อันนี้งานดีมาก Nature ตีพิมพ์งานของ MoTrPAC ศึกษา multiomics ของการออกกำลังกายโดยใช้หนูวิ่งสายพาน 8 สัปดาห์ เทียบกับกลุ่มควบคุม โดยศึกษาในเซลล์จาก 18 อวัยวะดูหมดทั้ง genome, transcriptome, metabolome, proteome และ immunome ถือเป็นชุดข้อมูลที่ต่อยอดศึกษาวิทยาศาสตร์การกีฬาได้มาก 👏

#PedsICU
Important work on gut microbiome in children with sepsis and septic shock from AIIMS.
The Microbiome and Metabolome of the Gut of Children with Sepsis and Septic Shock - Jhuma Sankar, Vaishali Thakral....Rakesh Lodha, Sumit Rathore, 2023 journals.sagepub.com/doi/10.1177/08…

1⃣We defined the metabolome of M-CSF- vs GM-CSF-differentiated human macrophages.

2⃣We discovered adenine to be more abundant in M-CSF macrophages.

3⃣Adenine suppressed inflammation and elicited metabolic quiescence

Mechanism to be uncovered...

➡️sciencedirect.com/science/articl…

Beyond excited for this funded #PhD in my team for a #Nutritionist #RNutr or #Dietitian #RD 🧵

Dietary intake in inflammatory bowel disease and its association with gut microbiome, metabolome and treatment response

#IBD #Crohns #UC

kcl.ac.uk/study-legacy/f…

Please #retweet

The plasma metabolome of long COVID patients two years after infection

❗'To our knowledge, this study is the first describing quantitative metabolic perturbations two years after the initial acute COVID-19 infection using targeted metabolomics' INTERESTING 🤔

➡️'The comparison

Breastfeeding, even partially alongside formula feeding, changes the chemical makeup -- or metabolome -- of an infant's gut in ways that positively influence brain development and may boost test scores years later, suggests new #research .

PhD student from our Food Chemistry and Production Research Group UCC School of Food and Nutritional Sciences Paula Rojas presenting her results from Dept of Agriculture, Food and the Marine funded project #MetaBoBainne examining the Irish Milk Metabolome and its relationship with key functional properties of milk

Thrilled to give James Malone-Lee lecture from across the pond! Thanks Bladder Infection and Immunity Group and IUGA for the invitation. Excited to introduce our work on the urinary metabolome with Pieter Dorrestein, Wolfe Lab and Linda Brubaker

Plasma-Induced Changes in the Metabolome Following Vistula Tart Cherry Consumption mdpi.com/2736686 #mdpinutrients via Nutrients MDPI

Reverse metabolomics is a novel strategy to annotate the human metabolome. Check out this commentary on a recent publication in nature. Follow the link to read more: cjnmcpu.com/en/article/doi…
#ReverseMetabolomics

A Metabolome-Wide Mendelian Randomization Study Identifies Dysregulated Arachidonic Acid Synthesis as a Potential Causal Risk Factor for Bipolar Disorder

'Our findings support the notion that arachidonic acid and other polyunsaturated fatty acids may represent potential targets

Gut microbiome and metabolome profiling in Framingham heart study reveals that humans have cholesterol-metabolizing bacteria.
cell.com/cell/abstract/…

CU Medicine discovers #gutmicrobiome and #metabolome markers can predict long-term #COVIDvaccine effectiveness. Low levels of #Bifidobacteriumadolescentis and its #metabolites in gut led to shorter #immune memory following an #mRNA COVID vaccine💉 bit.ly/3M4CfEI

📖:

Longitudinal multi-omics analysis uncovers the altered landscape of gut microbiota and plasma metabolome in response to high altitude dlvr.it/T599pb

📢Excited to share this paper summarising ideas I have been thinking about for quite some time:

A trait-based framework linking the soil metabolome to plant–soil feedbacks New Phytologist

doi.org/10.1111/nph.19…

Great collaboration with M. Semchenko (@PlantEcoEvoUT) and R. Callaway

Effects of Supplemental Lighting on Flavonoid and Anthocyanin Biosynthesis in Strawberry Flesh Revealed via Metabolome and Transcriptome Co-Analysis mdpi.com/2747066 #mdpiplants via Plants MDPI

I am hiring a computational scientist to join the The Precision Immunology & Microbiome Medicine Laboratory at UPenn!

If you have an interest in #multiOMIC analysis & integration of #microbiome , metabolome & immune profiling data, apply here wd1.myworkdaysite.com/en-US/recruiti…

Please RT 🙏🏿

Revitalizing Vision: #Metabolome #Rejuvenation Can #Slow #Retinal #Degeneration

A CRISPR-based gene therapy can delay progression of RP for about one month in mouse models of the disease, equivalent to about 10 years in humans.... scitechupdates.com/revitalizing-v…