Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage | PNAS pnas.org/doi/abs/10.107…

Microglia as integrators of brain-associated molecular patterns dlvr.it/T5wPW3 #immunology

PAPER ALERT! Human microglia are very temperamental and if you ever tried, you know they don't like to be transfected. But did you know that you can modulate them with ASOs? We show here the selective modulation of human microglia gene expression and function in vivo!

Check out this recently published paper in LSA: Frataxin Deficiency Shifts Metabolism to Promote Reactive Microglia via Glucose Catabolism @lettieribarbato Università di Roma Tor Vergata
hubs.la/Q02tjvw30

So excited to be at the Wings for Life scientific meeting in beautiful Salzburg! 💡🧬🔬
Wings for Life World Run
#spinalcordinjury
#microglia

Microglia as integrators of brain-associated molecular patterns: Trends in Immunology cell.com/trends/immunol…

On this week’s blog: New #NIH -funded research points to a possible immunotherapy for #Alzheimer ’s that would clear brain-damaging amyloid plaques by releasing immune cells called microglia. bit.ly/3w7uYzs

Have you heard of the itaconate shunt hypothesis for #MECFS ?

twitter.com/OpenMedF/statu…

In this study endogenous itaconate itself reduced levels of the neuroinflammatory cytokines IL-1β and IL-6, as well as suppressed activation of microglia and astrocytes in the hippocampus by…

Xenon gas reduces post surigical pain….how does an “inert” gas have such interesting properties?

$tsoi

peerj.com/articles/16855/

Embryonic microglia maintain the brain's cortical fault lines dlvr.it/T5z3Qf #immunology

Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage | PNAS pnas.org/doi/10.1073/pn…

Dr. Daniela Kocher and team from Hopp-Kindertumorzentrum Heidelberg (KiTZ) show that rebound growth of BRAF mutant pediatric #glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of #microglia -recruiting cytokines.

📖 Read their article here: bit.ly/3W5OHKo

Ouch better be on the move, #Microglia represent less than 15% of the total mass of the brain