Olli Dufva
@ollidufva
MD, PhD, postdoctoral fellow @sangerinstitute, previously @helsinkiuni. Functional genomics in immunology and cancer
ID:813802186249555969
27-12-2016 17:42:15
1,0K Tweets
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Happy to share that our work on identifying efficient strategies to target the BCR::ABL1 independent pathways in chronic myeloid leukemia is now out in Cell Reports Medicine
Aricle: cell.com/cell-reports-m…
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Happy to share our work Inflammatory and subtype-dependent serum protein signatures predict survival beyond the ctDNA in aggressive B cell lymphoma sciencedirect.com/science/articl… just published online in #CellPress journal #MED Leo Meriranta Suvi-Katri Leivonen Mats Jerkeman
Happy to share our work Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-cell Lymphoma just published online in Blood Cancer Discovery aacrjournals.org/bloodcancerdis…
Thank you for fantastic team work Leo Meriranta & Selma Sorri and collaboration Myklebust Lab Varjosalo_Lab
An elegant and exciting example of how functional genomics - CRISPR and base editing screens - can help direct drug development in oncology.
Congratulations Garnett Lab, Gabriele Picco and colleagues!
doi.org/10.1158/2159-8…
Our work 'Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells' is published today in Cancer Discovery (aacrjournals.org/cancerdiscover…). Using genetic tools, in 2019 Cancer Dependency Map Sanger and others reported WRN as a synthetic-lethal target in MSI cell line. 1/5
Big couple of days for the team at #AACR24 . Mathew Garnett will be presenting *today* on the development of an organoid biobank for dependency mapping. Ballroom 20CD at 13:25. Also, don't miss Gabriele Picco tomorrow presenting novel WRN helicase inhibitors.
So happy to share my PhD work published today nature ! We studied how tissue niches shape Treg function. So grateful to Fiona The Powrie Lab, Emily Dr Emily Thornton and a wonderful collaboration with Sarah Teichlab and Raquel Raquel Bartolomé-Casado. We did it! nature.com/articles/s4158…
EUROPEAN HEALTH REGULATIONS REDUCE REGISTRY-BASED RESEARCH
PREPRINT medrxiv.org/content/10.110…
How do privacy laws impact medical research and innovations? Should we be concerned about the #EHDS ?
@ennisanmark ilarikuitunen @vponkilainen @aleksireito Joonas Kauppila
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Are meningeal lymphatics important in #Alzheimer ? 🧠
Excited to share our new story out Nature Cardiovascular Research
👉 rdcu.be/dBkoT
Contrary to previous results, we show that manipulation of meningeal lymphatic vessels does not alter Alzheimer’s disease-related amyloid pathology
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OBS #Cancer #Immunology Seminar
📆 Tu, March 19, 1 pm ET / 17h GMT / 18h CET
🎙️ Dr Olli Dufva
Olli Dufva
University of Helsinki Medicine and Health, University of Helsinki HRUH hematology
Wellcome Sanger Institute
Immunity
✍️ us02web.zoom.us/meeting/regist…
#openscience
OBS Seminar Immunology
📆 Tu, March 19, 1 pm ET/17h GMT
🎙️ Dr Olli Dufva Olli Dufva
University of Helsinki Medicine and Health, University of Helsinki HRUH hematology Wellcome Sanger Institute
🎙️ Dr Priyadharshini Devarajan Priya Devarajan
✍️ us02web.zoom.us/meeting/regist…
Moderator: Anna Salamero Boix Lisa Sevenich Lab
#openscience
Excited to share our latest work now published Nature Communications characterizing the role of IFNg signaling in AML and its implications on AML differentiation, therapy resistance, and immune microenvironment.
Bofei Wang Hussein Abbas
nature.com/articles/s4146…
Nice work from Patrick Reville, MD, MPH and colleagues. HLA-E expression on AML blasts higher in cells with monocytic differentiation, del7/7q. Driven by IFN-gamma enabling NK evasion via interaction with NKG2A. See also doi.org/10.1016/j.immu… from Olli Dufva Sara Gandolfi
