Sabine D. Brookman-May(@brookmans76) 's Twitter Profileg
Sabine D. Brookman-May

@brookmans76

Professor of Urology @LMU_Muenchen, Vice President R&D Bladder Cancer, @JNJInnovMed, GU Oncology, Sports Medicine 🚵‍♀️Passionate Cyclist

ID:1206131683

calendar_today21-02-2013 22:06:03

1,0K Tweets

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2,2K Following

Sabine D. Brookman-May(@brookmans76) 's Twitter Profile Photo

Important work on micro-environment and for potential personalized treatment
👉first single-cell transcriptomic atlas
➡️TP53 and HPV status stratification indicates CSM differences
👉 authors.elsevier.com/a/1i%7Elg14kpl… Maarten Albersen Oscar Brouwer Laura Elst European Urology

Important work on #PenileCancer micro-environment and for potential personalized treatment 👉first single-cell transcriptomic atlas ➡️TP53 and HPV status stratification indicates CSM differences 👉 authors.elsevier.com/a/1i%7Elg14kpl… @MaartenAlbersen @Brouwer_MD_PhD @ElstLaura @EUplatinum
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Sabine D. Brookman-May(@brookmans76) 's Twitter Profile Photo

Well done Markus Eckstein Niklas Klümper
👉NECTIN4 amplification could possibly be a predictive biomarker for EV treatment response in mUC
👉One limitation is the retrospective analysis of samples
➡️Call for continuous biomarker assessment in clinical studies

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Sabine D. Brookman-May(@brookmans76) 's Twitter Profile Photo

Excellent mini-review
of response to Anti- EV in
➡️More research needed to identify biomarkers predictive of response to EV treatment (and others) and to identify patients not benefiting from treatment
sciencedirect.com/science/articl… Eur Urol Focus

Excellent mini-review #biomarkers of response to Anti-#NECTIN4 #ADC EV in #BladderCancer ➡️More research needed to identify biomarkers predictive of response to EV treatment (and others) and to identify patients not benefiting from treatment sciencedirect.com/science/articl… @EurUrolFocus
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Sabine D. Brookman-May(@brookmans76) 's Twitter Profile Photo

Sharing our study on disease trajectory among men with HR localized treated with RP or RT from the PC database Sweden
▶️10% of men overall died from PC in 10 years post diagnosis
▶️1/3 of men who received secondary ADT died from PC 10 years after ADT
BJU International

Sharing our study on disease trajectory among men with HR localized #ProstateCancer treated with RP or RT from the PC database Sweden ▶️10% of men overall died from PC in 10 years post diagnosis ▶️1/3 of men who received secondary ADT died from PC 10 years after ADT @BJUIjournal
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Sabine D. Brookman-May(@brookmans76) 's Twitter Profile Photo

Congratulations again to study Gaëtan Devos steven joniau Alexander Giesen
▶️MRD doesn't predict BCR
▶️We will need to wait for a possible significant impact on MFS with longer FU
▶️ypT stage correlates with outcomes
👉 Did downstaging after neoadjuvant treatment correlate with BCR?

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Sabine D. Brookman-May(@brookmans76) 's Twitter Profile Photo

Learning from the Dutch example
👉 Management might be improved by centralized , which also resulted in intensified and collaborations
👉 Potential learnings not only for penile but also other rare/orphan cancers
BJU International Oscar Brouwer

Learning from the Dutch example 👉 #PenileCancer Management might be improved by centralized #treatment, which also resulted in intensified #research and collaborations 👉 Potential learnings not only for penile but also other rare/orphan cancers @BJUIjournal @Brouwer_MD_PhD
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Sabine D. Brookman-May(@brookmans76) 's Twitter Profile Photo

The response to this question is very easy
The especially over the past two years has impacted quality and quantity negatively, which impacts the price
We will need to get used to it

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