Had this honor to share my first co-lead paper on ACS Chem Biol! We designed a new spatiotemporal activation strategy on OGA for controllable O-GlcNAc regulation in cells. Great thanks for supports from christina woo and other coauthors! pubs.acs.org/doi/10.1021/ac…

Check out our joint paper with Christina Woo's christina woo Laboratory! Congrats and big thanks to the heroic efforts from Sun Mi Park and David Miyamoto David Miyamoto et al! We find a potent molecular glue for IKZF2 and CK1alpha that kills leukemia cells. sciencedirect.com/science/articl…

It's finally here! We developed a molecular glue that degrades IKZF2 and CK1 alpha and kills leukemia cells. christina woo and I had an awesome time collaborating with Sun Mi Park and Michael Kharas MSK!

authors.elsevier.com/c/1gjK-5TA51da…

Congratulations to team Saki Hope Flaxman @Big_Fish_Linda nandini v Hannah Dacheng and collaborators Matt Pratt and Binyou! This was a true collaborative effort in the group to discover a degron for cereblon! rdcu.be/cXTkl

Congratulations to all & thanks Amgen for supporting our research!

Harvard CCB open houses back in style with jalapenos

Congratulations Alex and our collaborators at Jnana, this work was key to better understanding the chemistry behind our binding site measurements from cells.

I'm dusting off my twitter account to congratulate Yun_Ge !!! She developed nanobody-splitOGA for targeted protein deglycosylation, fantastic work :) !!!

Turning a glycoside hydrolase into a phosphorylase #glycotime Carme Rovira

pubs.acs.org/doi/abs/10.102…

Discovery of a Small Molecule-Dependent Photolytic Peptide | Journal of the American Chemical Society. A very unusual UV and small molecule induced protein cleavage reaction. pubs.acs.org/doi/pdf/10.102…

A new study of our group is now finished and on ChemRxiv doi.org/10.26434/chemr…. Light-activatable, 2,5-disubstituted tetrazole probes allow residue-specifically studying aspartates and glutamates proteome-wide with high selectivity using chemoproteomics with our isoDTB tags.

Congratulations also to David Miyamoto and Hope Flaxman on their recent publication in Laura Kiessling - discovery of a PTGES binding site using chemical proteomics.

pubs.acs.org/doi/full/10.10…

Our latest preprint and one of my favorites. Great work from @dramirez201292 and Chanat Jay Aonbangkhen ! We used a nanobody fused to OGT to generate a protein-selective O-GlcNAc 'writer'. We're looking forward to feedback from the community.

biorxiv.org/cgi/content/sh…

A huge honor to be part of this group and amazing ceremony! Thank you Carl for hosting my visit!

Wow so exciting !!!

Thank bryan dickinson again for your very kind recognition.

My group has a postdoc position available thanks to this grant and candidates with backgrounds of molecular biology, mammalian cell culture, and directed evolution are highly encouraged to apply!

Our seminar series starts again next Tuesday with Matt Shoulders MIT Chemistry. See you there!

Thanks a lot Matt Pratt and Jiaoyang Jiang for organizing a wonderful GlcNAc symposium at #ACSSanDiego #glycotime . Chemistry ChemistryOpen Editor Francesca Novara was there to witness the brilliant talks by christina woo and Michael Boyce sponsored by ChemBioChem #ChemBioTalents .

Thank you for sponsoring this symposium! We hope to publish in Angewandte Chemie again soon :)

Adding an O-GlcNAc or 'O-GlcNAc Engineering' can improve the serum stability and in vivo efficacy of therapeutic peptides. Our latest paper out in JACS with Seva Katritch, Tom Gardella, Denise Wootten, Patrick Sexton, and Patsy McDonald. pubs.acs.org/doi/10.1021/ja…