We honored John T. Harty Lab as the 2023 Ingraham Lecturer. He was hosted by former postdocs MJ Richer and Nathan W Schmidt
Super happy to share our new review on CD8 T cells and malaria! And to celebrate my foray back into mosquito borne diseases 🎉 John T. Harty Lab Sahaana Arumugam
onlinelibrary.wiley.com/doi/10.1111/im…
How are lung Trm affected by thorax-targeted radiation? Are there ways to regenerate them? Find out the answers from this 3-min video summay from Dr. Mariah Hassert John T. Harty Lab
The John T. Harty Lab from Carver College of Medicine found that sublethal thorax-targeted radiation resulted in the rapid and prolonged numerical decline of influenza A virus–specific lung tissue-resident memory T cells in mice. 🐁
🖨️ JExpMed
Learn more: bit.ly/49EY8nF
#JI_TopRead from John T. Harty Lab University of Iowa Pathology | #IFNgamma derived from CD4 #Tcells limits parasite burden in chronic stage #malaria l infections | #ReadTheJI #immunology #malaria #parasiteimmunology #plasmodium 👉 ow.ly/FpmV50NNr0r
Hassert et al. John T. Harty Lab UIowa Research show that thorax-targeted irradiation depletes lung resident memory CD8+ T cells (TRM) & diminishes protection, but spares circulating memory CD8+ T cells that can be boosted to regenerate lung TRM. hubs.la/Q02llkpJ0
Aliasger Salem
#CuttingEdge from John T. Harty Lab University of Iowa | Simultaneous detection of both airway and interstitial #influenza -induced CD8+ tissue-resident memory #Tcells in mice shows compromised #IFN -γ production upon challenge
👉 ow.ly/jVBe50NEp8X
In JExpMed, Hassert et al. John T. Harty Lab UIowa Research show that thorax-targeted irradiation depletes lung resident memory CD8+ T cells (TRM) & diminishes protection, but spares circulating memory CD8+ T cells that can be boosted to regenerate lung TRM. hubs.la/Q02llFMG0
Regenerating murine CD8+ lung tissue resident memory T cells after targeted radiation exposure. A new study by Mariah Hassert, John T. Harty John T. Harty Lab and colleagues UIowa Research: hubs.la/Q02llb1f0
Aliasger Salem
#InfectiousDisease #HostDefense
In this report, Hassert et al. John T. Harty Lab UIowa Research suggest that designing effective vaccination strategies to regenerate TRM will be important in combating the immunological effects of radiation exposure. hubs.la/Q02mqVnK0
🎥 See video summary: hubs.la/Q02mqW1T0
Keeping T cell memories in mind.
Check out this Trends in Immunology review of emerging literature on the generation, localization, maintenance, and function of tissue-resident memory T cells in the central nervous system, from John T. Harty Lab #SfN23 hubs.li/Q028x3xJ0
Dr. John Harty was awarded a grant entitled “Regulating Pathogen-induced Protective and Pathogenic CD8 T cells in the CNS” from NIAID Funding
medicine.uiowa.edu/pathology/cont…