How do we know which patients with #gastriccancer benefit most from immunotherapy? PD-L1? We thought that as the score goes up, so does magnitude of benefit. Unfortunately that doesn't seem to be the case. We write about this thelancet.com/journals/langa… The Lancet Gastroenterology & Hepatology Lizzy Smyth

2023 brought a few news in upper GI Oncology:
-ICIs+ChT in the peri-op stage
-An early look at non-operative management in complete responders to CRT
-Pembro-Trastuzumab+ChT in HER2+/PD-L1+
-New targets (CLDN18.2) and combinations (TFOX)
A wrap-up here: bit.ly/3UjvzYk

Moving to ultra-short therapy to cure patients with cancer: a solution for sustainable cancer care. Don’t miss the editorial by Drs. Ribeiro, Dixon-Douglas and FabriceAndre that accompanies the latest issue of ESMO Open.
esmoopen.com/article/S2059-…

Pleased to share PAGA guideline for #gastriccancer . Really appreciate Asian & European experts Lizzy Smyth Tania Fleitas Kanonnikoff George Pentheroudakis Andres Cervantes who joined the discussion. Thank you ESMO - Eur. Oncology and 日本臨床腫瘍学会（JSMO） for excellent support. esmoopen.com/article/S2059-…

Tania Fleitas Kanonnikoff Lizzy Smyth George Pentheroudakis Andres Cervantes ESMO - Eur. Oncology 日本臨床腫瘍学会（JSMO） Thank you. It was a pleasure working with you!

Oncology = communication

So pleased to work with Digestive Cancers Europe and ESMO - Eur. Oncology to develop the ESMO patient guides for #OesophagealCancer & #GastricCancer .

🎙️Check out our latest ESMO Open podcast on controversies in #GIonc : debate between Lizzy Smyth 🇬🇧 and Sarah Derks 🇳🇱 on #MSI in #GastricCancer
ESMO - Eur. Oncology

Oh oh.... 🫢
An all female panel in GI oncology!
What is the world coming to?

Well done TTD 👏🏻👏🏻

Very proud to share the stage with my friends Tania Fleitas Kanonnikoff and Maria Alsina in the beautiful city of Cordoba ☺️

🔴 HIGHLIGHT 🔴 Lizzy Smyth discusses targeted therapies for patients with gastroesophageal cancer
#TTD23

‼️ Quedan pocos días para el XXXI Simposio Internacional: Avances en el Tratamiento de Tumores Digestivos

✅Más de 500 expertos nacionales e internacionales se dan cita para hablar de los últimos avances y técnicas

📅13-15 dic
📍Córdoba
#TTD23

simposiottd.com

1 hour to go!
You do not want to miss it.
Christopher Peters Tom Lizzy Smyth Sheraz Markar Mark Baxter Mary Booth AUGIS Oncology Forum UK The Roux Group OG Surgery Roux Library

🔥 Did I mention cellular therapy is coming to GI cancer?

Great update by Changson Qi on status of CAR-T at #ESMOImmuno23

Great #bispecific session at #ESMOImmuno23

➡️Deep and durable responses to DLL3xCD3 bispecific in SCLC
➡️Dose optimisation reduces significant CRS and ICANS in Phase II #ProjectOptimus

Phase III RCT awaited - a new option in a difficult to treat disease?

Where melanoma goes first, oesophagogastric cancer goes later (I hope..)

☑️Encouraging long-term results for TIL in ICI-pretreated melanoma @ #ESMOImmuno23 ESMO - Eur. Oncology

If any TIL researchers are interested in gastric cancer do get in touch!

#ESMOImmuno23 : Stay abreast of the latest #ScientificFindings in #ImmunoOncology thanks to the #ExpertInsights brought to you by the ESMO Social Media Ambassadors. Keep an eye on these accounts & become part of the conversation.
📌ow.ly/tGsJ50QfyGe

ESMO - Eur. Oncology #ESMOAsia23 grows from strength to strength … enjoyed the discussions esp the women for oncology session led by amazing janice Tsang and Deborah Mukherji .. great work Sanjay Popat 👏👏Lizzy Smyth great session on ctDNA - ! Charles Swanton as always superb work CRUKLondon

An Irish feel to Christmas, in the wake of loss and so much not right globally.

A very well attended early morning session at #ESMOAsia23 ESMO - Eur. Oncology in collaboration with AACR on early cancer detection

Great panel of Lizzy Smyth #YuShyr Charles Swanton Sola Adeleke MBBS, PhD Max Diehn, MD/PhD

Here we go! Join me and Raghav Sundar and Kohei shitara in 402 now for all the latest in #gastric #cancer at #ESMOAsia23

Not your average scientific meeting...

#ESMOAsia23 ESMO - Eur. Oncology

Fantastic opening ceremony with Dragon Dance 🐉!

Looking forward to great science and collaboration with our Asian colleagues!