We’re excited to announce that Bristol Myers Squibb acquired Orum’s ORM-6151 program, a first-in-class, anti-CD33 antibody-enabled GSPT1 degrader for acute myeloid #leukemia or myelodysplastic syndrome.

orumrx.com/news/orum-orm-…

#oncology #targetedproteindegradation #ADC #AML

Unleash #ML in #MaterialScience ! Learn from Dr. Rodrigo Albuquerque on designing new epoxy resin materials & predicting properties. Don't miss this chance! #DrugDiscovery #InflammatoryDiseases #TargetedProteinDegradation
14 Feb, 1200 Hrs at SINES Auditorium #Event

Met another real life superhero Jay Bradner, M.D. of ours today 😊Keystone Symposia

#ProximityBasedTherapeutics #TargetedProteinDegradation
#KSProteinDeg24 #KSProximityTx24 #keystoneconferences

Orum Therapeutics Unveils New Program at #AACR23 , Highlighting Cbl-b Inhibitor-PD-1 Conjugate, and Presents New Data Supporting Clinical Development of Two GSPT1 Programs

bit.ly/3A2KCdw

#immunooncology #targetedproteindegradation #cancer #oncology

We conducted two screens with different targets, exogenous and endogenous, and different readouts to find novel effectors for #targetedproteindegradation .

#February11 is International Day of Women and Girls in Science, a time to honor the #WomenInStem blazing the trail for a more equal future. Thank you to all women on the #C4TxTeam who work each day to advance our groundbreaking discoveries in #targetedproteindegradation !

#Targetedproteindegradation is a new therapeutic approach that has the potential to #targetdisease causing proteins that have historically been difficult to target with conventional small medicines.
For more details: [email protected]

Conventional anti-cancer therapies often fall short. At Captor Therapeutics, we're changing the game with targeted protein degradation therapy. Earmark cancer-causing proteins for elimination. A new hope for cancer patients.
#cancerresearch #targetedproteindegradation

New Year, new website!

We refreshed our site to reflect Kymera’s exciting advances and #innovation in the field of #targetedproteindegradation and showcase how we’re working toward our vision to reinvent disease treatment and deliver life-changing medicines to patients.

Aitana De La Cuadra Baste, Aitana de la Cuadra Baste, sharing our outreach activity in 2023 UoD Life Sciences Annual Research Symposium. We won a School Public Engagement Prize in recognition of this work.

#CeTPDInspire #TargetedProteinDegradation

Jan 2023 #CeTPD #JournalClub is out!
lifesci.dundee.ac.uk/groups/alessio…

Congrats to editors
Kevin Haubrich

Sohini (she/her)

Yuting Cao

Thanks
Charlotte Crowe

Alessio Ciulli
for contributing to the feature of the month.

University of Dundee

UoD Life Sciences

#TargetedProteinDegradation

So glad I have non-chemistry friends so I can create gems like these to explain what I do
#TargetedProteinDegradation

【今週のイベント】

いよいよ、ファイメクス主催の TPD Conference が今週開催！
海外からの Keynote Speaker もお呼びしての本格的なプログラムで、多くの参加申込が来ているようです。

#片山化学 #東ソー
#ファイメクス #TargetedProteinDegradation
#ScienceCafe #組織移行性抗体
#湘南アイパーク

Meet with our colleague Brent Passer at the 2nd Molecular Glue Drug Discovery and Development Summit in Boston to discuss about your #TargetedProteinDegradation projects and our technology platforms. With our 25 years’ experience in #PPI screening and characterization and

Our platform for rapid manipulation of endogenous proteins at scale #SPOTLITES can be employed to discover novel effectors for #targetedproteindegradation #TPD and other proximity-based approaches!
biorxiv.org/content/10.110…

#Ubiquitin is really amazing. Virtually unchanged during eukaryotic evolution, it has generated thousands of functionally related genes, including hundreds of ubiquitin ligases, and is involved in almost all events related to #proteostasis . #Targetedproteindegradation ( #TPD )

Beautiful review of lysosomal degraders ⁦nature⁩ #degraders #targetedproteindegradation nature.com/articles/s4158…

New steps expanding #targetedproteindegradation ( #TPD ) to tackle neurodegenerative diseases. #synucleinopathies
pubs.acs.org/doi/10.1021/ac…

Next week at the RICT International Conference on Medicinal Chemistry event in Lille, France, Rohan Beckwith, our Vice President of Chemistry, will be presenting on approaches to molecular glue discovery

#RICT2023 #TargetedProteinDegradation #molecularglue #medicinalchemistry

We look forward to #TechBio UK tomorrow in London! 🌐 If you're interested in learning more about our #AI -driven platform, how #CelerisTx leverages data to drive its pipeline, and our team of #TargetedProteinDegradation (TPD) experts, reach out to Honorine at TechBioUK! 🤝