field so many thoughtful questions!
RadNetCRUKGlasgow #radonc #radbio #RTdrugcombo

#RTdrugcombo
Looking forward to working with Dirk on the ESTRO Focus Group on this topic!

Our systematic review with pooled analysis of preclinical data of #RTdrugcombo in #pancsm is online Critical Reviews in Oncology Hematology (CROH). #Radiosensitization depends on the type of DDRi and genomic background of cancer cells.
#radbio
sciencedirect.com/science/articl…