Oncology for the Inquisitive Mind(@InquisitiveOnc) 's Twitter Profile Photo

Lung cancer treatment options are exploding! Targeted agent use in neoadjuvant and adjuvant sphere is a big focus. Does Alectinib work in adjuvant setting and can osimertinib find a role neoadjuvantly? Truly a fascinating time!

open.spotify.com/episode/3HrJSI…

account_circle
Patrick Forde(@FordePatrick) 's Twitter Profile Photo

Not one, not 2, but 3 lung cancer plenaries at ! Early telemed pall care, the LAURA trial of consolidation osimertinib after CRT for stage 3 EGFR non small cell lung cancer & the ADRIATIC trial of consolidation immunotherapy after CRT for small cell lung cancer!

account_circle
カブドク(@kabumandoctor) 's Twitter Profile Photo

コンパクトパネルはOsimertinibのコンパニオン診断薬ですよ

Osimertinibが使えない検査なんて誰も出しません笑

account_circle
Sergio Cifuentes(@Onco_Cifu88) 's Twitter Profile Photo

🫁 Osimertinib + LT for 🧠mets in EGFRm NSCLC.
🅰️ 121 patients with EGFRm (19del or L858R)
☢️ 45 in Osi+LT vs 76 in Osi alone
✅ OS: Osi+LT group NR vs. Osi alone 31.2 m
🔺 HR for OS: 0.37
🧠 HR for CNS-PFS 0.36

OncoDaily
OncoAlert

👉🏼 doi.org/10.1016/j.lung…

🫁 Osimertinib + LT for 🧠mets  in EGFRm NSCLC.
🅰️ 121 patients with EGFRm (19del or L858R)
☢️ 45 in Osi+LT vs 76 in Osi alone
✅ OS:  Osi+LT group NR vs. Osi alone 31.2 m
🔺 HR for OS: 0.37
🧠 HR for CNS-PFS 0.36

@oncodaily 
@OncoAlert 

👉🏼 doi.org/10.1016/j.lung…
account_circle
Abhishek Puri (मोदी का परिवार)(@gammaemitter) 's Twitter Profile Photo

New cancer clinical trial: High-dose Furmonertinib in the Treatment in Patients With Advanced, Metastatic NSCLC With Progressed After First- or Second-line Treatment With Osimertinib ift.tt/u7sl5yw

account_circle
Cancer Research(@CR_AACR) 's Twitter Profile Photo

New in Translational from the April 15 issue:
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant in Permissive Cellular Contexts, by Bomiao Hu, Dr. Katerina Politi et al.
bit.ly/3WltzzP
Yale Pathology Yale Cancer Center

New in Translational #CancerBiology from the April 15 issue:
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant #LungCancer in Permissive Cellular Contexts, by Bomiao Hu, @politikaterina et al.
bit.ly/3WltzzP
@yalepathology @YaleCancer
account_circle
カブドク(@kabumandoctor) 's Twitter Profile Photo

②EGFR ex20 insはOsimertinibですらほぼ効かず、EGFRの中でも治療に難渋してきた遺伝子変異です。Amivantamabは有効性を示しており、待望の薬剤です(まだ承認されていませんが)。Amivantamabの承認も、オンコマインが診断薬になるのも時間の問題だと思います。

account_circle
Hidehito HORINOUCHI(@HHorinouchi) 's Twitter Profile Photo

🧐Hide and Seek🥇
🔥LAURA
🎯Osimertinib as consolidation after CRT in EGFRm Locally advanced NSCLC
astrazeneca.com/media-centre/p…
🔥ADRIATIC
🎯Durvalumab as consolidation after CRT in LS-SCLC
astrazeneca.com/media-centre/p…
OncoAlert ASCO

account_circle
EGFR Resisters(@EGFRResisters) 's Twitter Profile Photo

Targeting pyruvate dehydrogenase kinase 1 overcomes EGFR C797S mutation-driven osimertinib resistance in non-small cell lung cancer

nature.com/articles/s1227…

account_circle
Oncology Times(@OncologyTimes) 's Twitter Profile Photo

Osimertinib with platinum-based has received for patients with locally advanced or metastatic whose tumors have EGFR exon 19 deletions or exon 21 L858R mutations. ow.ly/rihx50R715M

Osimertinib with platinum-based #chemotherapy has received #FDAapproval for patients with locally advanced or metastatic #NSCLC whose tumors have EGFR exon 19 deletions or exon 21 L858R mutations. ow.ly/rihx50R715M
account_circle
Rɪᴏʏᴇ Aᴜꜱᴋ(@Polarbear900R) 's Twitter Profile Photo

A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations (OSTARA)
clinicaltrials.gov/study/NCT05801…
✅Sponsor:AstraZeneca

account_circle
Abhishek Puri (मोदी का परिवार)(@gammaemitter) 's Twitter Profile Photo

New cancer clinical trial: JMT101 Combined With Osimertinib in Patients With Stage Ⅲb-Ⅳ Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Common Mutations ift.tt/wVL54hn

account_circle
Rɪᴏʏᴇ Aᴜꜱᴋ(@Polarbear900R) 's Twitter Profile Photo

Osimertinib re-administration for CNS metastases in NSCLC positive for EGFR activating mut
bit.ly/44bY2T0
✅No apparent correlation was observed between the interval from the end of the initial Osi to re-administration of Osi and the PFS with regard to CNS lesions.

account_circle
BMC Medicine(@BMCMedicine) 's Twitter Profile Photo

Ruoshuang Han, Haoyue Guo, Jinpeng Shi and colleagues investigate the impact on osimertinib-resistant non-small cell lung cancer of combination therapies.
Read the full study here: bmcmedicine.biomedcentral.com/articles/10.11…

Ruoshuang Han, Haoyue Guo, Jinpeng Shi and colleagues investigate the impact on osimertinib-resistant non-small cell lung cancer of combination therapies.
Read the full study here: bmcmedicine.biomedcentral.com/articles/10.11…
account_circle