Preprint 🚨 This one is important for invasive #Parkinson #neurotech of the future. Deep brain stimulation suppresses oscillatory hyperdirect pathway communication. So does dopamine! Check our #Parkinson study spearheaded by Einstein Center for Neurosciences Berlin #PhD Thomas S. Binns 🧵
biorxiv.org/content/10.110…

Granger causality and time-delay analyses revealed that dopamine and DBS decrease monosynaptic input to the STN. This has important implications for motor control and beyond, e.g. global inhibition as studied by Adam Aron and Jan Wessel, janw.bsky.social.

Hoooo boy do WE have big news from the Cognitive Control Collaborative here at Psychology at The University of Iowa: We're growing to five (5!) labs. And it just so happens to be another California fugitive.

We keep building out here. You keep watching.

Get them started early, folks.

Looking forward to reading this paper, mainly to see which beautiful mind came up with the opinion that LFPs are epiphenomenal or 'the exhaust fumes of more relevant processes.'.
I'm guessing one without ephaptic coupling.

Research assistant opportunity (6 months): Come and work with us on a TMS ⚡️ project looking at causal and temporal role of prefrontal areas in selective attention. More details: jobs.cam.ac.uk/job/45975/ DM Jade Jackson to chat.

Periodic reminder that as usual, I had the correct opinion on the person of the day ages ago and you should just defer to me on everything.

Love to eat healthy

By wirelessly recording signals from deep-brain stimulators in patients with Parkinson's disease in an outpatient setting, Soh et al. show that the STN – known for its role in motor control – also exerts control over non-motoric, attentional processes. tinyurl.com/mvuwy785

Great review of mounting evidence for the role of beta-band oscillations in inhibitory control.

Neural mechanisms of domain-general inhibitory control
cell.com/trends/cogniti…
#neuroscience

Since everybody is posting R01 percentiles, here are mine over time:
2018: 1 (funded)
2020: 9 (funded)
2023: 16 (renewal, not funded)
2023: 19 (renewal, not funded)
2024: 30 (new, not funded)
A career in decline.
Or joining study section in '22 was a mistake. Jury's debating.

Started giving this a cursory read, then read the whole thing.
Ho-ly shit! Need to go back in detail, but this type of work makes you think that what we're doing as neuroscientists may actually be worthwhile.
(Though this particular study is beyond my own level of sophistication)

New paper out in Movement Disorders Journal on subcortico-cortical connectivity! We compared neuronal oscillations in 2 DBS targets, STN and VIM, and found that they differ wrt their synchronization with cortex. Awesome work by fabulous first author Alexandra Steina 🚀 doi.org/10.1002/mds.29…

In our work that was recently accepted in Brain , we have shown that the subthalamic nucleus is causally involved with attentional suppression. More summary in Jan Wessel, janw.bsky.social 's post.
I appreciate Jan for giving me an opportunity to lead this cool project.