What happens to the immune landscape during a malaria infection? Our immune profiling of patients out now in Nature Communications. nature.com/articles/s4146…

Drug resistance allows malaria parasites to evade drug therapy, but what happens when the parasites try to spread? Hayley Buchanan Justin Boddey Robyn McConville biorxiv.org/content/10.110…

#Thailand reports 282% increase in #chikungunya in 2023 to date outbreaknewstoday.com/thailand-repor…

A lot of emotion, nostalgia, fun revisiting Johns Hopkins Malaria Research Institute today. 12 years after I trained here learning P. falciparum transmission. Some lovely familiar faces, many new ones. Thank you all for a stimulating day discussing #malaria #mosquitoes #vaccines #Tcells #antibodies

Thanks Boris for the awesome discussions about lifecycles, parasitism, and the importance of aspartyl proteases #malaria #cryptosporidium Boris Striepen

Big thank you to Prof David Weiner for the invitation to visit
The Wistar Institute today to discuss aspartyl protease inhibitors and #malaria chemovaccination. Impressive infectious disease and cancer vaccine research happening under one roof!

Amazing completion seminar by Robyn McConville !! 🤩🤩 She tackled so many things throughout her PhD, generated amazing phenotypes and together with Justin Boddey might reshape the way we think about #plasmodium protein export.. 🤯🥳 Congrats Robyn 🤗

Holy wow! This new infrared image of Jupiter’s moon Io from the Juno spacecraft shows volcanoes, lava flows and lava lakes glowing with heat radiation!

50 years ago #OTD . One of my absolute favourite photos from the Apollo programme.
2 miles away, the Lunar Module, Challenger - Cernan and Schmitt's home for 3 days, sits quietly on the Taurus-Littrow valley floor, dwarfed by the spectacular lunar landscape.

#ApolloRemastered

Discovery of WM382, a potent plasmepsin IX and X dual inhibitor with robust in vivo efficacy at multiple lifecycle stages of the malaria parasite and an excellent resistance profile.

The #photography on Apollo 17 was insanely good.
This shot, of some of our last steps on the Moon, was taken 50 years ago today.
Digitally remastered here, you could almost reach out and pick up a rock.
#OTD #ApolloRemastered

Flight day 9: Orion catches a better image of Earth

The Space Launch System has roared to life, launching the Orion Spacecraft spacecraft on its journey for #Artemis I! Look out Moon, we are on the way!

Greetings Twitter world! 👋 We are the newly formed Australian Glycoscience Society (colloquially known as Glyco@Oz). Get to know more about us in the upcoming 2022 AGS & Warren Workshop or visit ozglyco.org
Please help us spread the word, #RT is appreciated!

Very cool finding, Man-C-Trp, a quirky form of protein C-glycosylation with poorly understood function, has an important role in P. falciparum transmission. nature.com/articles/s4146…

Necroptosis, a form of inflammatory cell death, has no role in causing liver pathology during infection and steatohepatitis Gastroenterology Simon Preston
#NASH #steatohepatitis #malaria
gastrojournal.org/article/S0016-…

Lots of talk about egress, movement and pathogen host interaction. Some interesting reads, and a commentary of Johannes Dessens and myself! If you want to learn about parasite movement, have a read 😇😊

Time check: 12 hours to launch #Artemis to the Moon!

Tryptophan C-mannosylation in malaria parasites 🥳 #glycotime
#malaria
Dr. Alan John Niall Geoghegan Nichollas Scott Cindy Evelyn
Dr Kelly Rogers OAM @Otis_Coburg
Ethan Goddard-Borger Eva Hesping Sabrina Caiazzo_Research officer
WEHI (Walter and Eliza Hall Institute) Nature Communications
rdcu.be/cSCpU

Interesting! Tryptophan C-mannosylation of #Plasmodium falciparum proteins bearing TSR repeat domain is critical for transmission. When absent, destabilization of TRAP adhesins, defective ookinetes, no mosquito infection. Ethan Goddard-Borger Justin Boddey
go.nature.com/3vrNS0s
#glycotime