Congrats #CancerGrandChallenges team Mutographs on their paper in nature today!

Showing the power of their mutational epidemiology approach, they uncovered mutational signatures underlying global variance in #KidneyCancer incidence rates.

Read: nature.com/articles/s4158… (1/5)

Join us at the 2024 ASCO Annual Meeting next month! We look forward to sharing details from our ongoing #clinicaltrial investigating VLS-1488, our internally discovered #KIF18A inhibitor, for the treatment of advanced #cancers .
#ASCO24

What happens when you use >1 million echo video clips with expert interpretation to train an #AI ?
nature.com/articles/s4159…
Nice advance by David Ouyang, MD and colleagues Cedars-Sinai Cedars-SinaiMed Nature Medicine

#CornellTech welcomed Governor Kathy Hochul to campus today to celebrate the creation of the historic #EmpireAI consortium. Participants included Dean Greg Morrisett & VP for Research and Innovation at Cornell University Krystyn Van Vliet, and other tech leaders. #CornellAI

You should read the @PCAST report on supercharging research with #GenAI Credit goes to Terrance Tao, Laura Green & Team.
whitehouse.gov/wp-content/upl…

Now online in Cancer Discovery: back-to-back papers from the labs of Sheila Stewart and David DeNardo WUSM on immunosuppression by senescent CAFs in breast and pancreatic cancers doi.org/10.1158/2159-8… doi.org/10.1158/2159-8… Jennifer Jiayu Ye Jad Belle #DevashishSen Washington U. Med Siteman Cancer Center

We hope to see you Monday! WCM Englander Institute for Precision Medicine
#PrecisionMedicine Pashtoon Kasi MD, MS Cora Sternberg

Last nature paper from Cavalli's team InstituteHumGenetics
👁️ rdcu.be/dFD2s
'Transient loss of Polycomb components induces an epigenetic cancer fate'
The birth of an epigenetic cancer (left, control tissue, right, epigenetic cancer with proliferating cells labelled in red). 👇

Our most complex biologic system—immunity—is reviewed in 3 new Cell papers, open-access
Adaptive
cell.com/cell/fulltext/…
Innate
cell.com/cell/fulltext/…
New insights
cell.com/cell/fulltext/… Ruslan Medzhitov

🎉 Announcing the recipient of the #TCT2024 Career Achievement Award: Dr. Robert Harrington! 🏆

🌟 Congratulations are in order for his remarkable impact on interventional cardiology, pioneering advancements in patient care, research excellence, and invaluable mentorship. 🙌

Just published
Our review article of all the medical #AI randomized controlled trials The Lancet Digital Health
thelancet.com/journals/landi… Ryan Han Julián Nicolás Acosta Pranav Rajpurkar

Based on numerous requests we are providing the open access ShareIT link for our Nature Medicine article on identifying and mitigating disparities in pathology AI models.

Open read link: rdcu.be/dFdMS
Journal link: nature.com/articles/s4159…

mtDNA heteroplasmy dynamics are so complex, even paradoxical. To understand why, we combined precise mtDNA editing w/a new method SCI-LITE. In dividing cells, selection (not drift) acts on cell (not intracellular) fitness to shape population heteroplasmy. rdcu.be/dFDCY

🔥Last paper of the lab with amazing collaborations with colleagues InstituteHumGenetics IDIBAPS Inst. Carnot CALYM :

Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation ashpublications-org.insb.bib.cnrs.fr/blood/article/…

InstituteHumGenetics Université de Montpellier CHU de Montpellier Institut universitaire de France (IUF)

Excited to share our new paper in Cell on spatial organization in glioblastoma authors.elsevier.com/c/1izT9L7PXqQI9. We combine spatial transcriptomics (Visium) and proteomics (CODEX) to reveal five-layer organization of cellular states and a role of hypoxia as tissue organizer. 1/

NCI researchers have developed an #AI tool that has potential to one day help doctors more precisely match cancer patients with drugs that will be most effective for their cancer. #PressRelease NCI Center for Cancer Research Eytan Ruppin, MD, PhD spr.ly/6010bjLDE

AI for public good: Empire AI, a $400M effort to create a shared academic research computing facility in New York, is set to advance dozens of ambitious, cross-disciplinary projects at Cornell University. Governor Kathy Hochul Cornell Tech Cornell UniversityCIS Weill Cornell Medicine news.cornell.edu/stories/2024/0…

Shape-shifting proteins: Researchers at Weill Cornell Medicine have developed a powerful technique to generate “movies” of changing protein structures, at speeds of up to 50 frames per second. NatureStructMolBiol Scheuring Lab NIH news.cornell.edu/stories/2024/0…

Nightingale Health to establish a laboratory in the United States with Weill Cornell Medicine as the first customer:

nightingalehealth.com/news/nightinga…

As a member of the WCM Englander Institute for Precision Medicine my team at WeillCornellQatar will be involved in this collaboration with Olivier Elemento and Jan Krumsiek.

Take a look at how the number of federal regulations and policies governing research at universities has dramatically increased over the years.

This adding an enormous cost of doing research.

(Source COGR)