The third MASH presentation in the MASLD/MASH section at Liver Connect was 'Role of Non-hepatologists in the Management of Patients with NASH/MASLD' by Dr. Ken Cusi, Endocrinologist.

The number of patients with Type-2 Diabetes and MASH is 'quite staggering'.

ADA 2024…

MASH clinical trials and drugs pipeline: An impending Tsunami . Update Review on MASH Drugs #livertwitter #gitwitter ⁦Naim Alkhouri⁩ pubmed.ncbi.nlm.nih.gov/38502810/?utm_…

🚨 Bariatric surgery types & nutrient supplementation guidelines

🙏 Excellent graphic from @dietitiansondemand

#NutritionMatters #Obesity #BariatricSurgery #MedTwitter #Dietitian

New from us: Liver stiffness predicts progression to liver-related events in patients with chronic liver disease – A cohort study of 14 414 patients
Now in Liver International. Thanks to 1st author dr Hannes Hegmar for leading this!
onlinelibrary.wiley.com/doi/10.1111/li…
#livertwitter

Gut hormones in the pipeline for obesity treatments.
nature.com/articles/s4136…

Really looking forward to being part of this debate this evening. Looking forward to some interesting questions too

The pipeline of obesity pharmacotherapies looks very promising.
nature.com/articles/s4136…

💤 Sleep & #MAFLD : A much neglected area, but a huge deal to patients‼️
➡️Disrupted sleep REGULATION or ARCHITECTURE ➡️MAFLD.
📌 ⬇️ insulin sensitivity.
📌 ~10%⬆️obesity with every hr sleep lost.
📌 Meta-analysis: short sleep a/w ⬆️ MAFLD.
📌 Poor sleep a/w ⬆️ fibrosis.

Here’s the paper associated with the first drug approved (in US only) for #MASH
Initial points to note..
*MASH only
*not for decompensated cirrhosis
* #diet and #exercise still pinnacle
*only 25/30% saw reversal of NASH
**not a widespread solution**
nejm.org/doi/full/10.10…

First drug for #NASH approved in the US. Recommendation is *still* to have in conjunction with #diet and #exercise intervention #livertwitter

Are we ready to use fermented foods to shape the microbiota-gut-brain axis?

.Ramya Balasubramanian, John F. Cryan & colleagues review the available evidence in the field and suggest solutions to move forward:

sciencedirect.com/science/articl…

🚨High cholesterol is a major risk factor for #MAFLD and #heart disease!
✅ A healthy diet 🍽️ , regular exercise 🚴 🏃‍♀️ and medication 💊 can help reduce it.
#LiverTwitter #MedTwitter

Why aren’t people demanding action on high Dietary Inflammatory Index foods? 🤷‍♂️😉

FREE British Nutrition Foundation webinar: Challenges to achieving nutritional adequacy through a healthy, sustainable diet. 1-2pm (GMT) Thurs 28th March 2024
Register to join the webinar live or watch later nutrition.org.uk/training-and-e…

📨As a former recipient of the British Nutrition Foundation Early Career Scientist Award it is with great pleasure that I share this opportunity with my colleagues
📥Please share with your mentees and collegues and help our community recognize ECRs doing great research 🌟

⬆️ plant protein associated with ⬇️decline in mass and gait speed longitudinally in healthy older adults & ⬆️ animal protein associated with ⬇️ decline in mass with older adults with #sarcopenia 🫘🥜🍗🐟💪
sciencedirect.com/science/articl…

📣When you manage type 2 diabetes with healthy behaviours, you also manage your risk of fatty liver disease, heart disease and kidney disease.
🚨 #MAFLD , Diabetes, heart disease and stroke, and kidney disease are all connected.
#Livertwitter #Medtwitter

Why does the liver deserve the world's attention?

The liver, often overlooked, is one of the most crucial organs in the human body, performing vital functions that maintain our overall health and well-being.

In today's blog we explore the top five reasons why the liver…

Patients with type 2 diabetes mellitus who have non-alcoholic fatty liver disease ( now MASLD) appear to face an increased risk of cardiovascular disease and death from any cause, even when the fatty liver condition is mild.

“NAFLD in patients with T2DM seems to be associated…

🔥Are #heart failure 🫀 and #MAFLD related? 🤔
🆕 Study:
➡️ 98,685 participants; F/U: 14 Y.
📌 MAFLD a/w~1.4-fold ⬆️ risk of HF.
📌 MAFLD #diabetes a/w~ 2-fold ⬆️ risk of HF.
‼️ People with MAFLD with type 2 diabetes require more attention.
#LiverTwitter #MedTwitter