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From the January-March 2024 Issue of #Neurographics : Spectrum of Neuroimaging Features of Histiocytosis Syndromes in Children ow.ly/AWK150Rsy5t

This new review covers the current understanding of Langerhans cell histiocytosis biology and opportunities to improve outcomes for every patient through coordinated agent prioritization and clinical trial efforts.

acsjournals.onlinelibrary.wiley.com/doi/full/10.10…

OncoAlert

Langerhans cell histiocytosis:
-Letterer-Siwe disease: systemic multiorgan disease, often in very young
-Hand-Schüller-Christian disease: multiple local lesions, often in one organ system (usually bone)
-Eosinophilic granuloma: solitary lesion, best prognosis
#radres #radiology

Erdheim-Chester:
-multisystemic histiocytosis, but not part of Langerhans cell
-lung (usually cystic), renal (hairy kidney sign), retroperiteonal (coated aorta with IVC sparing), rtetroorbital, cardiac, and intracranial involvement (hypothalamus most common)
#radres #radiology

ALK positive histiocytosis with multiple system involvement: report of a case dlvr.it/T67lbL

Langerhans Cell Histiocytosis Mimicking a Meningeal Lesion with Temporal Bone and Muscle Compromise in an Adult Patient: A Case Report dlvr.it/T6GG7v

Congenital self-healing Langerhans cell histiocytosis with pulmonary involvement: spontaneous regression dlvr.it/T6GYQF

A rare diagnosis of Langerhans cell histiocytosis made on thyroid histology with coexisting papillary thyroid cancer and AVP deficiency dlvr.it/T5zZJ3

Two weeks ago, we shared a video in which Deanna sat down with docs from Mayo Clinic and UAB Medicine to discuss the pathology of Malignant Histiocytosis, a rare from of histiocytosis.

See the Clinical video here on our YouTube channel: youtu.be/YGTwP5c_piM

Rosai-Dorfman disease/sinus histiocytosis with massive lymphadenopathy:
-classic massive painless lymphadenopathy (cervical neck most common) in young adult with B symptoms
-also common: enhancing meningeal masses; can also affect skin, lungs, orbit, kidneys, bone
#radres

Check out this interview on clinical management of malignant histiocytosis by my awesome colleagues Gaurav Goyal & Gordon Ruan, MD, in conversation with Histiocytosis Assoc
#letstalkhistiocytosis

Paediatric Haematology/Onc Lecture: Management of Langerhans Cell Histiocytosis
Speaker: Dr R Dowse
📅8 May
⏰13-14.00 Pakistan
9-10 GMT+1
us02web.zoom.us/j/81217276170?…
Audience:
Pediatric Haematology Onc Fellows, consultants,
Nurses, Pediatricians, Pediatric Residents, Bone Marrow

Exploration of treatment in childhood Langerhans cell histiocytosis based on inflammatory and malignant symptoms: a pilot study dlvr.it/T6181D

Dr Ihab Suliman. دكتور ايهاب فتحي سليمان Bilateral Hilar Lymphadenopathy:-
Ddx-sarcoidosis,Infections(TB,mycoplasma),Malignancy-primary lung tumours or metastatic,Organic dust-silicosis,Berryliosis, Histiocytosis,Hypersensitive pneumonitis.

Check out this webinar on Histopathologic challenges and pitfalls in diagnosing Malignant Histiocytosis. Hosted by the Mumbai Hematology Group; in collaboration with Histiocyte Society & Histiocytosis Assoc #letstalkhistiocytosis #rarediseaseawareness

youtube.com/live/mgAWBc0rb…

Jason Garringer William Makis MD No. It's cancer. A kind of Histiocytosis, which are all extremely rare. Histiocytes are a type of white blood cells in our immune system.

Dr Ihab Suliman. دكتور ايهاب فتحي سليمان The differential diagnosis of papular acrodermatitis includes other viral exanthems such as erythema infectiosum and hand,foot, and mouth disease, insect bites,scabies, papular urticaria, atopic dermatitis,erythema multiforme, Langerhans cell histiocytosis, lichenoid dermatoses,