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Expression of genes involved in processes related to CVD risk were differentially altered between the groups. This included genes related to vascular smooth muscle cell proliferation (FGF18, SEPTIN4), LDL-receptor folding (DNAJC10) and blood pressure regulation (ATP2B1).

#LeukemiaStemCells ( #LSC ) are responsible for the initiation, development, and relapse of #acuteMyeloidLeukemia ( #AML ). #DNAJC10 , an #ER #co -chaperone, emerged as an independent predictor of survival in AML.
haematologica.org/article/view/h…

DnaJ (Hsp40) homolog, subfamily C, member 10 (DNAJC10) (Human) antibody: Gentaur antibodies biotechnology :DnaJ ... bit.ly/V2xMjQ

bit.ly/AtdScY DNAJC10 #random

Upregulation of JHDM1D-AS1 protects PDLSCs from H2O2-induced apoptosis by decreasing DNAJC10 via phosphorylation of eIF2α. zpr.io/gJ9rt

New research reveals that DNAJC10, a member of HSP40 family, functions as an #oncogene in MLL-AF9-induced #AML via regulation of the PERK branch of the unfolded protein response, maintaining the survival and self-renewal of leukemia stem cells.
bit.ly/435u7vi

How do #leukemia stem cells maintain their leukemogenic activities and respond to stress? 🤔

DNAJC10, a member of HSP40 family, has a crucial role to play in it.

🔎 Find out in Haematologica.
bit.ly/44QXykx

#バイオ関連ニュース 京都産業大学の永田和宏教授らの研究チーム、小胞体のカルシウム濃度の制御に関わる、小胞体上のカルシウムポンプの調節因子を同定 ≫bit.ly/2cYRr6a　ERdj5（DNAJC10） ≫bit.ly/2cO8JEM

A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic… dlvr.it/PyqsXt

Participant 205: 5-year-old male with global developmental delay, generalized low muscle tone, recurrent respiratory infections, and variants in #DNAJC10 .

Reach out if you know of others with similar symptoms and a variant in this gene!

undiagnosed.hms.harvard.edu/participants/p…

A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic… dlvr.it/PyrvFc #PH