Thanks Prof Rebecca Ritchie and thanks to AJP-Heart and Circ for the chance to contribute this editorial on some very exciting #macrophage - #fibrosis work! See the full paper from Neff. et al at journals.physiology.org/doi/full/10.11… + our commentary at journals.physiology.org/doi/full/10.11… CU Cardiology CSD Graduate Program
Hello again, Newcastle. Always a pleasure. Looking forward to sharing our screening efforts to unpick macrophage metabolism BSI Immunometabolism #UKimmunomet24
Excited to share our latest findings researchsquare.com/article/rs-422… discovering how the microenvironment regulates extracellular fluid sampling by #macropinocytosis via the environmental dimensionality, adhesiveness, & actin network utilisation.
Movie: macrophage on micropatterns
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Great to be invited to speak at #BSR24 by BSR on our work on macrophage modulation, immunocompatibility, and promote SINPAIN
Lots of interest and new collaborations.
Inst of Systems, Molecular & Integrative Biology Faculty of Health and Life Sciences P&T_UoL
IL20Rb, a cell-surface receptor that belongs to IL-20 family, aggravates pulmonary fibrosis through enhancing bone marrow derived profibrotic macrophage activation in vitro: doi.org/10.1016/j.phrs…
#pulmonaryfibrosis #macrophage #PharmacolRes #openaccess #Research #PharmaTwitter
TREM2 as a positive regulator of Macrophage #FoamCell mitochondrial function, survival & efferocytosis under hypercholesterolemic stress
Hematopoietic TREM2 KO⏫ #NecroticCore formation in early (8~12 wk), not late (16~20 wk) #Atherosclerosis in Ldlr-/-🐭
w/o altering lesion or
Last month, Tobias Stöger from Helmholtz Munich | @HelmholtzMunich gave a talk on macrophage dynamics during nanoparticle triggered lung inflammation in mice, during the European Phagocyte Workshop 2024. 🦠🔬🧬🐁👩🔬🫁
Read more about it here: harmless-project.eu/harmless-at-eu…
#cells #inhalednanomaterials
So excited to share my postdoc work in Apte Lab of WashU Ophthalmology Washington U. Med @WUSTL ! Therapeutic approach targeting NAD+ depletion and cellular senescence against aging retina and early-stage AMD. cell.com/cell-reports/f…
🚨My PhD work is out in JACC Journals !! Using a translational approach, we highlighted the importance of MCP-1 and IL-6 and their role in macrophage recruitment and polarization! 🫀
jacc.org/doi/10.1016/j.…
Great talk by @SungYeon___Kim on macrophage diversity in the fibrotic synovium at #OARSI2024 ! For more information on these and related studies please visit posters 659, 695 and 755.