I'm thrilled - ETH Zurich is supporting our ongoing 3R research efforts! 🙏💪

Headed by Oliver Sturman , the new 3R Hub will help implement technological advancements in animal behavior assessment across labs. In line with our Swiss 3R Competence Centre (3RCC) funded work - more details will follow!

and because when we start we don’t stop - here is another Gapplab paper hot from the Nat.communications press nature.com/articles/s4146…
Presenting “stress extinguisher” ETH Zurich @MGazorpak Miriam Kretschmer Selina Frei Iryna Ivanova Mattia Privitera

Interested in #5fC , #Tdg , #chromatin , #stress , #intergenerationaleffects and #sperm -
check out the first Gapplab research paper TranslationalPsychiatry Miriam Kretschmer
Hot from the press: thread below—link.springer.com/10.1038/s41398…

How can stress affect our children?
Could chromatin accessibility convey intergenerational information? Excited to share our new publication with my co-first-author Vincent Fischer! nature.com/articles/s4139… Katharina Gapp TranslationalPsychiatry

Mums should rest and de-stress before and during pregnancy - but what about Dads?
In our new review, we look at how stress changes epimodifications in sperm and how this impacts the embryo´s health mdpi.com/2218-273X/13/1… Biomolecules MDPI

Interested in single-nucleus RNAseq in snap-frozen brain tissue?

Rebecca Waag has perfected the method in our lab and has written a detailed protocol. With tips and tricks for experimental design and data analysis - go check it out (open access)! …rentprotocols.onlinelibrary.wiley.com/doi/10.1002/cp…

GAPPENE lab welcomed some new members with lots of fun team building during our mini-retreat! Miriam Kretschmer Julia Bode

For a deep dive into GR mediated inheritance, with a look into sperm and embryogenesis, find me at poster #1! Looking forward to exchange and discuss with you!
#eisz23

First day of the Epigenetic Inheritance Symposium in Zürich. Looking forward to exciting talks and discussions!
#EISZ2023

I cannot put in words how proud I am to have had the opportunity to work together with @MGazorpak during her PhD sprint in the GappLab and Johannes Bohacek!
Really great work, and more importantly an amazing colleague!

Closing off the absolutely amazing #EMBLchromatin conference in style on the rooftop of the double helix building! Looking forward to the next one!

We had a marvelous time with you yesterday at the #EMBLChromatin pub quiz! Lots of creative heads in the crowd, look at these amazing drawings ✏️👏🏻

Day 2 of the #emblchromatin conference. After a great round of talks on developmental epigenetics, come and find me at poster nr. 145 for a deeper dive into the role of glucocorticoid receptors in gametes and early embryonal development!

Excited to be joining the #EMBLchromatin conference in the beautiful city of Heidelberg today! Looking forward to a fascinating week full of science and networking!

And for the #stressrelief enthusiasts - another meeting must for 2025- in scenic alpine surrounding (featuring my dear hometown in Austria)! Help spread the word!

Come join us in beautiful Grenoble this autumn!

Interested in stress hormone signalling? Look no further - in our new preprint we harness PROTAC technology to interfere with GR proteins. Great work by @MGazorpak and Karina Hugentobler and all co-authors!

🚨PREPRINT ALERT🚨 Our latest work provides a multiomic dissection of the molecular changes triggered by acute #stress . It comes with an interactive app that will make stress researchers jump with joy! Thread and a wild trailer by @Osturmscience below 🔊👇biorxiv.org/content/10.110…

The new preprint of the collaborative work of Eric Miska Lab, Guillermo Parada, Martin Hemberg and Johannes Bohacek shows that a single dexamethasone gavage acutely alters sperm RNA!