Call for collaboration on #MSMO1 deficiency. Please contact us if you have patients with homozygous/biallelic variants Sofia Douzgou Houge Kakha Bregvadze, MD Gunnar Douzgos Houge ERN-ITHACA
ern-ithaca.eu/for-clinicians…

Proud to share our new publication in Frontiers about founder mutation in COL4A3 gene resulting in #Alportsyndrome and #TBMD . There is so much more to dicover in Georgia's isolated sub-population with high consanguinity rate. Kakha Bregvadze, MD Eka Kvaratskhelia Elene Abzianidze

Presented at XII Georgian National Congress on Allergy, Asthma & Immunology. Discussed how genomics-based diagnosis and therapy can be helpful in dermatology clinical practice.

I finished my talk with McKusick's quote. He was absolutely right.

Is #minoxidil the game changer The New York Times suggests? How can we get better data to help guide patients through their #alopecia journey? My interview with Benjamin Hart in New York Magazine's Intelligencer. nymag.com/intelligencer/…

Lives are ruined by inappropriate use of food allergy tests.

These were never designed to be used as screening tests, yet they're often used as such.

It is backwards & incorrect to perform a panel, then make a diagnosis regardless of history.

I spend my days undoing this harm.

Another provocative study by Joann Elmore, MD, MPH et al showing that dermatopathologists are influenced by the diagnosis of a previous dermatopathologist. This can even influence them to make an INCORRECT melanoma diagnosis. jamanetwork.com/journals/jamad…

NEW research published by The BMJ today identifies important differences in monkeypox symptoms between the current outbreak and previous outbreaks in endemic regions bmj.com/content/378/bm…

All the #dermatology #match22 resources here for you!

✔️ Association of Professors of Dermatology statement: students-residents.aamc.org/media/12386/do…

✔️ National Dermatology Interest Group Association Association of Professors of Dermatology webinar: bit.ly/DIGAxAPDwebina…

✔️ Google doc w program info (evolving!): bit.ly/DermMatch22Pro…

Best of luck to all the applicants! x

This tweet got a bit derailed by the attempted coup yesterday...but Gil Welch, Benjamin Mazer and me in this week's NEJM where we explain how UV exposure CAN'T explain the rapid rise in melanoma which is likely an epidemic of diagnosis and NOT disease nejm.org/doi/full/10.10… THREAD👇🏾

Our new paper is out today. We used CRISPR to uncover some really striking findings with several drugs and drug targets in clinical trials. Also, we accidentally found the first-ever inhibitor of the cyclin-dependent kinase CDK11. stm.sciencemag.org/content/11/509…

As scientific racism is repackaged for the age of DNA databases and polygenic scores, the geneticists whose research is giving it oxygen are struggling with how to respond. My latest: nytimes.com/2018/10/17/us/…

Arash Mostaghimi grand rounds has started! #medtwitter #dermatology How do we approach data in dermatology?

In rare occasions, dark-skinned people can get skin cancer. But sunscreens won’t help. - The Washington Post wapo.st/2I4eFWP My article made it to my hometown paper 🤯🤯🤯

Effect of Sunscreen Application on Plasma Concentration of Active Ingredients bit.ly/2vD3w9V This provocative study in JAMA about sunscreen deserves a #tweetorial . Bear with me as I take you through the controversy and discuss sunscreen in general. 👇🏾👇🏾👇🏾

Allergy skin testing places a drop of liquid allergen (pollen, food, etc) on the skin then gently scratches through to introduce to the cells in the skin.

If specific IgE is present, histamine is released = itchy raised bump & redness.

Results are ready in 15 minutes(thread⬇️)

Key points:

Bath emollients, silk garments & antihistamines - no benefit in atopic eczema

Topical steroids just as effective used once daily as twice daily

Best way to treat AE: mometasone furoate OD + oral antibiotics if severely infected + dermol

#kingsgenpaeds19

“Hi, doctor. I am here because I have a mast cell disorder.”
“Do you have a penicillin allergy?”

Mariana Castells recommends you assess, diagnose, and de-label, if possible, every patient.

New role for the modern allergist in drug allergy annallergy.org/article/S1081-…

Medicine-Based Evidence: this essay by Ralph Horwitz and colleagues is a worthwhile read for the critics who believe EBM is the be-all-and end-all for caring for individuals American Journal of Medicine amjmed.com/article/S0002-… open-access (and I support EBM, while acknowledging its limitations)

This study is yet another one in a growing list demonstrating that dysplastic nevi are NOT obligate precursor lesions for melanoma. Let me give you a brief history/discussion of the 40 year old controversy.

A thread/ #Tweetorial 👇🏾👇🏾👇🏾

In need of evidence about acne, atopic eczema, cellulitis, psoriasis or vitiligo? We've got you covered: buff.ly/2Iurpp4 … -

All systematic reviews from the past 18 years, organised by topic. Updated monthly, Free to view.

You're most welcome to RT and share.