Check out a new review series: Lymphatic System in Organ Development, Function, and Regeneration UMass Chan Medical School Department of Medicine Circulation Research ahajournals.org/doi/10.1161/CI… Outstanding reviews from Oliver Lab Caron Lab Petrova Lab – Vascular and Tumor Biology Ulvmar lab Elaine Shelton Annet Kirabo D.V.M., M.Sc., Ph.D., F.A.H.A. & Valentina Kon!

Very excited to share our recent work published as the cover story JCI insight insight.jci.org/articles/view/… Fantastic collaboration UMass Chan Medical School UMass Memorial Health Department of Medicine UMass Chan Cardiology Fellowship NAVBO

#Cover : Pathological activation of MAPK causes lymphangiectasia treatable with ravoxertinib: buff.ly/3RFn7y1
Image: H&E-stained pathological human tissue section that shows lymphangiectasia.
Trivedi Lab Department of Medicine
#Development #VascularBiology

Checkout a new comprehensive review series on vascular and lymphatic malformations Circulation Research AHA Research NAVBO EVBO Endothelial Cell News ahajournals.org/doi/10.1161/CI…

Our recent manuscript showing YAP1 drives epithelioid hemangioendothelioma is published as the Cover story of July 2021 issue of ATVB: An AHA Journal @UMassMedical Wonderful collaboration with @UMassMedMCCB UMass Memorial Health ahajournals.org/doi/10.1161/AT…

Our recent study by Roy Jung et al Trivedi Lab @UMassMedical @GSBS_UMassMed Department of Medicine show 'Sustained Activation of #Endothelial #YAP1 Causes #Epithelioid_Hemangioendothelioma ' ATVB: An AHA Journal Wonderful collaborators UMass Memorial Health @UMassMedMCCB
ahajournals.org/doi/10.1161/AT…

Recent work from our lab Trivedi Lab @UMassMedical @UMassMedCancer @GSBS_UMassMed is published as Cover in July issue of JExpMed Fantastic collaboration with UMass Memorial Health

Harish Janardhan in our lab Trivedi Lab @UMassMedical show #KRAS or #BRAF mutations cause #hepatic #vascular cavernomas treatable with MAP2K-MAPK1 inhibition JExpMed #vascular biology #hemangioma #endothelialcells doi.org/10.1084/jem.20…

This study by Harish Palleti Janardhan, Trivedi Lab, et al. @UMassMedical @GSBS_UMassMed NAVBO demonstrates endothelial KRAS or BRAF gain-of-function mutations as a causal mechanism for hepatic vascular cavernomas bit.ly/3dIqnEY

A recent study from our lab @UMassMedical @GSBS_UMassMed shows Hdac1/2 silence cryptic transcription to promote mitochondrial function and energy production in heart Science Advances Awesome collaboration with Cole Haynes
advances.sciencemag.org/content/6/15/e…

Establishment and maintenance of blood-lymph separation. - PubMed - NCBI ncbi.nlm.nih.gov/pubmed/30758642

JCI - Hdac3 regulates lymphovenous and lymphatic valve formation jci.org/articles/view/…

Hdac1/2 are essential for neural crest proliferation, pharyngeal arch development and craniofacial morphogenesis. - ncbi.nlm.nih.gov/pubmed/28791750

HDAC3-mediated epigenetic silencing of TGF-β1 is required for normal heart development - NCBI ncbi.nlm.nih.gov/pubmed/26420484

Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis. - PubMed - NCBI ncbi.nlm.nih.gov/pubmed/2456586…