حسام قنش | Husam Qanash(@Alahdal_PhD) 's Twitter Profile Photo

🔴 أهم التحديات التي تواجه النجاح السريري لعمليات الزرع من شخص لشخص آخر (allogenic transplantation)⁉️

- أحد أكبر التحديات هي التفاعل بين الجهاز المناعي للمضيف والخلايا المزروعة الأجنبية، فيتكون الجهاز المناعي البشري من أجهزة المناعة الفطرية والتكيفية، وكلاهما قوي للغاية، حيث…

🔴 أهم التحديات التي تواجه النجاح السريري لعمليات الزرع من شخص لشخص آخر (allogenic transplantation)⁉️

- أحد أكبر التحديات هي التفاعل بين الجهاز المناعي للمضيف والخلايا المزروعة الأجنبية، فيتكون الجهاز المناعي البشري من أجهزة المناعة الفطرية والتكيفية، وكلاهما قوي للغاية، حيث…
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Franck Salameh 🇱🇧🇦🇲🇫🇷🏴(@oldlevantine) 's Twitter Profile Photo

I’m a Lebanese Christians with 6000 years of LEBANESE history and two millennia of Judeo-Christian traditions behind me. I consider Arabs and their descendants to be allogenic settler colonialists who ought to recognize their colonialist past with humility, honesty, and respect.

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Roba(@RAH1418) 's Twitter Profile Photo

هل انا اقدر اتبرع لنفسي دم او غيره واحفظه لوقت الشدة ؟
نعم اقدر
موضوع اليوم شى بسيط ( special type of donation ) لما نقرا عن التبرع نفهم ان الشخص يتبرع لشخص ثاني بس هذا ماهو النوع الوحيد ، شخص يتبرع لشخص ثاني نسميه allogenic Blood donation تمام كذا .

هل انا اقدر اتبرع لنفسي دم او غيره واحفظه لوقت الشدة ؟
 نعم اقدر 
موضوع اليوم شى بسيط ( special type of donation ) لما نقرا عن التبرع نفهم ان الشخص يتبرع لشخص ثاني بس هذا ماهو النوع الوحيد ، شخص يتبرع لشخص ثاني نسميه allogenic Blood donation تمام كذا .
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Pancreas surgery meets 🤝 Transplant surgery when it comes to vascular resections in PDAC

🚨 LAPC involving CHA and PV

💉 Folfirinox x12 radiological / biological response + fit for surgery

🌽 CHA divestment
🧞‍♂️ PV resected + 10 cm graft allogenic cadaveric vein

Pancreas surgery meets 🤝 Transplant surgery when it comes to vascular resections in PDAC 

🚨 LAPC involving CHA and PV

💉 Folfirinox x12 radiological / biological response + fit for surgery 

🌽 CHA divestment 
🧞‍♂️ PV resected + 10 cm graft allogenic cadaveric vein
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DGAFMS-MoD(@dgafms_mod) 's Twitter Profile Photo

The Hematology and Bone Marrow Transplant Unit at successfully performed the maiden allogenic in and joined the league of elite centers performing in the country. The index case was a serving air warrior’s son…

The Hematology and Bone Marrow Transplant Unit at #INHSAsvini #Mumbai successfully performed the maiden allogenic #bonemarrowtransplant in #IndianNavy and joined the league of elite centers  performing #allogenic #BMT in the country. The index case was a serving air warrior’s son…
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Erman Akkus(@Erman_Akkus) 's Twitter Profile Photo

📢Pancreatic cancer clinical trials in
AACR

1⃣ CT022 - Mutant KRAS peptide-based vaccine in patients at high risk of developing pancreatic cancer
✅mKRAS-specific T cell response induced

2⃣ CT134 - Neoadjuvant/adjuvant GM-CSF-secreting allogenic pancreatic tumor cell…

📢Pancreatic cancer clinical trials in #AACR24 
@AACR 

1⃣ CT022 - Mutant KRAS peptide-based vaccine in patients at high risk of developing pancreatic cancer
✅mKRAS-specific T cell response induced

2⃣ CT134 - Neoadjuvant/adjuvant GM-CSF-secreting allogenic pancreatic tumor cell…
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Jasmine Sethi(@JasmineNephro) 's Twitter Profile Photo

🫘👉Kidney injury after Allogenic stem cell transplant

🫘AKI/CKD Common post ASCT

👇Causes

🎯Graft versus host disease

🎯Sinusoidal Obstruction syndrome

🎯Infections/Sepsis/BKV infection

🎯Drug toxicity-CNIs

At Onconep Dept of Nephrology, MMM American Society of Onconephrology

🫘👉Kidney injury after Allogenic stem cell transplant 

🫘AKI/CKD Common post ASCT

👇Causes 

🎯Graft versus host disease

🎯Sinusoidal Obstruction syndrome 

🎯Infections/Sepsis/BKV infection

🎯Drug toxicity-CNIs

At Onconep @MMMNephro @onconephsociety
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RahulDoc(@RahulDoc2) 's Twitter Profile Photo

BMT centre at Bikaner is spearheading the mission of free and affordable BMT.They are well equipped & doing 3 to 4 bmts every months including cryopreserved and allogenic bmts. Other centres in our network are patna, esi Faridabad and Indore. National bmt grid is taking shape

BMT centre at Bikaner is spearheading the mission of free and affordable BMT.They are well equipped & doing 3 to 4 bmts every  months including cryopreserved  and allogenic bmts. Other centres in our network are patna, esi Faridabad and Indore. National bmt grid is taking shape
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Jasbinder (Jessie) Chimni (My Opinions only)(@JessieChimni) 's Twitter Profile Photo

Three companies developing allogenic CD19 CAR-T/NK are targeting auto-immune diseases like SLE: 1) $SANA 2) $CRSP and 3) $IPSC. B-cell depletion seems to be the way to re-set the system. Initial data shows that patients with SLE have durable remission for > 24months. The first…

Three companies developing allogenic CD19 CAR-T/NK  are targeting auto-immune diseases like SLE: 1) $SANA 2) $CRSP and 3) $IPSC. B-cell depletion seems to be the way to re-set the system.  Initial data shows that patients with SLE have durable remission for > 24months. The first…
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Jasbinder (Jessie) Chimni (My Opinions only)(@JessieChimni) 's Twitter Profile Photo

$CRSP is targeting another very large TAM with its allogenic CAR-T treatment targeting Liv-1. Looking forward to its pre-clinical data readout on Nov 4. I assume it will include the new potency edits.

$CRSP is targeting another very large TAM with its  allogenic CAR-T treatment targeting Liv-1. Looking forward to its pre-clinical data readout on Nov 4.  I assume it will include the new potency edits.
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rawRMT(@RMTMARCH14) 's Twitter Profile Photo

ALLOGENIC vs AUTOLOGOUS
allogenic
age: >16 or as allowed by doctor
Hgb: >12.5g/dl
Hct: >38%
Temp: 37.5degcel (99.5degfar)

autologous
age: determined by medical director
Hgb: 11gdl
Hct: 33%
Temp: Determined by medical director

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dr abhijit sarma(@abhijitsarma) 's Twitter Profile Photo

Completed 1year of BMT in gmch. 18 cases were done. 14 autologous and 4 allogenic. Congrats to Jeena Baido and her team. Miles to go!

Completed 1year of BMT in gmch.  18 cases were done. 14 autologous and 4 allogenic. Congrats to Jeena Baido and her team. Miles to go!
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Jasbinder (Jessie) Chimni (My Opinions only)(@JessieChimni) 's Twitter Profile Photo

Hepatocellular carcinoma (HCC) is yet another large TAM identified by $CRSP for its allogenic CAR-T. We should have pre-clinical data for this on Nov 4th. Here is some info from a quick Bard search:

'It is important to note that these numbers are estimates, and the actual number…

Hepatocellular carcinoma (HCC) is yet another large TAM identified by $CRSP for its allogenic CAR-T. We should have pre-clinical data for this on Nov 4th. Here is some info from a quick Bard search:

'It is important to note that these numbers are estimates, and the actual number…
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Raghav Sundar(@sundar__raghav) 's Twitter Profile Photo

Excited about the new allogenic CART study for solid tumours in our institution: National University Cancer Institute, Singapore. Sharing details about the ANGELICA trial at in San Diego with Joan Choo and Anand D Jeyasekharan.

Excited about the new allogenic CART study for solid tumours in our institution: National University Cancer Institute, Singapore. Sharing details about the ANGELICA trial at #AACR24 in San Diego with Joan Choo and @adj_23.
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BowTiedBiotech 🧪🔬🧬(@BowTiedBiotech) 's Twitter Profile Photo

HOW BMS VIEWS CELL THERAPY

Engineering:
Single CAR -> Dual CAR -> Multiplexed Edits (immune silence, logic gates)

Delivery:
Lenti -> AVV -> Non-Viral

Manufacture:
autologous -> fast autologous ->allogenic
a/B T-cells -> g/d Tcells / NK-cells

HOW BMS VIEWS CELL THERAPY

Engineering:  
Single CAR -> Dual CAR -> Multiplexed Edits (immune silence, logic gates)

Delivery:
Lenti -> AVV -> Non-Viral

Manufacture:
autologous -> fast autologous ->allogenic 
a/B T-cells -> g/d Tcells / NK-cells
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Valentin Zuchuat(@stratival) 's Twitter Profile Photo

Days 2 and 3: diving deep into the realm of carbonate ramp deposits, with incredible mud mounds+calciturbidites at Ballybunion, and logging our way through allogenic cycles in the Burren (while surrounded by absolutely insane glaciokarstic features and amazing unconformities!)

Days 2 and 3: diving deep into the realm of carbonate ramp deposits, with incredible mud mounds+calciturbidites at Ballybunion, and logging our way through allogenic cycles in the Burren (while surrounded by absolutely insane glaciokarstic features and amazing unconformities!)
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Aster DM Healthcare(@ASTERHealthcare) 's Twitter Profile Photo

A cross-border invitation to oversee the nation’s first-ever Paediatric Allogenic Transplant.⁣

Dr. Stallin Ramprakash, Consultant - Paediatric Haematology, Oncology & BMT at Aster CMI Hospital, Bengaluru, shares incredible insights into the transplant conducted on a…

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💘𝐉𝐞𝐧𝐢💘 𝐕𝐢𝐉𝐚𝐘(@Jeni__Vijay) 's Twitter Profile Photo

Hi im Gokul

My Brother Praveen suffers from blood cancer (Hodgkin Lymphoma). After undergoing many high doses of chemotherapy he has been operated for Stem cell transpalent in December. Since there wasn't much improvement Doctors opted for allogenic stem cell transplant 1/2

Hi im Gokul

My Brother Praveen suffers from blood cancer (Hodgkin Lymphoma). After undergoing many high doses of chemotherapy he has been operated for Stem cell transpalent in December. Since there wasn't much improvement Doctors opted for allogenic stem cell transplant 1/2
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