Took us long enough but after 2+ years the thymus team finally managed to meet in 3D. 🎉 Thanks for having me Nadav Yayon Veronika Kedlian!

How can cell atlases of human tissues support drug target discovery? In a joint effort between Teichlab @Sanofi and Ensocell we tested whether info on cell type specific expression from scRNA-seq is associated w targets of clinically successful drugs medrxiv.org/content/10.110…

🕰️ How do you change the time on the most famous clock in #Cambridge ?

The #ClocksGoForward by one hour tonight in the UK, marking the start of British Summer Time. In the heart of Cambridge there is one clock that gets updated in a very interesting way... 🧵

Very exciting aging insights about nucleosome/TFs re-positioning in aged HSC and LINE-element reorganization in HGPS from Jason Buenrostro #singlecellgenomicsday #aging

Our Single Cell Genomics Day - highlighting our favorite new sc/spatial methods - starts Friday at 10AM ET!

The most common question we get: is this open to anyone? Yes! Talks are free and live-streamed (no registration required) on Youtube and satijalab.org/scgd

Really pleased to share our Preprint Club - Immunology #highlight on the #preprint of the Teichlab and Nadav Yayon Veronika Kedlian Lena Boehme, which used a clever approach to yield a detailed #spatial molecular and cellular map of #human #thymic development. Inspiring work, opening new questions.

Causality-enriched epigenetic age uncouples damage and adaptation nature.com/articles/s4358…

Many changes occur with age, but how can we distinguish between causes and consequences of aging?

In my latest article Nature Genetics I evaluate theories of aging from the perspective of causal relationships.

A thread 🧵

nature.com/articles/s4158…

If you are into thymus, quirky TECs❤️, spatial mapping and CCF frameworks-check our preprint below!👇🚨 It was a huge pleasure to pull this off with our creative inventor Nadav Yayon🕵️‍♂️, T cell guru Lena Boehme👩‍🔬, imaging wizard Andrea Radtke🧝‍♀️ our labs and collaborators!!! 🤗🎉

'Decoding aging-dependent regenerative decline across tissues at single-cell resolution' cell.com/cell-stem-cell…

0/10 After Russia's destruction of the dam at Nova Kakhovka, Ukrainians face a manmade calamity amidst the other horrors of Russia's invasion. Ukrainians are at work rescuing their fellow citizens from high waters, often braving Russian fire to do it. Here are ten ways to help.

Ukraine is suffering a manmade calamity amidst a horrible war. People and animals are stranded by the flood. The QR code here will get you to local organizations and people who can help. Please donate.

It is impossible to have any words, besides pure rage, to describe this, given the tremendous ecological and economical impact of this russian terroristic act and the countless human and animal lives being lost to the resulting flooding.

The latest The Economist #podcast reflects on the completion of the Human Genome Project in the early 2000s. Featuring Mike Stratton, Matt Hurles Ewan Birney, discussions explore the next frontiers for genomics in medicine.

Check it out ⬇️

bit.ly/41uBU3Z

I'm extremely delighted that our manuscript on Dandelion is out now at Nature Biotechnology! Nature Biotechnology Teichlab Clatworthy Lab Emma Dann Muzlifah Haniffa roser Wellcome Sanger Institute Cambridge University Human Cell Atlas UQ Medicine Child Health Research Centre go.nature.com/3mxGJuc

Our paper in @nature - a collaboration with Akis Papantonis, Linda Partridge, Antebi Lab, Roman-Ulrich Müller and Thomas Benzing - shows that the average RNA polymerase II speed increases with age. nature.com/articles/s4158…
nature.com/articles/d4158…

It’s minutes after 5 am in Kyiv and this is the moment when it’s been exactly one year since this nightmare started.

On the highway towards Human-Level AI, Large Language Model is an off-ramp.