bitaceae KochengFess v2 Spill fungsi ubiquitin

🧬Inborn Error of Immunity⚠️
➡️ 'VEXAS' Syndrome
▪️ one of the newest autoinflammatory disorders
🗓️ first identified in 2020
- number of known patients growing rapidly
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sciencedirect.com/science/articl… #bioinformatics #openscience #rstats #itrtg #raredisease #immunology

Yogesh Yogesh Kulathu gave a great talk on branched ubiquitin chains introduced by John Christianson Lab at the Oxford Ubiquitin Club. It seems the p97 system is again the main player in the story 😊.

New research reveals the hidden role of ubiquitin protein in shaping fear memories, potentially driving PTSD in females. This opens up new avenues for gender-specific therapeutic treatments.

#neuroscience

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Keep it comfy wherever you go with EcoFlow's WAVE 2. It runs wirelessly for up to 8 hours and can be charged quickly via AC, solar, cars, or power stations. 🔋

Get simple, secure, and sustainable flash for every budget with NetApp solutions powered by CDW Corporation. #AllFlash #DataStorage #HybridCloud #CloudManagement

Presented by NetApp and CDW. #ad

「積集合」は「共通部分」と「直積集合」の両方を指していて曖昧なので、共通部分のことは共通部分と呼んだほうがいい

circINSIG1
A novel protein encoded by circINSIG1 reprograms cholesterol metabolism by promoting the ubiquitin-

scopus.com/inward/record.…

doi.org/10.1186/s12943…

UbInPD by c-degron pathway lnkd.in/gadxbxdJ

Everything is fine 👌
Get it👉spacespeaker.co/tts0202

Online Now: Ubiquitin-independent proteasomal degradation driven by C-degron pathways dlvr.it/SpB3Jj

Rabbi Mordechai Lightstone Mike Cohen ([email protected]) Chabad.org A being able to add a cubit to the measure of physical being must out of necessity have full paternal DNA everyone else lacks due to emnity between the sperm & egg via ubiquitin. As such, for being the only begotten of the father full of grace & truth, the almighty is FULLY MALE.

Deficiency of Ubiquitin-like modifier activating enzyme 1 as VEXAS Syndrome👇🏽

Research could lead to new #treatment for CRPC?
🧬Castration-resistant prostate cancer (CRPC) remains a clinical challenge - the androgen receptor (AR) is a key player.
🧬E3 ubiquitin ligase #TRAF4 plays crucial role, causing atypical AR ubiquitination 🔬
🧬TRAF4 promotes…

Pivotal Protein in Female PTSD Identified

They found K-63 ubiquitin selectively influences fear memory formation in female brains, potentially contributing to post-traumatic stress disorder (PTSD).

neurosciencenews.com/ptsd-female-pr…

#PTSD

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🔎Our recent findings published in J Cell Science reveal the involvement of two ubiquitin conjugating enzymes- UBE2D1 and UBE2D2 in VEGFR2 proteolysis and turnover, that regulate angiogenesis.
✅Link to full article: journals.biologists.com/jcs/article/do…
#angiogenesis #rtk #ubiquitination

At last! Identification and Classification of Papain-like Cysteine Proteinases jbc.org/article/S0021-…

Team Ubiquitin💪

Hideaki Morishita nature Mizushima Lab (UTokyo) 学校法人 順天堂/JUNTENDO University Congratulations!

Very interesting work that shows that ubiquitin-independent degradation by the proteasome is more prevalent than currently appreciated

An interesting bioinformatical classification of papain-fold proteases with a focus on #DUBs , quite similar to this 2020 DUB-centric analysis: life-science-alliance.org/content/3/9/e2… #ubiquitin

2/6 We identified in our #SickleCellTrait mouse models that red blood cell sickling induces chronic renal medullary hypoxia leading to degradation of #SMARCB1 via the ubiquitin–proteasome system which can be prevented by K62R mutation.

🔉If you miss our paper about #autophagy and ESCRT on endolysosomal repair in #dicty just check out the final version finally online eLife - the journal

elifesciences.org/articles/85727…

Find now all information and supplementary material !

🚨 New release from our group !

If you want to know more about an E3-ligase regulating the crossroads of ESCRT and autophagy pathways just check out our paper out in eLife - the journal 👇👇

elifesciences.org/articles/85727

Female Brain’s PTSD Regulation Mechanism Discovered - Bollyinside bollyinside.com/news/fashion-l…

💍TRAF trimers form #ImmuneSignalling networks via RING domain dimerization

🖊Catherine Day & team University of Otago

➡bit.ly/41KtfcX

#Immunology #TumorImmunology #ubiquitin