Charlie ChangWon Lee
@charliecwlee
MD/MBA Candidate @HarvardMed @HarvardHBS
ID:2823341573
11-10-2014 18:50:34
62 Tweets
187 Followers
615 Following
Re-sharing our recent review on single cell eQTLs - it’s now available open access! Annual Reviews 🧬
Scientists in the Baker Lab have designed new proteins that change shape upon binding a target molecule. This research opens the door to new applications in drug delivery, environmental sensing & more.
Florian Praetorius, Phil Leung
bakerlab.org/2023/08/17/swi…
Do 💵financial penalties 💵improve compliance with the CMS hospital price transparency regulations? In our new JAMA Network JAMA NetworkOpen paper, Yunan Ji and I find that yes, penalty increases were associated with compliance increases from 2021-22 jamanetwork.com/journals/jaman… a 🧵
New cross-sectional study finds that more than half of #AcceleratedApproval confirmatory trials are completed after the deadline set by the FDA. Aaron Kesselheim Ben Rome Program On Regulation, Therapeutics, And Law ja.ma/3KndEuB
Excited to see the project come to life and share our work on in my first, first-author paper! Couldn’t have done it without your mentorship Megan Murray ☺️
Introduction of a citrate-free version of adalimumab in 2018 avoided Medicaid's inflationary rebates and led to >$4B excess spending from 2018-2021. ja.ma/3Jn1d1B Charlie ChangWon Lee Aaron Kesselheim Ben Rome Program On Regulation, Therapeutics, And Law
Example of the economic costs of circumventing Medicaid's Drug Rebate Program inflationary rebates by modifying an older drug.
Led to $4.4B in excess Medicaid spending through 2021 from adalimumab alone! jamanetwork.com/journals/jamai… JAMA Internal Medicine
We keep ignoring somatic mutations in the blood (CHIP) as an important risk factor for atherosclerotic cardiovascular disease, cancer, and all-cause mortality. Now a mechanistic underpinning: TP53, damage repair genes, unraveled Nature Cardiovascular Research
nature.com/articles/s4416…
Homicide is the leading cause of death for Black males age 1-44. It makes me sick.
What if I told you going from A to B reduces nearby gun violence in Black neighborhoods? Well, it does and we showed it in an RCT.
Out today in JAMA Internal Medicine. Short 🧵.
It’s getting a little silly now Erling Haaland. Making goal scoring appear absurdly easy.
1/. In today's Science Magazine, we report bioadhesive ultrasound (BAUS) for long-term continuous imaging of diverse organs --- An ultrasound sticker capable of continuous, on-the-go, high-quality imaging of most parts of the human body.
science.org/doi/10.1126/sc…