At long last, we have finally identified a degradation regulator of a specific, pupylated, proteasome substrate! An opus led by student Shoshanna Kahne in collaboration with Aravind group rheelab BhabhaEkiertLab Alejandro Pironti James Chen

My second “first author” paper is published by Nucleic Acids Research! We show how one of the proteins I found from the proteomics screen (Enustun et al., Nat Struct Mol Biol, 2023) is important for mRNA transfer from the phage nucleus and for their translation.

Ever wonder why drug-resistant Mycobacterium tuberculosis is less fit than drug-susceptible Mtb? And how the bacterium can evolve to compensate for that cost?

Our featured article: Inhibitors of bacterial immune systems: discovery, mechanisms and applications go.nature.com/48VGtrL #Review by David Mayo-Muñoz, Rafa Pinilla-Redondo, Sarah Camara-Wilpert, Nils Birkholz & Peter Fineran
Microbiology and Immunology Otago University of Otago Section of Microbiology UCPH Biotech Research & Innovation Centre (BRIC)

After an incredible time in the labs of DaganLab and Sorek Lab, it's time for a new exciting chapter! I am deeply honored the WeinLab will be part of the Systems_Immunology_WIS department at the Weizmann Institute. Can't wait to begin this journey!

A huge congratulations to the recipients of the 2024 @FredHutch Weintraub Graduate Student Award! These twelve exceptional graduate students exemplify the bold, creative, and pioneering spirit embodied by Dr. Hal Weintraub: fredhutch.org/en/news/releas…

Conservation and similarity of bacterial and eukaryotic innate immunity

rdcu.be/dzS7a

Aaron Whiteley and @hannahledvina review the similarities between eukaryotic and bacterial innate immunity, exploring conserved components, signalling and restriction mechanisms.

In this mSphere of Influence commentary, I discuss how 3 papers from Portnoy, Fey and Foster labs have influenced my research and the way I think about how metabolism and resistance are interlinked Foster Lab Aaron Whiteley

Out now nature we report the structural basis of Gabija defense and how the anti-defense phage protein Gad1 wraps around Gabija in an octameric web for immune evasion! 🐙🕸

rdcu.be/drLOR

#b3d #MolecularNodes Brady Johnston

Despite these difficult times, I wanted to share the peer-reviewed version of our latest manuscript, including some new and exciting results!
nature.com/articles/s4158…

come work with us in beautiful Boulder. Job opening in the CU Boulder Center for CryoET. Do you like tomography? and bears in your yard? and marmots in the mountains? check it out! jobs.colorado.edu/jobs/JobDetail…

Host glutathione is required for Rickettsia parkeri to properly septate, avoid ubiquitylation, and survive in macrophages. biorxiv.org/cgi/content/sh… #biorxiv_micrbio

With today’s Nobel Prize news, a shout-out to Bill Studier for cloning T7 RNA polymerase and developing the T7 expression system that allows large production of mRNAs and has had broad impact in many areas of biology. Maybe he should’ve been included. communitynewspapergroup.com/waverly_newspa…

The 2023 WLA Prize in Life Science or Medicine is awarded jointly to Karolin Luger, Daniela Rhodes and Timothy J. Richmond.
CU Boulder 🦬 Cambridge University ETH Zurich
#WLAPrize

JCC Fellows and Alums, would you please send your current contact information to us at: jccfund 'at' yale 'dot' edu ?

We are updating our records and would love to have a database as a resource to help connect current Fellows with Alums.

Thanks in advance and RT's appreciated!

ASM announced the recipients of its 2024 Awards and Prize Program, recognizing leading scientists and researchers in the microbial sciences for their professional accomplishments and contributions to the field: asm.social/1qx #ASMawards