Get ready for 2024 Virtual Virtual ChemBio Talks ! Fantastic opportunity for #PhD and #postdoc to share your research on a global platform. Applications due July 31st, 2024 #chembiol #chemicalprobes #chemicalproteomics
…mistry-europe.onlinelibrary.wiley.com/hub/journal/14…

Interested in #chemicalproteomics and developing #chemicalprobes with unique mechanisms of action? Funded #PhDposition Universiteit Leiden for project on #allosteric #drug discovery. Cell, #chemicalbiology , #proteomics exp. preferred. Apply by email w/ CV, prior research & rec. letter 🙂

Pleasure to host the first ever Chemical Probes Hackathon here at the Merck headquarters today. chemicalprobes.org/hackathon
#unitedbyscience #hackathon #chemicalprobes
Chemical Probes Portal Merck aled edwards

Happy for sharing our most recent (open access) review paper! Universität Tübingen
Check it out!
Ps: my first as corresponding author 😊
doi.org/10.1016/j.crch…

#ChemicalProbes
#MedicinalChemistry
#ChemicalBiology
#DrugDesign
#DrugDiscovery
#CovalentInhibitors
#CovalentWarheads

📢 Join us for our upcoming #Target2035Webinar , highlighting the alarming lack of best practices with #chemicalprobes in biomedical research.

🌐 Free registration: ki-se.zoom.us/webinar/regist…

Let's raise awareness and improve the use of chemical probes together!

📢 👏 Cheryl Arrowsmith, Matthieu Schapira and Dalia Barsyte have been awarded more than $3 million from CIHR.
Read more: bit.ly/3P5KZfj
#CancerResearch #DrugDiscovery #ChemicalProbes , #AI

[Publications Update]
Lab: Hidenobu Mizuno

Title: In vivo two-photon calcium imaging of cortical neurons in neonatal mice 🔬🐁

Read here⏩ircms.kumamoto-u.ac.jp/publications/2…
#Bioinformatics #CellBiology #DevelopmentalBiology #ModelOrganisms #Molecular #ChemicalProbes #Neuroscience

ACS Publications Bio & Med Chem Content New scaffold to explore ADP-ribose metabolism: By performing SAR studies, we identify a first-in-class, non-covalent dual inhibitor for NUDT5 and NUDT14. (5/5)
📖Read the full story here: pubs.acs.org/doi/10.1021/ac…
#CovalentInhibitors #ChemicalProbes #DarkProteome

Great #chemicalprobes meeting with John Spencer Lab - keep those compounds a-coming!

📢 Only 1 week left until the highly anticipated Target 2035 webinar!
🌐 Free registration: ki-se.zoom.us/webinar/regist…
Let's raise awareness and improve the use of chemical probes together 🧪🔬 #Target2035Webinar #ChemicalProbes #BiomedicalResearch

Great British Pharmacological Society event coming up on #covalent #drugs #chemicalprobes . Exciting program including Dan Nomura London Lab Emma Grant @scorpionTx Vividion Therapeutics Lyn Jones Monique Mulder Matthews Group and more!

🛫On the way to #AACR23 and can’t wait for the latest research and small molecule disclosures!
Catch us at Booth #1763 to see what Tocris Bioscience have been up to recently in: #CancerMetabolism , #Epigenetics and our latest compound libraries! #OpenScience #CancerResearch #ChemicalProbes

🔬 Join the 13th International Activity Based Protein Profiling Meeting! 🔬

📅 July 17-19, 2023
📍 The David Lopatie Conference Centre Weizmann Institute of Science, Israel
🌐 conferences.weizmann.ac.il/ABPP2023/

#ABPP2023 #BasedProteinProfiling #ChemicalProbes

Exited to be at #AACR24 gearing up for the 1st session of the educational program: Are you targeting your protein? #ChemicalProbes #DrugDiscovery

Recent advances in the development of covalent inhibitors - now published in RSC Medicinal Chemistry pubs.rsc.org/en/content/art………………… #chemistry #Bioinformatics #ChemicalProbes #MedicinalChemistry

Don't miss our next MedChemBioOnline on 'Best Practices in hit-to-lead Optimization' - September 26th, 16:30 CET! Stay tune for the great line-up of speakers. For registration (free): medchembio.online/registration
#MedChem #Hits #Lead #BestPractices #drugdiscovery #chemicalprobes

Congrats! Impressive numbers highlighting the impact of this pre-competitive initiative. Great fun to be part of it. More #chemicalprobes and exciting science to come… #openscience #Target2035 Structural Genomics Consortium (SGC) The SGC Frankfurt

Catch the poster from the Chemical Probes Portal at session PO.BCS01.09 on Database Resources, Statistical Methods, and Other Tools. Don't miss this valuable resource! #ChemicalProbes #AACR2024

#Chemical_probes
📌Chemicalprobes are powerful reagents with increasing impacts on biomedical research. However, probes of poor quality or that are used incorrectly generate misleading results.
📌Within druggable target space, new…lnkd.in/gVcnE6Tp lnkd.in/gccx_KeA

📢Stefan Knapp from The SGC Frankfurt has been granted €11.8M for developing pharmacological strategies to modify the abnormal transcriptional programs in cancer cells. Read more: thesgc.org/news/frankfurt…
#CancerResearch #DrugDiscovery #ChemicalProbes