Reclaiming the Labcoat with Sadye Páez (she|her|ella). More on this soon.

An AMAZING presentation

of Alexander Wittenberg

In the T2T UL Webinar

Oxford Nanopore
TheLongReadMaster

Tomorrow!
ucsc-seqtech-events.online

Join an open webinar on April 4th (12-4pm Eastern Time) to explore the nuances of ONT-UL data production and its application in ongoing T2T projects.
Register here: ucsc-seqtech-events.online

Happy to represent KeyGene as speaker at the UC Santa Cruz Genomics Institute Sequencing Technology Center, Oxford Nanopore Ultra-long sequencing and applications​ webinair; ucsc-seqtech-events.online

Registration open for the T2T Oxford Nanopore Ultralong workshop online next week organized by Karen Miga and Adam Phillippy. Open to all to hear the latest advances in ultralong preps and applications! ucsc-seqtech-events.online/?utm_campaign=…

Join hosts Karen Miga & Adam Phillippy as they bring together experts from around the world to share their insights into telomere-to-telomere ( #T2T ) assembly, and highlight the advantages, breakthroughs and obstacles of ultra-long sequencing.

Register: bit.ly/3PFTa2f

Want to learn more about the tricks and tips for generating ONT Ultra-long DNA? The T2T Consortium and UCSC SeqTech Center are hosting a Technology-focused Webinar next Thursday with a group of experts.
Register today: bit.ly/3PFTa2f Adam Phillippy

So excited to have this preprint out! Severus is a new tool for somatic SV calling in cancer using long reads. It supports tumor/normal analysis, takes advantage of long-read phasing and can cluster and annotate complex SV events. medrxiv.org/content/10.110…

This work is dynamite ; ) Karen Miga Alexander Wittenberg Sergey Koren Sara Goodwin Michael Schatz Adam Phillippy showcasing that gapless assemblies are possible on one platform Oxford Nanopore. We are driving our technology to deliver this with fewer and fewer flow cells...bring on V2 of this! Congrats!

Happy to share our preprint from Ali Shariati علی شریعتی lab at UCSC Biomolecular Engineering! Using inducible CRISPR-activation tools, we can instruct mouse embryonic stem cells to form spatially ordered embryonic patterns in 2D and 3D under simple growth conditions: biorxiv.org/content/10.110… #CRISPR

For all those wondering about the next H3ABioNet Introduction to Bioinformatics course, applications for participants are now open, follow the links below!

Lab’s first research article on mouse centromeric satellites and chromatin by our star Emory College
alum Jenika Packiaraj is now published in Genome Biology . Many, many congratulations, Jenika! genomebiology.biomedcentral.com/articles/10.11…

We have an exciting new venue and programme that includes keynote Rebecca Heald, panelists/discussion leaders so far including Karen Miga, Gary Karpen, Simona Giunta, Jessica Fellmeth, Patrick Heun and Bradley French (Novartis, formerly Aaron Straight lab). More to follow!

It's time!

Where? Grand Sierra Ballroom D&E

What? Hear me talk on our work using #ACME - an Affinity-based Cas9 Mediated Enrichment method on Oxford Nanopore that captures ~100kb on-target reads and it's application to look at interesting CRC organoids!

#AGBT24

Six weeks left until the abstract deadline for Biology of Genomes at CSHL #BoG24 ! We have a stellar lineup of keynotes and discussion leaders (=~invited speakers), and look forward to another brilliant meeting in May 7-11. Abstract submission & info:
meetings.cshl.edu/meetings.aspx?…

Our paper about nucleolar stress induced by anticancer drugs has snagged a spotlight in the eLife digest elifesciences.org/digests/88799/…

Check out our latest review | LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities by Carlos Mendez-Dorantes.
Our thanks to Genes & Development.
genesdev.cshlp.org/content/early/…