Misleading to claim #donanemab or any amyloid lowering Rx will allow an #Alzheimer ’s patient to continue to drive independently. Inserting the claim immediately outside a respected KOL’s quote also risks wrongly attributing this to them. Not a good look Robert Howard Ash Paul

cricket.one/cricket-news/p…
What could possibly go wrong when a supposedly bankrupt cricket star is bailed out by the richest family in the country to abruptly switch sides in the most lucrative T20 league in the world? 🤷‍♂️

We're on! April 19 - register now! mcisymposium.org/program

Is amyloid=Alzheimers? YES: Alzheimer's Association
Does lowering brain amyloid predict benefit? YES: U.S. FDA
Is lowering brain amyloid safe & effective? YES: drug makers
Should we cover amyloid abs? YES: CMS
Should we prescribe them? YES: MDs #Consensus #no -debate Alberto J Espay

Only 1 in 4 respondents to a recent McKnight Brain survey have talked to their doctor about brain health. Talking to your doctor is a great way to be proactive about maintaining your brain health. Learn more & get tips to start the conversation here: McKnightBrain.org/BrainWorks.

Fewer Than 1/2 of Accelerated Approval Rx Showed Clinical Benefit in Confirmatory Trials After 5 Years tinyurl.com/ydfznwx3
Dave Weisman Oliver Barnes Ash Paul Robert Howard A sobering and timely analysis suggesting that cancer-envy in dementia drug approvals may be misplaced

It’s a grim business when even getting your manuscript past the editor’s desk and into reviewer’s hands seems like a major victory 🤷‍♂️

A breathtaking story indeed. James Temperton 🙏 thanks for writing it. Inspiring, sobering, uplifting and sad in equal measure. Jason Mast did you see this?

#DYK simple lifestyle changes can help maintain brain health with age? Only 32% of McKnight Brain survey respondents believe there are steps they can take to protect their brain health, but eating a healthy diet, exercising & getting enough sleep can benefit the brain & body.

We're excited to be kicking off Cognitive Aging Summit IV in partnership with Foundation for the National Institutes of Health & The National Institute on Aging (NIA). Scientific presentations on the social, biologic & genetic factors that drive healthy aging are underway. If you aren't here, join us virtually at: fnih.org/our-programs/c….

The fourth Cognitive Aging Summit is underway!

It’s not too late to join us via livestream to learn about the individual factors that affect brain health as we age: lnkd.in/eJbBhZhV

McKnight Brain The National Institute on Aging (NIA)

#CASIV #aging #healthyaging #fnih

Use of Lecanemab for Patients With Cardiovascular Disease jamanetwork.com/journals/jama/…

A friendly, respectful & collegial debate on the pros & cons of amyloid-targeting antibodies at the #ASENT meeting in Bethesda ASENT.org with Dave Weisman Alberto J Espay & John Dickson from MGH. Thanks for participating!

This situation is surreal. WTF @harvard and CDC?

“Science cannot survive in a society that does not value truth and strive to discover it. The scientific community will gradually lose public support and slowly disintegrate in such a culture.”

Safe to say this is the most head spinning, vertigo-inducing day for neurodegenerative diseases that I can recall Robert Howard Ash Paul Alberto J Espay Matthew Schrag Tharick Pascoal

Effects of unblinding may explain a significant share of the observed treatment effects for all amyloid-targeting Rx Sarah Ackley, PhD Robert Howard Kathy Liu Lon S. Schneider, MD Maria Glymour Nicolas Villain Matthew Schrag