Study finds elevated NT-proBNP levels in T2 #Diabetes patients indicate worse #HeartFailure and kidney outcomes, regardless of prior HF history. Higher risk with HF diagnosis. #CardiovascularRisk #CANVAStrial
Baim faculty James Januzzi Jr MD Javed Butler
doi.org/10.1016/j.card…

Grateful for another day of meeting friends and mentors, old and new. Thanks all for stopping by!
American College of Cardiology #ACC2024
Joseph Marine Shahzeb Khan Mona Mahmoud UToledo Medicine

New #ACC24 #SimPub in Journal of Cardiac Failure led by ⭐️Duke IM Residency Hubert B Haywood

What proportion of patients hospitalized for #HF are potentially eligible for a #HospitalAtHome strategy?

Javed Butler Gregg Fonarow MD Duke Clinical Research Institute Duke IM Chief Residents Duke Cardiology Fellows

onlinejcf.com/article/S1071-…

Inspiring presentation from Andrew J Sauer MD reporting results from AHA Science #IMPLEMENT_HF targeting #GDMTworks for #HF

Change is possible

#QuadTherapy is possible

In-hospital initiation is possible

Gregg Fonarow MD Clyde Yancy, MD, MSc Javed Butler
Duke Clinical Research Institute AHA Research #GWTG_HF #ACC24

Absolute pleasure to host Tor Biering-Sørensen, MD, MSc, MPH, PhD at Duke Heart Duke Clinical Research Institute! An amazing body of work and he is just getting started.

Next ➡️ ACC

Adrian “WE NEED RCTS!” Hernandez Robert Mentz, MD Mark Kittipibul MD Husam Salah Steve Greene Shahzeb Khan Manesh Patel

New data from #TRANSFORM_HF now in European Society of Cardiology Journals #EJHF

Across the spectrum of patient kidney function, no significant difference in clinical or patient-reported outcomes between torsemide and furosemide for treatment of HF.

Duke Clinical Research Institute Yale Cardiology

onlinelibrary.wiley.com/doi/full/10.10…

Role of telemedicine in the management of obesity: State‐of‐the‐art review - Obesity Reviews

onlinelibrary.wiley.com/doi/10.1111/ob…

Kainat Shariq Javed Butler Harriette Van Spall, MD MPH Shahzeb Khan Steve Greene ambarish Adam DeVore, MD, MHS Tariq Jamal Siddiqi

CCCEnthusiasts Elliott Miller Garima Dahiya, MD Carlos L. Alviar MD, FACC Ran Lee, MD, FACC Andrew Higgins Jessica Fleitman MD Ricky Hansra, MD 🫀 Shashank Sinha, MD, MSc, FACC, FAHA And here we go….. Duke Cardiology Fellows BalimSenman Manesh Patel

🚨New in JACC Journals w #ACC24

🇺🇸 analysis of newly diagnosed #HFrEF

>4 in 5 pts eligible for quad GDMT

Yet, <1 in 6 prescribed it.

Potentially completely generic triple GDMT (RASi + BB + MRA)??.....only ~4 in 10 eligible pts even prescribed this.

jacc.org/doi/10.1016/j.…

Nationwide US cohort 🏨 for newly diagnosed HFrEF n=33,036

>4 of 5 patients eligible for quadruple GDMT (>9 of 10 triple GDMT)

<than 1 in 6 were prescribed it

Substantial survival benefits being missed

doi.org/10.1016/j.jchf…

JACC Journals Steve Greene Duke Clinical Research Institute AHA Science

Thank you very much for highlighting our work Shahzeb Khan , and congratulations on the amazing accompanying editorial! A must read for treatment of heart failure patients!
Article: jacc.org/doi/10.1016/j.…
Editorial: jacc.org/doi/10.1016/j.…

1⃣ effectiveness endpoint: 6-month incidence of HF hospitalization or all-cause mortality compared to a performance goal
➡️Good GDMT and otherwise comparable to prior remote monitoring trials (GUIDE, MONITOR, CHAMPION)
➡️High implant success
➡️Low event rate post implant

📌 Our editorial in JACC Journals regarding serial NT-proBNP measurements and implementation of GDMT.

📌 Potential use of NT-proBNP as a virtual physical exam

jacc.org/doi/10.1016/j.…

Comment to the excellent 📝 by Michael Fuery MD, Tariq Ahmad MD MPH et al: jacc.org/doi/10.1016/j.…

Our research letter in #EJHF highlighting the significance of WATCH-DM score in identifying subclinical cardiomyopathy among individuals with DM!

A special thank you to ambarish for the great mentorship!

onlinelibrary.wiley.com/doi/10.1002/ej…

⁦BalimSenman⁩ & ⁦CCCEnthusiasts⁩ discussing opportunities for international partnerships ⁦European Society of Cardiology⁩ #ACVC2024 - training, research, mentorship, education & cultivating a community ⁦ACVCPresident⁩ ⁦EHJACVC Editor-in-Chief⁩ ⁦Manesh Patel⁩

BAN-ADHF score (BUN, creatinine, NP levels, atrial fibrillation, BP, HTN, diuretic, and HFH) - simple & contemporary score for ADHF patients (using ROSE, DOSE, CARRESS-HF, ATHENA-HF, ESCAPE, GWTG) JACC Journals #JACCHF Matt Segar Shahzeb Khan Kershaw Patel Javed Butler

Honored to receive the award for the fellows' abstract competition at #THT2024

Thanks to the panel list for the great discussions Ryan J Tedford MD
Manreet Kanwar Andrew J Sauer MD Anu Lala-Trindade

couldnt do this without support from my 🌟 mentor Marat Fudim, MD MHS and the team Dmitry Yaranov!

Heart Failure Post-MI

• HF leading AMI complication (14-36% incidence)
• Complex factors: macro/microvascular issues, inflammation, etc
• 🫀shock extreme, high mortality ➡️early revascularization crucial for survival
• 🗝️Aggressive risk modification, GDMT: ⬆️outcomes

Fostering the Next Generation of Physician-Scientists in Developing Countries: acc.org/Membership/Sec…
So proud of you my friend Shahzeb Khan

🚨The spectrum of post-myocardial infarction care: From acute ischemia to heart failure

❓Incidence and pathogenesis of HF post-MI
❓Current strategies to prevent and treat onset of HF post-MI
➡️Promising therapeutic strategies, and knowledge gaps

sciencedirect.com/science/articl…